日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural analysis of phosphoribosyltransferase-mediated cell wall precursor synthesis in Mycobacterium tuberculosis

结核分枝杆菌中磷酸核糖转移酶介导的细胞壁前体合成的结构分析

期刊:Nature Microbiology
影响因子:19.4
doi:10.1038/s41564-024-01643-8
Gao, Shan; Wu, Fangyu; Gurcha, Sudagar S; Batt, Sarah M; Besra, Gurdyal S; Rao, Zihe; Zhang, Lu
细胞生物学
发表日期：2024
文献求助 收藏

Author Correction: The mycobacterial glycoside hydrolase LamH enables capsular arabinomannan release and stimulates growth

作者更正：分枝杆菌糖苷水解酶 LamH 可促进荚膜阿拉伯甘露聚糖的释放并刺激生长。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-51724-9
Franklin, Aaron; Salgueiro, Vivian C; Layton, Abigail J; Sullivan, Rudi; Mize, Todd; Vázquez-Iniesta, Lucía; Benedict, Samuel T; Gurcha, Sudagar S; Anso, Itxaso; Besra, Gurdyal S; Banzhaf, Manuel; Lovering, Andrew L; Williams, Spencer J; Guerin, Marcelo E; Scott, Nichollas E; Prados-Rosales, Rafael; Lowe, Elisabeth C; Moynihan, Patrick J
发表日期：2024
文献求助 收藏

DprE2 is a molecular target of the anti-tubercular nitroimidazole compounds pretomanid and delamanid

DprE2 是抗结核硝基咪唑类化合物普瑞托马尼和德拉马尼的分子靶点。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-39300-z
Abrahams, Katherine A; Batt, Sarah M; Gurcha, Sudagar S; Veerapen, Natacha; Bashiri, Ghader; Besra, Gurdyal S
发表日期：2023
文献求助 收藏

Structure of the priming arabinosyltransferase AftA required for AG biosynthesis of Mycobacterium tuberculosis

结核分枝杆菌AG生物合成所需的启动阿拉伯糖基转移酶AftA的结构

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2302858120
Gong, Yicheng; Wei, Chuancun; Wang, Jun; Mu, Nengjiang; Lu, Qinhong; Wu, Chengyao; Yan, Ning; Yang, Huifang; Zhao, Yao; Yang, Xiuna; Gurcha, Sudagar S; Veerapen, Natacha; Batt, Sarah M; Hao, Zhiqiang; Da, Lintai; Besra, Gurdyal S; Rao, Zihe; Zhang, Lu
发表日期：2023
文献求助 收藏

Cryo-EM snapshots of mycobacterial arabinosyltransferase complex EmbB(2)-AcpM(2)

分枝杆菌阿拉伯糖基转移酶复合物 EmbB(2)-AcpM(2) 的冷冻电镜快照

期刊:Protein & Cell
影响因子:12.8
doi:10.1007/s13238-020-00726-6
Zhang, Lu; Zhao, Yao; Gao, Ruogu; Li, Jun; Yang, Xiuna; Gao, Yan; Zhao, Wei; Gurcha, Sudagar S; Veerapen, Natacha; Batt, Sarah M; Besra, Kajelle Kaur; Xu, Wenqing; Bi, Lijun; Zhang, Xian'en; Guddat, Luke W; Yang, Haitao; Wang, Quan; Besra, Gurdyal S; Rao, Zihe
发表日期：2020
文献求助 收藏

The singular Corynebacterium glutamicum Emb arabinofuranosyltransferase polymerises the α(1 → 5) arabinan backbone in the early stages of cell wall arabinan biosynthesis

谷氨酸棒状杆菌特有的Emb阿拉伯呋喃糖基转移酶在细胞壁阿拉伯聚糖生物合成的早期阶段聚合α(1→5)阿拉伯聚糖骨架。

期刊:Cell Surface
影响因子:6.2
doi:10.1016/j.tcsw.2018.06.003
Jankute, Monika; Alderwick, Luke J; Moorey, Alice R; Joe, Maju; Gurcha, Sudagar S; Eggeling, Lothar; Lowary, Todd L; Dell, Anne; Pang, Poh-Choo; Yang, Tiandi; Haslam, Stuart; Besra, Gurdyal S
细胞生物学
发表日期：2018
文献求助 收藏

Fluorescent mannosides serve as acceptor substrates for glycosyltransferase and sugar-1-phosphate transferase activities in Euglena gracilis membranes

荧光甘露糖苷是眼虫细胞膜中糖基转移酶和糖-1-磷酸转移酶活性的受体底物。

期刊:Carbohydrate Research
影响因子:2.5
doi:10.1016/j.carres.2016.11.017
Ivanova, Irina M; Nepogodiev, Sergey A; Saalbach, Gerhard; O'Neill, Ellis C; Urbaniak, Michael D; Ferguson, Michael A J; Gurcha, Sudagar S; Besra, Gurdyal S; Field, Robert A
信号转导
细胞生物学
IF
发表日期：2017
文献求助 收藏

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target

分枝杆菌天冬氨酰tRNA合成酶AspS的生化和结构表征，AspS是一种有前景的结核病药物靶点

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0113568
Gurcha, Sudagar S; Usha, Veeraraghavan; Cox, Jonathan A G; Fütterer, Klaus; Abrahams, Katherine A; Bhatt, Apoorva; Alderwick, Luke J; Reynolds, Robert C; Loman, Nicholas J; Nataraj, VijayaShankar; Alemparte, Carlos; Barros, David; Lloyd, Adrian J; Ballell, Lluis; Hobrath, Judith V; Besra, Gurdyal S
发表日期：2014
文献求助 收藏

Keto-mycolic acid-dependent pellicle formation confers tolerance to drug-sensitive Mycobacterium tuberculosis

酮-霉菌酸依赖性菌膜形成赋予结核分枝杆菌对药物敏感菌的耐受性

期刊:mBio
影响因子:4.7
doi:10.1128/mBio.00222-13
Sambandan, Dhinakaran; Dao, Dee N; Weinrick, Brian C; Vilchèze, Catherine; Gurcha, Sudagar S; Ojha, Anil; Kremer, Laurent; Besra, Gurdyal S; Hatfull, Graham F; Jacobs, William R Jr
发表日期：2013
文献求助 收藏

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.

脐带因子和肽聚糖通过 mincle/CARD9 信号传导和炎症小体重现了分枝杆菌的 Th17 促进佐剂活性

期刊:Journal of Immunology
影响因子:3.4
doi:10.4049/jimmunol.1203343
Shenderov Kevin, Barber Daniel L, Mayer-Barber Katrin D, Gurcha Sudagar S, Jankovic Dragana, Feng Carl G, Oland Sandy, Hieny Sara, Caspar Pat, Yamasaki Sho, Lin Xin, Ting Jenny P-Y, Trinchieri Giorgio, Besra Gurdyal S, Cerundolo Vincenzo, Sher Alan
信号转导
炎性小体
炎症
发表日期：2013
文献求助 收藏