日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Quercetin improves retinal glycolysis to slow myopia progression through orchestrating the AKT/FOXO/HK2 axis

槲皮素通过调控AKT/FOXO/HK2轴改善视网膜糖酵解，从而减缓近视进展。

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2026.104139
Zhang, Ruixue; Zhang, Miao; Xie, Yunxiao; Wei, Huixia; Yang, Zhaohui; Wen, Ying; Hao, Jiawen; Du, Yongle; Yang, Yuanting; Yin, Xuewei; Zhang, Yinqiao; Jiang, Wenjun; Bi, Hongsheng; Guo, Dadong
信号转导
AKT
发表日期：2026
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miR-223-3p improves macrophage polarization balance and mitochondrial metabolism to ameliorate uveitis by orchestrating P65(Lys310) acetylation through RBPJ/HDAC1 axis

miR-223-3p通过RBPJ/HDAC1轴调控P65(Lys310)乙酰化，从而改善巨噬细胞极化平衡和线粒体代谢，进而缓解葡萄膜炎。

期刊:Cellular & Molecular Biology Letters
影响因子:10.2
doi:10.1186/s11658-026-00874-3
Peng, Yuan; Liu, Bin; Xu, Shuqin; Qu, Ruyi; Zhang, Ruixue; Wang, Congling; Liu, Yunfeng; Wei, Huixia; Tian, Qingmei; Zhang, Miao; Bi, Hongsheng; Yin, Xuewei; Guo, Dadong
巨噬细胞
HDAC1
表观遗传
巨噬细胞
信号转导
代谢
线粒体
乙酰化
细胞生物学
免疫/内分泌
发表日期：2026
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Single-cell RNA sequencing reveals anterograde trans-synaptic degeneration and exacerbated synaptic remodeling in myopia.

单细胞 RNA 测序揭示近视中顺行跨突触退化和突触重塑加剧

期刊:Experimental and Molecular Medicine
影响因子:12.9
doi:10.1038/s12276-025-01489-y
Zhang Ruixue, Xie Yunxiao, Zhang Miao, Li Zhiheng, Guo Lijie, Wei Huixia, Li Xiaomeng, Xin Jizhao, Yang Zhaohui, Wen Ying, Hao Jiawen, Li Xianglin, Yin Xuewei, Jiang Wenjun, Bi Hongsheng, Guo Dadong
细胞生物学
单细胞
发表日期：2025
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Therapeutic effect of miR-30b-5p-loaded lentivirus on experimental autoimmune uveitis via inhibiting Notch signaling activation.

miR-30b-5p负载的慢病毒通过抑制Notch信号激活对实验性自身免疫性葡萄膜炎具有治疗作用

期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-025-06438-x
Yin Xuewei, Wei Huixia, Guo Lijie, Liu Bin, Peng Yuan, Zhou Mengxian, Qiu Yan, Qu Ruyi, Gao Yane, Wu Qiuxin, Jiang Wenjun, Bi Hongsheng, Guo Dadong
信号转导
Notch
炎症
发表日期：2025
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Restoration of Immune Homeostasis: The Role of miR-30b-5p and Notch Signaling in Uveitis After Treatment With Longdan Xiegan Decoction

免疫稳态的恢复：miR-30b-5p 和 Notch 信号通路在龙胆泻肝汤治疗葡萄膜炎中的作用

期刊:Mediators of Inflammation
影响因子:4.2
doi:10.1155/mi/8824838
Qiu, Yan; Yin, Xuewei; Guo, Lijie; Wang, Baojian; Zhang, Miao; Xu, Shuqin; Wei, Huixia; Liu, Bin; Gao, Yane; Bi, Hongsheng; Guo, Dadong
信号转导
Notch
免疫/内分泌
发表日期：2025
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Integrated network pharmacology and in vivo experiments to reveal the anti-inflammatory mechanism of Qinghuo Rougan Formula in uveitis

整合网络药理学和体内实验，揭示清火柔肝方治疗葡萄膜炎的抗炎机制

期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2025.1632027
Jing, Changying; Sun, Yaqi; Bi, Hongsheng; Guo, Junguo; Ren, Cong; Song, Jike; Wang, Beibei; Tian, Qingmei; Guo, Dadong; He, Pengjuan; Li, Lijie; Xie, Xiaofeng
发表日期：2025
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Baicalin prevents experimental autoimmune uveitis by promoting macrophage polarization balance through inhibiting the HIF-1α signaling pathway.

黄芩苷通过抑制 HIF-1α 信号通路促进巨噬细胞极化平衡，从而预防实验性自身免疫性葡萄膜炎

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-01286-7
Liu Bin, Peng Yuan, Wang Congling, Wei Huixia, Xu Shuqin, Liu Yunfeng, Yin Xuewei, Bi Hongsheng, Guo Dadong
信号转导
细胞生物学
巨噬细胞
发表日期：2025
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Covariation of scleral remodeling and PI3K/Akt signaling pathway in experimental myopia.

实验性近视中巩膜重塑与PI3K/Akt信号通路的共变

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-97643-7
Li Xiaomeng, Liu Xiaojing, Yu Yingxin, Li Tuling, Guo Lijie, Hu Guili, Wei Huixia, Yang Zhaohui, Liu Jinpeng, Hao Yixian, Zhang Ruixue, Wu Qiuxin, Liao Xuan, Guo Dadong, Bi Hongsheng
信号转导
PI3K/Akt
发表日期：2025
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Research Progress of Epigenetic Modifications in Myopia

近视表观遗传修饰的研究进展

期刊:International Journal of Medical Sciences
影响因子:3.2
doi:10.7150/ijms.110640
Zhang, Yinqiao; Yang, Zhaohui; Zhang, Miao; Yang, Yuanting; Ma, Zhongyu; Wu, Mengke; Bi, Hongsheng; Guo, Dadong
表观遗传
发表日期：2025
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Association between Disorders of Lipid Metabolism and Oculopathy: An Overview

脂质代谢紊乱与眼病之间的关联：概述

期刊:International Journal of Medical Sciences
影响因子:3.2
doi:10.7150/ijms.116512
Yang, Yuanting; Zhang, Ruixue; Zhang, Miao; Yang, Zhaohui; Ma, Zhongyu; Zhang, Yinqiao; Wu, Mengke; Guo, Dadong; Bi, Hongsheng
代谢
发表日期：2025
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