Gurney Mark E相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

ROC Analysis of Biomarker Combinations in Fragile X Syndrome-Specific Clinical Trials: Evaluating Treatment Efficacy via Exploratory Biomarkers

脆性X综合征特异性临床试验中生物标志物组合的ROC分析：通过探索性生物标志物评估治疗效果

期刊:Translational Psychiatry

影响因子:6.2

doi:10.1038/s41398-025-03558-2

Norris, Jordan E; Berry-Kravis, Elizabeth M; Harnett, Mark D; Reines, Scott A; Smith, Melody R; Auger, Emma K; Outterson, Abigail H; Furman, Jeremiah; Gurney, Mark E; Ethridge, Lauren E

发表日期：2025

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Auditory N1 event-related potential amplitude is predictive of serum concentration of BPN14770 in fragile X syndrome

听觉N1事件相关电位振幅可预测脆性X综合征患者血清中BPN14770的浓度。

期刊:Molecular Autism

影响因子:5.5

doi:10.1186/s13229-024-00626-0

Norris, Jordan E; Berry-Kravis, Elizabeth M; Harnett, Mark D; Reines, Scott A; Reese, Melody A; Outterson, Abigail H; Michalak, Claire; Furman, Jeremiah; Gurney, Mark E; Ethridge, Lauren E

发表日期：2024

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Auditory N1 event-related potential amplitude is predictive of serum concentration of BPN14770 in fragile x syndrome

听觉N1事件相关电位振幅可预测脆性X综合征患者血清中BPN14770的浓度。

doi:10.21203/rs.3.rs-4474353/v1

Norris, Jordan E; Berry-Kravis, Elizabeth M; Harnett, Mark D; Reines, Scott A; Reese, Melody A; Outterson, Abigail H; Michalak, Claire; Furman, Jeremiah; Gurney, Mark E; Ethridge, Lauren E

发表日期：2024

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COVID-19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the US

新冠肺炎与痴呆症：基于美国电子健康记录的风险、差异和结果分析

期刊:Alzheimers & Dementia

影响因子:11.1

doi:10.1002/alz.12296

Wang, QuanQiu; Davis, Pamela B; Gurney, Mark E; Xu, Rong

发表日期：2021

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Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization

阿尔茨海默病中肠道菌群-小胶质细胞-大脑相互作用：基于知识的多维度表征

期刊:Alzheimers Research & Therapy

影响因子:7.6

doi:10.1186/s13195-021-00917-1

Wang, QuanQiu; Davis, Pamela B; Qi, Xin; Chen, Shu G; Gurney, Mark E; Perry, George; Doraiswamy, P Murali; Xu, Rong

阿尔茨海默症

细胞生物学

发表日期：2021

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Discovery, Radiolabeling, and Evaluation of Subtype-Selective Inhibitors for Positron Emission Tomography Imaging of Brain Phosphodiesterase-4D

脑磷酸二酯酶-4D正电子发射断层扫描成像亚型选择性抑制剂的发现、放射性标记和评价

期刊:ACS Chemical Neuroscience

影响因子:3.9

doi:10.1021/acschemneuro.0c00077

Wakabayashi, Yuichi; Telu, Sanjay; Dick, Rachel M; Fujita, Masahiro; Ooms, Maarten; Morse, Cheryl L; Liow, Jeih-San; Hong, Jinsoo S; Gladding, Robert L; Manly, Lester S; Zoghbi, Sami S; Mo, Xuesheng; D'Amato, Emily C; Sindac, Janice A; Nugent, Richard A; Marron, Brian E; Gurney, Mark E; Innis, Robert B; Pike, Victor W

发表日期：2020

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Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders

选择性磷酸二酯酶4D (PDE4D) 变构抑制剂的设计与合成及其在脆性X综合征和其他脑部疾病治疗中的应用

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.9b00193

Gurney, Mark E; Nugent, Richard A; Mo, Xuesheng; Sindac, Janice A; Hagen, Timothy J; Fox, David 3rd; O'Donnell, James M; Zhang, Chong; Xu, Ying; Zhang, Han-Ting; Groppi, Vincent E; Bailie, Marc; White, Ronald E; Romero, Donna L; Vellekoop, A Samuel; Walker, Joel R; Surman, Matthew D; Zhu, Lei; Campbell, Robert F

发表日期：2019

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Protection from Amyloid β Peptide-Induced Memory, Biochemical, and Morphological Deficits by a Phosphodiesterase-4D Allosteric Inhibitor

磷酸二酯酶-4D变构抑制剂对淀粉样β肽诱导的记忆、生化和形态缺陷的保护作用

期刊:Journal of Pharmacology and Experimental Therapeutics

影响因子:3.8

doi:10.1124/jpet.119.259986

Cui, Su-Ying; Yang, Ming-Xin; Zhang, Yong-He; Zheng, Victor; Zhang, Han-Ting; Gurney, Mark E; Xu, Ying; O'Donnell, James M

发表日期：2019

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Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice

BPN14770（一种磷酸二酯酶-4D变构抑制剂）对野生型和人源化小鼠的记忆增强作用

期刊:Neuropsychopharmacology

影响因子:7.1

doi:10.1038/s41386-018-0178-6

Zhang, Chong; Xu, Ying; Chowdhary, Anirudh; Fox, David 3rd; Gurney, Mark E; Zhang, Han-Ting; Auerbach, Benjamin D; Salvi, Richard J; Yang, Mingxin; Li, Gaowen; O'Donnell, James M

发表日期：2018

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Phosphodiesterase-4 (PDE4) molecular pharmacology and Alzheimer's disease

磷酸二酯酶-4 (PDE4) 分子药理学与阿尔茨海默病

期刊:Neurotherapeutics

影响因子:6.9

doi:10.1007/s13311-014-0309-7

Gurney, Mark E; D'Amato, Emily C; Burgin, Alex B

阿尔茨海默症

发表日期：2015

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