Guo HaiYan相关文献与解析，生知库 | 链接生命科学的每一步

Cross-ancestry genome-wide association studies of liver function biomarkers uncover pleiotropic variants, systemic disease links and therapeutic targets

跨种族全基因组关联研究揭示了肝功能生物标志物的多效性变异、系统性疾病关联和治疗靶点。

Yao, Wentao; Fan, Jingyi; Lu, Jing; Guo, Haiyan; Yu, Chengxiao; Wang, Xuehui; Wang, Yun; Zhang, Yu; Duan, Qingning; Cheng, Lihua; Zhou, Chen; Wang, Zhaohui; Dai, Juncheng; Ma, Hongxia; Zhang, Qun; Song, Ci; Shen, Hongbing

发表日期：2026

文献求助收藏

Targeting the lactylation of ENO1 alleviates endothelial dysfunction in sepsis

靶向ENO1乳酸化可缓解脓毒症中的内皮功能障碍

期刊:Clinical and Translational Medicine

影响因子:6.8

doi:10.1002/ctm2.70597

Xie, Xueru; Liu, Tingyan; Zhang, Caiyan; Cheng, Ye; Gao, Yajing; Xiao, Wenfeng; Guo, Haiyan; Zhou, Yutong; Yu, Yawei; Wang, Kexin; Lin, Yinghong; Xiao, Lisheng; Zhang, Yingying; Yang, Weiguo; Yan, Gangfeng; Lu, Guoping; Zhou, Yufeng

Correction: A prospective cohort study on progestin-primed ovarian stimulation vs. GnRH antagonist in IVF-ICSI cycles: effects on clinical pregnancy and neonatal outcomes

更正：一项关于体外受精-卵胞浆内单精子注射（IVF-ICSI）周期中孕激素预处理卵巢刺激与促性腺激素释放激素（GnRH）拮抗剂治疗的前瞻性队列研究：对临床妊娠和新生儿结局的影响

期刊:Journal of Ovarian Research

影响因子:4.2

doi:10.1186/s13048-026-02020-1

Yang, Chuning; Chen, Qiuju; Shen, Xi; Guo, Haiyan; Lin, Jiaying; Lu, Xuefeng; Wen, Xiaowei; Zhu, Qianqian; Chai, Weiran

免疫/内分泌

发表日期：2026

文献求助收藏

Carbon-Coated Probiotics Restore Intestinal Homeostasis to Promote Damage Repair in Inflammatory Bowel Disease

碳包覆益生菌恢复肠道稳态，促进炎症性肠病损伤修复

期刊:Advanced Science

影响因子:14.1

doi:10.1002/advs.202509812

Chen, Xue; Guo, Haiyan; Li, Yuhan; Lin, Qiaowen; Liu, Hua; Hong, Liwen; Wang, Lei; Zhong, Jie; Ni, Dalong; Wang, Zhengting

Correction: Elucidating the role of Nâmyristoylation in the excessive membrane localization of PDâL1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy.

更正：阐明 N'肉豆蔻酰化在缺氧癌症中 PD'L1 过度膜定位中的作用，并开发一种新型 NMT1 抑制剂与免疫检查点阻断疗法联合使用

期刊:Journal of Experimental & Clinical Cancer Research

影响因子:12.8

doi:10.1186/s13046-025-03533-1

Zhao Haoming, Zhang Zhen, Zhang Chaojun, Ma Hexin, Wan Qingqing, Zhao Xinran, Wang Xu, Yan Ming, Guo Haiyan, Zhang Jianjun, Chen Wantao

免疫/内分泌

发表日期：2025

文献求助收藏

DNA binding effects of LDH nanozyme for aseptic osteolysis mitigation through STING pathway modulation

LDH纳米酶通过调节STING通路发挥DNA结合作用，从而减轻无菌性骨溶解。

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-025-03458-z

Fu, Zi; Zhang, Meng; Huang, Ying; Wang, Han; Hao, Wanting; Liu, Zeyang; Guo, Haiyan; Ni, Dalong

Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development

携带Tdrd6变异的精子引起的合子基因表达改变会扰乱早期胚胎发育

期刊:MedComm

影响因子:10.7

doi:10.1002/mco2.70038

Hu, Zhijie; Zhang, Yuqi; Cai, Renfei; Chen, Qiuju; Guo, Haiyan; Li, Danjun; Lin, Weidong; He, Hongxi; Wu, Haibo; Liu, Yali; Li, Bin; Xi, Qianwen; Gao, Hongyuan; Zhang, Jian; Lyu, Qifeng; Kuang, Yanping; Lu, Xuefeng

发育与干细胞

发表日期：2025

文献求助收藏

Temozolomide promotes glioblastoma stemness expression through senescence-associated reprogramming via HIF1Î±/HIF2Î± regulation.

替莫唑胺通过 HIF1α/HIF2α 调控，促进衰老相关重编程，从而促进胶质母细胞瘤干细胞的表达

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-025-07617-w

Wang Pan, Liao Bin, Gong Sheng, Guo HaiYan, Zhao Lu, Liu Jie, Wu Nan

Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates.

巨噬细胞焦亡介导新生儿高氧诱导的炎症性肺损伤

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1546986

Tu Zikun, Guo Haiyan, Gao Yajing, Xiao Wenfeng, Xie Xueru, Yu Hongmiao, Liang Qiuyan, Zhou Yufeng

VAMP4/STX8 Mediate the Autophagic Secretion of Mitochondria and Promote TAMs Polarization in HNSCC.

VAMP4/STX8介导线粒体的自噬分泌并促进HNSCC中TAMs的极化。

Cross-ancestry genome-wide association studies of liver function biomarkers uncover pleiotropic variants, systemic disease links and therapeutic targets

跨种族全基因组关联研究揭示了肝功能生物标志物的多效性变异、系统性疾病关联和治疗靶点。

Targeting the lactylation of ENO1 alleviates endothelial dysfunction in sepsis

靶向ENO1乳酸化可缓解脓毒症中的内皮功能障碍

Correction: A prospective cohort study on progestin-primed ovarian stimulation vs. GnRH antagonist in IVF-ICSI cycles: effects on clinical pregnancy and neonatal outcomes

更正：一项关于体外受精-卵胞浆内单精子注射（IVF-ICSI）周期中孕激素预处理卵巢刺激与促性腺激素释放激素（GnRH）拮抗剂治疗的前瞻性队列研究：对临床妊娠和新生儿结局的影响

Carbon-Coated Probiotics Restore Intestinal Homeostasis to Promote Damage Repair in Inflammatory Bowel Disease

碳包覆益生菌恢复肠道稳态，促进炎症性肠病损伤修复

Correction: Elucidating the role of Nâmyristoylation in the excessive membrane localization of PDâL1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy.

更正：阐明 N'肉豆蔻酰化在缺氧癌症中 PD'L1 过度膜定位中的作用，并开发一种新型 NMT1 抑制剂与免疫检查点阻断疗法联合使用

DNA binding effects of LDH nanozyme for aseptic osteolysis mitigation through STING pathway modulation

LDH纳米酶通过调节STING通路发挥DNA结合作用，从而减轻无菌性骨溶解。

Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development

携带Tdrd6变异的精子引起的合子基因表达改变会扰乱早期胚胎发育

Temozolomide promotes glioblastoma stemness expression through senescence-associated reprogramming via HIF1Î±/HIF2Î± regulation.

替莫唑胺通过 HIF1α/HIF2α 调控，促进衰老相关重编程，从而促进胶质母细胞瘤干细胞的表达

Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates.

巨噬细胞焦亡介导新生儿高氧诱导的炎症性肺损伤

VAMP4/STX8 Mediate the Autophagic Secretion of Mitochondria and Promote TAMs Polarization in HNSCC.

VAMP4/STX8介导线粒体的自噬分泌并促进HNSCC中TAMs的极化。

Cross-ancestry genome-wide association studies of liver function biomarkers uncover pleiotropic variants, systemic disease links and therapeutic targets

跨种族全基因组关联研究揭示了肝功能生物标志物的多效性变异、系统性疾病关联和治疗靶点。

Targeting the lactylation of ENO1 alleviates endothelial dysfunction in sepsis

靶向ENO1乳酸化可缓解脓毒症中的内皮功能障碍

Correction: A prospective cohort study on progestin-primed ovarian stimulation vs. GnRH antagonist in IVF-ICSI cycles: effects on clinical pregnancy and neonatal outcomes

更正：一项关于体外受精-卵胞浆内单精子注射（IVF-ICSI）周期中孕激素预处理卵巢刺激与促性腺激素释放激素（GnRH）拮抗剂治疗的前瞻性队列研究：对临床妊娠和新生儿结局的影响

Carbon-Coated Probiotics Restore Intestinal Homeostasis to Promote Damage Repair in Inflammatory Bowel Disease

碳包覆益生菌恢复肠道稳态，促进炎症性肠病损伤修复

Correction: Elucidating the role of Nâmyristoylation in the excessive membrane localization of PDâL1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy.

更正：阐明 N'肉豆蔻酰化在缺氧癌症中 PD'L1 过度膜定位中的作用，并开发一种新型 NMT1 抑制剂与免疫检查点阻断疗法联合使用

DNA binding effects of LDH nanozyme for aseptic osteolysis mitigation through STING pathway modulation

LDH纳米酶通过调节STING通路发挥DNA结合作用，从而减轻无菌性骨溶解。

Altered zygotic gene expression caused by sperm with Tdrd6 variants disrupts early embryonic development

携带Tdrd6变异的精子引起的合子基因表达改变会扰乱早期胚胎发育

Temozolomide promotes glioblastoma stemness expression through senescence-associated reprogramming via HIF1Î±/HIF2Î± regulation.

替莫唑胺通过 HIF1α/HIF2α 调控，促进衰老相关重编程，从而促进胶质母细胞瘤干细胞的表达

Macrophage pyroptosis mediates hyperoxia-induced inflammatory lung injury in neonates.

巨噬细胞焦亡介导新生儿高氧诱导的炎症性肺损伤

Correction: Elucidating the role of Nâmyristoylation in the excessive membrane localization of PDâL1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy.