日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Polθ activity modulates sensitivity to standard therapies in DNMT3A-deficient leukemia.

Polθ 活性调节 DNMT3A 缺陷型白血病对标准疗法的敏感性。

Le Bac Viet, Vekariya Umeshkumar, Toma Monika M, Nieborowska-Skorska Margaret, Caron Marie-Christine, Gozdecka Malgorzata, Haydar Zayd, Walsh Martin, Ghosh Jayashri, Vaughan-Williams Elaine, Podszywalow-Bartnicka Paulina, Kukuyan Anna-Mariya, Ziolkowska Sylwia, Atkins Jessica, Hadzijusufovic Emir, Chandramouly Gurushankar, Nejati Reza, Piwocka Katarzyna, Pomerantz Richard, Vassiliou George S, Huntly Brian J P, Valent Peter, Wasik Mariusz, Bellacosa Alfonso, Masson Jean-Yves, Gupta Gaorav P, Challen Grant A, Skorski Tomasz

Investigating initial patterns of progression on first-line treatment in patients with de novo metastatic breast cancer

研究初诊转移性乳腺癌患者一线治疗后的初始进展模式

Huber, Emily; Gupta, Gaorav P; Morse, Ryan; Abdou, Yara; Aldrich, Jeffrey; Carey, Lisa A; Dees, E Claire; Ray, Emily M; Reeder-Hayes, Katherine E; Jones, Ellen; Wright, Jean L; Sud, Shivani; Casey, Dana L

Bridging the gap: ctDNA, genomics, and equity in breast cancer care

弥合差距:ctDNA、基因组学与乳腺癌治疗中的公平性

Aronson, Julia; Bhatta, Manasa; Carey, Lisa A; Jobanputra, Kunal; Gupta, Gaorav P; Abdou, Yara

Tumor suppressors in Sox2-mediated lung cancers promote distinct cell-intrinsic and immunologic remodeling.

Sox2 介导的肺癌中的肿瘤抑制因子促进独特的细胞内在和免疫重塑

Sengottuvel Nisitha, Whately Kristina M, Modliszewski Jennifer L, Sellers Rani S, Green William D, Gong Weida, Woods Allison T, Livingston Eric W, Fagan-Solis Katerina D, Cannon Gabrielle, Edatt Lincy, Yuan Hong, Chack Aaron C, Sanchez Yazmin, Zhou Katherine, Dawoud Alyaa, Green Jarred M, Godfrey Virginia, Milner J Justin, Gupta Gaorav P, Pecot Chad V

Polymerase θ-what does it see, and why does it matter for cancer therapy?

聚合酶θ——它看到了什么?为什么它对癌症治疗很重要?

Ramsden, Dale A; Gupta, Gaorav P

Unveiling cGAS mechanisms: Insights into DNA damage and immune sensing in cancer

揭示cGAS机制:深入了解癌症中的DNA损伤和免疫感知

Cho, Min-Guk; Gupta, Gaorav P

Corrigendum to "Unveiling cGAS mechanisms: Insights into DNA damage and immune sensing in cancer" [DNA Repair 152 (2025) 103868]

对“揭示 cGAS 机制:深入了解癌症中的 DNA 损伤和免疫感知”的更正 [DNA Repair 152 (2025) 103868]

Cho, Min-Guk; Gupta, Gaorav P

Hierarchical Coordination of Polymerase Theta and RAD51 Resolves Clustered Replication Fork Collapse

聚合酶Theta和RAD51的层级协调作用解决了簇状复制叉崩溃问题

Smith, Chelsea M; Simpson, Dennis A; Guerra, Paolo; Feng, Wanjuan; Ellington, Simon W; Lu, Dongbo; Fijen, Carel; Boylston, Natalie M; Chiruvella, Kishore K; El-Shiekh, Iman; Lee, Rachel; Wozny, Anne-Sophie; Pregnall, Andrew M; Eckenroth, Brian E; El-Sagheer, Afaf H; Brown, Tom; Doublié, Sylvie; Ramsden, Dale A; Rothenberg, Eli; Nik-Zainal, Serena; Gupta, Gaorav P

Quality of Life Outcomes in Breast Cancer Patients Receiving Chemotherapy With or Without Radiation Therapy

接受化疗(无论是否联合放疗)的乳腺癌患者的生活质量结局

Morse, Ryan T; Bean, Nathan W; Hall, Jacob; Deal, Allison; Nyrop, Kirsten A; Abdou, Yara; Dees, Elizabeth C; Ray, Emily M; Jolly, Trevor A; Reeder-Hayes, Katherine E; Jones, Ellen; Gupta, Gaorav P; Elmore, Shekinah; Muss, Hyman B; Casey, Dana L

PEARL: A Phase Ib/II Biomarker Study of Adding Radiation Therapy to Pembrolizumab Before Neoadjuvant Chemotherapy in Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer

PEARL:一项Ib/II期生物标志物研究,旨在评估在人表皮生长因子受体2阴性乳腺癌患者新辅助化疗前,将放射疗法加入帕博利珠单抗治疗方案的疗效。

Ho, Alice Y; Shiao, Stephen; Kobald, Samantha A; Chen, Jonathan; Duda, Dan G; Ly, Amy; Bossuyt, Veerle; Cho, Hae Lin; Arnold, Brittany; Knott, Simon; Gupta, Gaorav P; McAndrew, Philomena; Karlan, Scott; Tighiouart, Mourad; Muzikansky, Alona; Basho, Reva; McArthur, Heather