Guo Grace L相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Mutation of PXR phosphorylation motif at Ser347 disrupts lipid and bile acid homeostasis in diet-induced metabolic dysfunction-associated steatohepatitis in mice

小鼠饮食诱导的代谢功能障碍相关性脂肪性肝炎中，PXR磷酸化基序Ser347位点的突变会破坏脂质和胆汁酸稳态。

期刊:Drug Metabolism and Disposition

doi:10.1016/j.dmd.2025.100222

Basaly, Veronia; Henry, Zakiyah R; Taylor, Rulaiha E; Kong, Bo; Yang, Ill; Brinker, Anita; Yang, Zhenning; Zhou, Peihong; Joseph, Laurie B; Aleksunes, Lauren; Buckley, Brian; Negishi, Masahiko; Guo, Grace L

发表日期：2026

文献求助收藏

Deletion of hepatic FXR leads to more severe MASH development in female mice

肝脏FXR基因缺失会导致雌性小鼠发生更严重的MASH（黏膜相关血液系统疾病）

期刊:Hepatology Communications

影响因子:4.6

doi:10.1097/HC9.0000000000000693

Henry, Zakiyah R; Armstrong, Laura; Maliha, Syeda; Jia, Xuelian; Gao, Sophie; Taylor, Rulaiha E; Basaly, Veronia; Otersen, Katherine; Yang, Zhenning; Rizzolo, Daniel; Stofan, Mary; Meadows, Vik; Bhattacharya, Anisha; Zhou, Peihong; Yang, Ill; Brinker, Anita; Zhou, Lanjing; Zhu, Hao; Joseph, Laurie B; Buckley, Brian; Anthony, Tracy; Aleksunes, Lauren; Kong, Bo; Guo, Grace L

发表日期：2025

文献求助收藏

Dual Effects of Maternal Diet and Perinatal Organophosphate Flame Retardant Treatment on Offspring Development, Behavior and Metabolism

母体饮食和围产期有机磷阻燃剂处理对后代发育、行为和代谢的双重影响

影响因子:4.1

doi:10.3390/toxics13080639

Yasrebi, Ali; Rojas, Catherine M; Anthony, Shabree; Feltri, Samantha; Evelyn, Jamilah; Wiersielis, Kimberly; Adams, Samantha; Basaly, Veronia; Guo, Grace L; Aleksunes, Lauren M; Roepke, Troy A

发育与干细胞

发表日期：2025

文献求助收藏

Fibroblast growth factor 15 overexpression and combined peroxisome proliferator-activated receptor α activation attenuates metabolic dysfunction-associated steatohepatitis progression in mice

成纤维细胞生长因子15过表达和过氧化物酶体增殖物激活受体α联合激活可减轻小鼠代谢功能障碍相关性脂肪性肝炎的进展。

期刊:Drug Metabolism and Disposition

doi:10.1016/j.dmd.2025.100128

Shi, Hong; Stofan, Mary; Kong, Bo; Taylor, Rulaiha; Henry, Zakiyah; Maliha, Syeda; Rizzolo, Daniel; Guo, Grace L

成纤维细胞

细胞生物学

发表日期：2025

文献求助收藏

Insights of direct and indirect regulation of PXR through phosphorylation in fatty liver disease

脂肪肝疾病中PXR磷酸化直接和间接调控的见解

期刊:Molecular Pharmacology

doi:10.1016/j.molpha.2024.100014

Basaly, Veronia; Bhattacharya, Anisha; Guo, Grace L

发表日期：2025

文献求助收藏

Ursodeoxycholic acid acts as an ileal FXR agonist in male mice with hepatic deficiency of FXR

熊去氧胆酸在肝脏FXR缺乏的雄性小鼠中作为回肠FXR激动剂发挥作用

doi:10.1136/egastro-2025-100227

Henry, Zakiyah R; Maliha, Syeda; Basaly, Veronia; Yang, Zhenning; Taylor, Rulaiha E; Otersen, Katherine; Meadows, Vik; Rizzolo, Daniel; Stofan, Mary; Bhattacharya, Anisha; Zhou, Peihong; Brinker, Anita; Yang, Ill; Zhang, Lanjing; Joseph, Laurie B; Buckley, Brian; Kong, Bo; Guo, Grace L

发表日期：2025

文献求助收藏

Liver-gut axis signaling regulates circadian energy metabolism in shift workers

肝肠轴信号传导调节轮班工人的昼夜节律能量代谢

期刊:FASEB Journal

影响因子:4.2

doi:10.1096/fj.202402102R

Yang, Zhenning; Zarbl, Helmut; Kong, Bo; Taylor, Rulaiha; Black, Kathleen; Kipen, Howard; Basaly, Veronia; Fang, Mingzhu; Guo, Grace L

发表日期：2024

文献求助收藏

Characterization of individual bile acids in vivo utilizing a novel low bile acid mouse model

利用新型低胆汁酸小鼠模型对体内各种胆汁酸进行表征

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfae029

Taylor, Rulaiha; Yang, Zhenning; Henry, Zakiyah; Capece, Gina; Meadows, Vik; Otersen, Katherine; Basaly, Veronia; Bhattacharya, Anisha; Mera, Stephanie; Zhou, Peihong; Joseph, Laurie; Yang, Ill; Brinker, Anita; Buckley, Brian; Kong, Bo; Guo, Grace L

发表日期：2024

文献求助收藏

Effects of therapeutically approved individual bile acids on the development of metabolic dysfunction-associated steatohepatitis a low bile acid mouse model

治疗性批准的单个胆汁酸对低胆汁酸小鼠模型中代谢功能障碍相关性脂肪性肝炎发展的影响

期刊:Toxicological Sciences

影响因子:4.1

doi:10.1093/toxsci/kfae110

Taylor, Rulaiha; Basaly, Veronia; Kong, Bo; Yang, Ill; Brinker, Anita M; Capece, Gina; Bhattacharya, Anisha; Henry, Zakiyah R; Otersen, Katherine; Yang, Zhenning; Meadows, Vik; Mera, Stephanie; Joseph, Laurie B; Zhou, Peihong; Aleksunes, Lauren M; Roepke, Troy; Buckley, Brian; Guo, Grace L

发表日期：2024

文献求助收藏

Correlations of Long Noncoding RNA HNF4A-AS1 Alternative Transcripts with Liver Diseases and Drug Metabolism.

长链非编码RNA HNF4A-AS1替代转录本与肝脏疾病和药物代谢的相关性

期刊:Drug Metabolism and Disposition

doi:10.1124/dmd.124.001873

Jin Jing, Nguyen Le Tra Giang, Wassef Andrew, Sadek Ragui, Schmitt Timothy M, Guo Grace L, Rasmussen Theodore P, Zhong Xiao-Bo

发表日期：2024

文献求助收藏