The AKT inhibitor AZD5363 elicits synthetic lethality in ARID1A-deficient gastric cancer cells via induction of pyroptosis.
AKT 抑制剂 AZD5363 通过诱导细胞焦亡，在 ARID1A 缺陷型胃癌细胞中引起合成致死
期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-024-02778-5
Fang Menghan, Lin Youfen, Xue Chaorong, Sheng Kaiqin, Guo Zegeng, Han Yuting, Lin Hanbin, Wu Yuecheng, Sang Yuchao, Chen Xintan, Howell Stephen B, Lin Xu, Lin Xinjian
