日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis

结核分枝杆菌中磷酸核糖转移酶介导的细胞壁前体合成的结构分析

期刊:Nature Microbiology
影响因子:19.4
doi:10.1038/s41564-024-01643-8
Gao, Shan; Wu, Fangyu; Gurcha, Sudagar S; Batt, Sarah M; Besra, Gurdyal S; Rao, Zihe; Zhang, Lu
细胞生物学
发表日期：2024
文献求助 收藏

Author Correction: The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth

作者更正：分枝杆菌糖苷水解酶 LamH 可促进荚膜阿拉伯甘露聚糖的释放并刺激生长。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-51724-9
Franklin, Aaron; Salgueiro, Vivian C; Layton, Abigail J; Sullivan, Rudi; Mize, Todd; Vázquez-Iniesta, Lucía; Benedict, Samuel T; Gurcha, Sudagar S; Anso, Itxaso; Besra, Gurdyal S; Banzhaf, Manuel; Lovering, Andrew L; Williams, Spencer J; Guerin, Marcelo E; Scott, Nichollas E; Prados-Rosales, Rafael; Lowe, Elisabeth C; Moynihan, Patrick J
发表日期：2024
文献求助 收藏

Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis

结核分枝杆菌AG生物合成所需的启动阿拉伯糖基转移酶AftA的结构

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2302858120
Gong, Yicheng; Wei, Chuancun; Wang, Jun; Mu, Nengjiang; Lu, Qinhong; Wu, Chengyao; Yan, Ning; Yang, Huifang; Zhao, Yao; Yang, Xiuna; Gurcha, Sudagar S; Veerapen, Natacha; Batt, Sarah M; Hao, Zhiqiang; Da, Lintai; Besra, Gurdyal S; Rao, Zihe; Zhang, Lu
发表日期：2023
文献求助 收藏

NSC19723, a Thiacetazone-Like Benzaldehyde Thiosemicarbazone Improves the Efficacy of TB Drugs In Vitro and In Vivo

NSC19723 是一种硫乙酰酮类苯甲醛缩氨基硫脲，可提高结核病药物在体内和体外的疗效

期刊:Microbiology Spectrum
影响因子:3.7
doi:10.1128/spectrum.02592-22
Padam Singh, Srishti Rawat, Ashish Kumar Agrahari, Manisha Singh, Saurabh Chugh, Sudagar Gurcha, Albel Singh, Katherine Abrahams, Gurdyal S Besra, Shailendra Asthana, Diwan S Rawat, Ramandeep Singh
发表日期：2022
文献求助 收藏

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB(2)-AcpM(2)

分枝杆菌阿拉伯糖基转移酶复合物 EmbB(2)-AcpM(2) 的冷冻电镜快照

期刊:Protein & Cell
影响因子:12.8
doi:10.1007/s13238-020-00726-6
Zhang, Lu; Zhao, Yao; Gao, Ruogu; Li, Jun; Yang, Xiuna; Gao, Yan; Zhao, Wei; Gurcha, Sudagar S; Veerapen, Natacha; Batt, Sarah M; Besra, Kajelle Kaur; Xu, Wenqing; Bi, Lijun; Zhang, Xian'en; Guddat, Luke W; Yang, Haitao; Wang, Quan; Besra, Gurdyal S; Rao, Zihe
发表日期：2020
文献求助 收藏

Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes

荧光甘露糖苷是眼虫细胞膜中糖基转移酶和糖-1-磷酸转移酶活性的受体底物。

期刊:Carbohydrate Research
影响因子:2.5
doi:10.1016/j.carres.2016.11.017
Ivanova, Irina M; Nepogodiev, Sergey A; Saalbach, Gerhard; O'Neill, Ellis C; Urbaniak, Michael D; Ferguson, Michael A J; Gurcha, Sudagar S; Besra, Gurdyal S; Field, Robert A
信号转导
细胞生物学
IF
发表日期：2017
文献求助 收藏

Identification of KasA as the cellular target of an anti-tubercular scaffold

确定 KasA 为抗结核支架的细胞靶点

期刊:Nature Communications
影响因子:14.7
doi:10.1038/ncomms12581
Katherine A Abrahams, Chun-Wa Chung, Sonja Ghidelli-Disse, Joaquín Rullas, María José Rebollo-López, Sudagar S Gurcha, Jonathan A G Cox, Alfonso Mendoza, Elena Jiménez-Navarro, María Santos Martínez-Martínez, Margarete Neu, Anthony Shillings, Paul Homes, Argyrides Argyrou, Ruth Casanueva, Nicholas J
免疫
细胞生物学
其它细胞
发表日期：2016
文献求助 收藏

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target

分枝杆菌天冬氨酰tRNA合成酶AspS的生化和结构表征，AspS是一种有前景的结核病药物靶点

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0113568
Gurcha, Sudagar S; Usha, Veeraraghavan; Cox, Jonathan A G; Fütterer, Klaus; Abrahams, Katherine A; Bhatt, Apoorva; Alderwick, Luke J; Reynolds, Robert C; Loman, Nicholas J; Nataraj, VijayaShankar; Alemparte, Carlos; Barros, David; Lloyd, Adrian J; Ballell, Lluis; Hobrath, Judith V; Besra, Gurdyal S
发表日期：2014
文献求助 收藏

Keto-mycolic acid-dependent pellicle formation confers tolerance to drug-sensitive Mycobacterium tuberculosis

酮-霉菌酸依赖性菌膜形成赋予结核分枝杆菌对药物敏感菌的耐受性

期刊:mBio
影响因子:4.7
doi:10.1128/mBio.00222-13
Sambandan, Dhinakaran; Dao, Dee N; Weinrick, Brian C; Vilchèze, Catherine; Gurcha, Sudagar S; Ojha, Anil; Kremer, Laurent; Besra, Gurdyal S; Hatfull, Graham F; Jacobs, William R Jr
发表日期：2013
文献求助 收藏

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.

脐带因子和肽聚糖通过 mincle/CARD9 信号传导和炎症小体重现了分枝杆菌的 Th17 促进佐剂活性

期刊:Journal of Immunology
影响因子:3.4
doi:10.4049/jimmunol.1203343
Shenderov Kevin, Barber Daniel L, Mayer-Barber Katrin D, Gurcha Sudagar S, Jankovic Dragana, Feng Carl G, Oland Sandy, Hieny Sara, Caspar Pat, Yamasaki Sho, Lin Xin, Ting Jenny P-Y, Trinchieri Giorgio, Besra Gurdyal S, Cerundolo Vincenzo, Sher Alan
信号转导
炎性小体
炎症
发表日期：2013
文献求助 收藏