Guo Yelei相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

DUSP6 ablation restores CAR T-cell fitness impaired by tumor CD58 loss through invigoration of AP-1 signaling

DUSP6 消融可通过增强 AP-1 信号传导来恢复因肿瘤 CD58 丢失而受损的 CAR T 细胞活性。

期刊:Signal Transduction and Targeted Therapy

影响因子:52.7

doi:10.1038/s41392-026-02597-5

Ma, Xinran; Zhang, Yang; Wang, Yao; Han, Fuxin; Lu, Yuting; Tong, Chuan; Guo, Yelei; Wei, Jianshu; Zhu, Qi; Dong, Liang; Cao, Zhi; Meng, Zhenzhen; Shi, Jinhong; Wu, Zhiqiang; Han, Weidong

细胞生物学

发表日期：2026

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Reciprocal activation of antigen-presenting cells and CAR T cells triggers a widespread endogenous anti-tumor immune response through sustained high-level IFNγ production

抗原呈递细胞和CAR-T细胞的相互激活通过持续高水平的IFNγ产生，触发广泛的内源性抗肿瘤免疫反应。

期刊:Cancer Biology & Medicine

影响因子:8.4

doi:10.20892/j.issn.2095-3941.2023.0324

Guo, Yelei; Tong, Chuan; Wu, Zhiqiang; Lu, Yuting; Wang, Yao; Han, Weidong

细胞生物学

免疫/内分泌

发表日期：2023

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CD58 loss in tumor cells confers functional impairment of CAR T cells

肿瘤细胞中CD58的缺失会导致CAR T细胞功能受损。

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2022007891

Yan, Xin; Chen, Deyun; Ma, Xinran; Wang, Yao; Guo, Yelei; Wei, Jianshu; Tong, Chuan; Zhu, Qi; Lu, Yuting; Yu, Yang; Wu, Zhiqiang; Han, Weidong

细胞生物学

免疫/内分泌

发表日期：2022

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Clinical development of CAR T cell therapy in China: 2020 update

中国CAR-T细胞疗法临床开发：2020年最新进展

期刊:Cellular & Molecular Immunology

影响因子:19.8

doi:10.1038/s41423-020-00555-x

Wei, Jianshu; Guo, Yelei; Wang, Yao; Wu, Zhiqiang; Bo, Jian; Zhang, Bin; Zhu, Jun; Han, Weidong

细胞生物学

免疫/内分泌

发表日期：2021

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Mutant B2M-HLA-E and B2M-HLA-G fusion proteins protects universal chimeric antigen receptor-modified T cells from allogeneic NK cell-mediated lysis

突变型B2M-HLA-E和B2M-HLA-G融合蛋白可保护通用嵌合抗原受体修饰的T细胞免受同种异体NK细胞介导的溶解作用。

期刊:European Journal of Immunology

影响因子:3.7

doi:10.1002/eji.202049107

Guo, Yelei; Xu, Beilei; Wu, Zhiqiang; Bo, Jian; Tong, Chuan; Chen, Deyun; Wang, Jin; Wang, Haoyi; Wang, Yao; Han, Weidong

细胞生物学

免疫/内分泌

发表日期：2021

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Correction to: Bispecific CAR-T cells targeting both CD19 and CD22 for therapy of adults with relapsed or refractory B cell acute lymphoblastic leukemia

更正：靶向CD19和CD22的双特异性CAR-T细胞用于治疗复发或难治性B细胞急性淋巴细胞白血病成人患者

期刊:Journal of Hematology & Oncology

影响因子:40.4

doi:10.1186/s13045-020-00878-2

Dai, Hanren; Wu, Zhiqiang; Jia, Hejin; Tong, Chuan; Guo, Yelei; Ti, Dongdong; Han, Xiao; Liu, Yang; Zhang, Wenying; Wang, Chunmeng; Zhang, Yajing; Chen, Meixia; Yang, Qingming; Wang, Yao; Han, Weidong

细胞生物学

免疫/内分泌

发表日期：2020

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Optimized tandem CD19/CD20 CAR-engineered T cells in refractory/relapsed B-cell lymphoma

优化串联 CD19/CD20 CAR 工程化 T 细胞治疗难治性/复发性 B 细胞淋巴瘤

影响因子:23.1

doi:10.1182/blood.2020005278

Tong, Chuan; Zhang, Yajing; Liu, Yang; Ji, Xingyu; Zhang, Wenying; Guo, Yelei; Han, Xiao; Ti, Dongdong; Dai, Hanren; Wang, Chunmeng; Yang, Qingming; Liu, Wanli; Wang, Yao; Wu, Zhiqiang; Han, Weidong

细胞生物学

发表日期：2020

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Efficiency and side effects of anti-CD38 CAR T cells in an adult patient with relapsed B-ALL after failure of bi-specific CD19/CD22 CAR T cell treatment

在接受双特异性 CD19/CD22 CAR T 细胞治疗失败后复发的成人 B 细胞急性淋巴细胞白血病患者中，抗 CD38 CAR T 细胞的疗效和副作用

期刊:Cellular & Molecular Immunology

影响因子:19.8

doi:10.1038/s41423-019-0355-5

Guo, Yelei; Feng, Kaichao; Tong, Chuan; Jia, Hejin; Liu, Yang; Wang, Yao; Ti, Dongdong; Yang, Qingming; Wu, Zhiqiang; Han, Weidong

细胞生物学

发表日期：2020

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Efficacy and biomarker analysis of CD133-directed CAR T cells in advanced hepatocellular carcinoma: a single-arm, open-label, phase II trial.

CD133靶向CAR T细胞治疗晚期肝细胞癌的疗效和生物标志物分析：一项单臂、开放标签的II期试验

期刊:Oncoimmunology

影响因子:6.3

doi:10.1080/2162402X.2020.1846926

Dai Hanren, Tong Chuan, Shi Daiwei, Chen Meixia, Guo Yelei, Chen Deyun, Han Xiao, Wang Hua, Wang Yao, Shen Pingping

细胞生物学

发表日期：2020

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Haploidentical CD19/CD22 bispecific CAR-T cells induced MRD-negative remission in a patient with relapsed and refractory adult B-ALL after haploidentical hematopoietic stem cell transplantation

单倍体相合CD19/CD22双特异性CAR-T细胞在单倍体相合造血干细胞移植后，使复发难治性成人B细胞急性淋巴细胞白血病患者达到微小残留病灶阴性缓解。

期刊:Journal of Hematology & Oncology

影响因子:40.4

doi:10.1186/s13045-019-0741-6

Jia, Hejin; Wang, Zhenguang; Wang, Yao; Liu, Yang; Dai, Hanren; Tong, Chuan; Guo, Yelei; Guo, Bo; Ti, Dongdong; Han, Xiao; Yang, Qingming; Wu, Zhiqiang; Han, Weidong

发育与干细胞

细胞生物学

免疫/内分泌

发表日期：2019

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