日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Correction: Immune microenvironment-dependent effects of age-associated Bifidobacterium strains on gut immunity and microbial diversity

更正：年龄相关双歧杆菌菌株对肠道免疫和微环境多样性的免疫微环境依赖性影响

期刊:Frontiers in Cellular and Infection Microbiology
影响因子:4.8
doi:10.3389/fcimb.2026.1809832
He, Yaqin; Zhang, Furui; Tian, Zhiqiang; Li, Ruyi; Su, Ming; Hong, Liping; Wen, Jun; Zhang, Cao; Tian, Jinhai; Guo, Le
免疫/内分泌
发表日期：2026
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Identification of the disulfidptosis-related gene G6PD as a potential biomarker and therapeutic target in pancreatic ductal adenocarcinoma by integrative bioinformatics analysis and experimental validation

通过整合生物信息学分析和实验验证，鉴定出二硫键凋亡相关基因G6PD是胰腺导管腺癌的潜在生物标志物和治疗靶点。

期刊:Discover Oncology
影响因子:2.9
doi:10.1007/s12672-026-04753-3
Su, Shuangyan; Wu, Bihua; Han, Tingting; Wang, XianYu; Lou, Fenglin; Mei, Zhenghao; Guo, Le
凋亡
肿瘤
表观遗传
G6PD
肿瘤免疫
发表日期：2026
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Hippocampus- and neocortex-specific deletion of Aeg-1 causes learning memory impairment and depression in mice.

小鼠海马和新皮层特异性敲除 Aeg-1 会导致学习记忆障碍和抑郁症

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07508-0
Wang Ya-He, Zhou Ning, Wan Pan-Pan, Li Xin-Tong, Yu Chun-Yang, Chou Jinjiang, Feng Zong-Yi, Zhang Lian-Xiang, Li Juan-Juan, Yu Bao-Cong, Tang Zhen-Ning, Liu Kun-Mei, Guo Le
神经科学
抑郁症
Hippo
发表日期：2025
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The role of GPI-anchored membrane-bound alkaline phosphatase in the mode of action of Bt Cry1A toxins in the diamondback moth

GPI锚定膜结合碱性磷酸酶在小菜蛾Bt Cry1A毒素作用方式中的作用

期刊:Fundamental Research
影响因子:6.3
doi:10.1016/j.fmre.2024.05.007
Sun, Dan; Xu, Qiuchen; Guo, Le; Bai, Yang; Shentu, Xuping; Yu, Xiaoping; Crickmore, Neil; Zhou, Xuguo; Bravo, Alejandra; Soberón, Mario; Zhang, Youjun; Guo, Zhaojiang
发表日期：2025
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Diagnosis of Sarcopenia Using Convolutional Neural Network Models Based on Muscle Ultrasound Images: Prospective Multicenter Study

基于肌肉超声图像的卷积神经网络模型在肌少症诊断中的应用：前瞻性多中心研究

期刊:Journal of Medical Internet Research
影响因子:6
doi:10.2196/70545
Chen, Zi-Tong; Li, Xiao-Long; Jin, Feng-Shan; Shi, Yi-Lei; Zhang, Lei; Yin, Hao-Hao; Zhu, Yu-Li; Tang, Xin-Yi; Lin, Xi-Yuan; Lu, Bei-Lei; Wang, Qun; Sun, Li-Ping; Zhu, Xiao-Xiang; Qiu, Li; Xu, Hui-Xiong; Guo, Le-Hang
发表日期：2025
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Gram-positive enhancer matrix delivering FVpE via M cell targeting elicit protective mucosal and adaptive immune responses against Helicobacter pylori infection

革兰氏阳性增强子基质通过靶向M细胞递送FVpE，可诱导针对幽门螺杆菌感染的保护性黏膜和适应性免疫反应。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1697591
Zhang, Furui; He, Yaqin; Liu, Hongpeng; Wu, Jing; Li, Xin; Chen, Jiale; Ni, Linhan; Zhang, Zhen; Chen, Juan; Liu, Kunmei; Guo, Le
炎症/感染
细胞生物学
免疫/内分泌
发表日期：2025
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Bone marrow mesenchymal stem cell-derived exosomes alleviate DSS-induced inflammatory bowel disease in mice through inhibiting intestinal epithelial cell pyroptosis via delivery of TSG-6

骨髓间充质干细胞来源的外泌体通过递送TSG-6抑制肠上皮细胞焦亡，从而缓解DSS诱导的小鼠炎症性肠病。

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1601591
Wu, Bihua; Su, Shuangyan; Wang, Xianyu; Li, Yuwei; Mei, Zhenghao; Lou, Fenglin; Guo, Le
外泌体
发育与干细胞
炎症
表观遗传
焦亡
炎症/感染
上皮细胞
干细胞
细胞生物学
发表日期：2025
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Dysregulated programmed cell death of intestinal epithelial cells in ulcerative colitis: Molecular mechanisms and novel therapeutic interventions (Review)

溃疡性结肠炎中肠上皮细胞程序性细胞死亡失调：分子机制和新型治疗干预（综述）

期刊:International Journal of Molecular Medicine
影响因子:5.8
doi:10.3892/ijmm.2025.5671
Wu, Bihua; Su, Shuangyan; Li, Yuwei; Guo, Le
上皮细胞
细胞生物学
结肠炎
肠炎
发表日期：2025
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Enhancing Cartilage Repair in Osteoarthritis Using Platelet Lysates and Arthroscopic Microfracture.

利用血小板裂解物和关节镜微骨折术增强骨关节炎软骨修复

期刊:Drug Design Development and Therapy
影响因子:5.1
doi:10.2147/DDDT.S502935
Zhang Haiyan, Li Dipeng, Zheng Wei, Hua Jiaqing, Chen Zuxiang, Xu Wenting, Zhu Jianing, Wang Yue, Chen Xiaotian, Chen Huixin, Guo Le, Yuan Qiang, Zhou Li, Shan Letian
免疫/内分泌
关节炎
发表日期：2025
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Immune microenvironment-dependent effects of age-associated Bifidobacterium strains on gut immunity and microbial diversity

年龄相关双歧杆菌菌株对肠道免疫和微生物多样性的免疫微环境依赖性影响

期刊:Frontiers in Cellular and Infection Microbiology
影响因子:4.8
doi:10.3389/fcimb.2025.1639178
He, Yaqin; Zhang, Furui; Tian, Zhiqiang; Li, Ruyi; Su, Ming; Hong, Liping; Wen, Jun; Zhang, Cao; Tian, Jinhai; Guo, Le
微生物学
免疫/内分泌
发表日期：2025
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