日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A Randomized, Placebo-Controlled Trial of Hydroxychloroquine in Incomplete Lupus

羟氯喹治疗不完全性红斑狼疮的随机、安慰剂对照试验

Olsen, Nancy J; Liao, Duanping; James, Judith A; Guthridge, Joel M; Arriens, Cristina; Kamen, Diane; Ishimori, Mariko; Wallace, Daniel J; Striebich, Christopher; Narain, Sonali; Chong, Benjamin F; He, Fan; Schaefer, Eric W; Chinchilli, Vernon M; Karp, David R

A population-scale atlas of blood and tissue in lupus nephritis

狼疮性肾炎血液和组织人群图谱

Sugiarto, Nicholas W; Gurajala, Siddarth; Curtis, Michelle; Eisenhaure, Thomas M; Arazi, Arnon; Fava, Andrea; Xiao, Qian; Mears, Joseph; Rovin, Brad; Berthier, Celine C; Zhao, Yu; Izmirly, Peter M; Barnas, Jennifer L; Hoover, Paul J; Peters, Michael; Raychowdhury, Raktima; Horisberger, Alice; Sakaue, Saori; Furie, Richard A; Belmont, H Michael; Hildeman, David A; Woodle, E Steve; Dall'Era, Maria; Putterman, Chaim; Kamen, Diane L; McMahon, Maureen A; Grossman, Jennifer; Kalunian, Kenneth C; Hodgin, Jeffrey B; Payan-Schober, Fernanda; Apruzzese, William; Perlman, Harris; Cuda, Carla M; Wofsy, David; Guthridge, Joel M; Anolik, Jennifer H; James, Judith A; Rao, Deepak A; Davidson, Anne; Petri, Michelle A; Buyon, Jill P; Hacohen, Nir; Diamond, Betty; Raychaudhuri, Soumya

A highly prevalent lupus risk haplotype increases IRF7-dependent induction of IFN-α, enhancing antiviral defense and exacerbating autoimmunity

一种高发的狼疮风险单倍型会增加IRF7依赖的IFN-α诱导,从而增强抗病毒防御并加剧自身免疫。

Virolainen, Samuel J; Creighton, Kathryn; Dashtiahangar, Maryam; Krishnamurthy, Durga; Parks, Lois; Forney, Carmy; Ampadu, Britney; Rudrapatna, Akshata N; Dunn, Katelyn A; Parameswaran, Sreeja; Hesse, Hayley K; Chen, Xiaoting; VonHandorf, Andrew; Edsall, Lee E; Yin, Cailing; Lynch, Arthur; Gittens, Olivia E; Diouf, Arame A; Jones, Sydney H; Hass, Matthew; Javier, Ellen; Donmez, Omer A; Keddari, Yasine; Danzinger, Oded; Seelamneni, Harsha; Namjou-Khales, Bahram; Ainsworth, Hannah C; Comeau, Mary E; Marion, Miranda C; Glenn, Stuart B; Nath, Swapan K; Freedman, Barry I; Tsao, Betty P; Kamen, Diane L; Brown, Elizabeth E; Gilkeson, Gary S; Alarcón, Graciela S; Reveille, John D; James, Judith A; Criswell, Lindsey A; Vilá, Luis M; Alarcón-Riquelme, Marta E; Petri, Michelle; Scofield, R Hal; Kimberly, Robert P; Ramsey-Goldman, Rosalind; Bae, Sang-Cheol; Graham, Deborah Cunninghame; Vyse, Timothy J; Guthridge, Joel M; Gaffney, Patrick M; Langefeld, Carl D; Kelly, Jennifer A; Kaufman, Kenneth M; Sivils, Kathy; Harley, John B; Shen, Nan; Lawson, Lucinda P; Baglaenko, Yuriy; Miraldi, Emily R; Rosenberg, Brad R; Siggers, Trevor; Waggoner, Stephen N; Weirauch, Matthew T; Kottyan, Leah C

Human hypofunctional NCF1 variants promote pulmonary fibrosis in the bleomycin-induced mouse model and patients with systemic sclerosis via expansion of SPP1(+) monocytes-derived macrophages

人类低功能性 NCF1 变体通过 SPP1(+) 单核细胞衍生的巨噬细胞的扩增,促进博来霉素诱导的小鼠模型和系统性硬化症患者的肺纤维化。

Yuan, Xinran; Qin, Xiaodong; Takemoto, Kenji; Zhao, Jian; Sanderson, Matthew; Xu, Xue; Zhang, Yu; Helke, Kristi L; Jacobs Wolf, Bethany; Guthridge, Joel M; James, Judith A; Zhou, Xiaodong; Assassi, Shervin; Feghali-Bostwick, Carol; Wang, Dandan; Sun, Lingyun; Tsao, Betty P

Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis

血液免疫表型分析可识别狼疮性肾炎患者不同的肾脏组织病理学特征和预后。

Horisberger, Alice; Griffith, Alec; Keegan, Joshua; Arazi, Arnon; Pulford, John; Murzin, Ekaterina; Howard, Kaitlyn; Hancock, Brandon; Fava, Andrea; Sasaki, Takanori; Ghosh, Tusharkanti; Inamo, Jun; Beuschel, Rebecca; Cao, Ye; Preisinger, Katie; Gutierrez-Arcelus, Maria; Eisenhaure, Thomas M; Guthridge, Joel; Hoover, Paul J; Dall'Era, Maria; Wofsy, David; Kamen, Diane L; Kalunian, Kenneth C; Furie, Richard; Belmont, Michael; Izmirly, Peter; Clancy, Robert; Hildeman, David; Woodle, E Steve; Apruzzese, William; McMahon, Maureen A; Grossman, Jennifer; Barnas, Jennifer L; Payan-Schober, Fernanda; Ishimori, Mariko; Weisman, Michael; Kretzler, Matthias; Berthier, Celine C; Hodgin, Jeffrey B; Demeke, Dawit S; Putterman, Chaim; Brenner, Michael B; Anolik, Jennifer H; Raychaudhuri, Soumya; Hacohen, Nir; James, Judith A; Davidson, Anne; Petri, Michelle A; Buyon, Jill P; Diamond, Betty; Zhang, Fan; Lederer, James A; Rao, Deepak A

A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated macrophages in lupus nephritis

人鼠肾内髓系细胞图谱揭示了狼疮性肾炎中保守的疾病相关巨噬细胞

Hoover, Paul J; Raparia, Chirag; Lieb, David J; Tzur, Yochay; Kang, Joyce; Arazi, Arnon; Leavitt, Rollin; Mishra, Rakesh; Shah, Sujal I; Simmons, Daimon; Li, Stephen; Peters, Michael; Eisenhaure, Thomas; Few-Cooper, Timothy J; Gurajala, Saisram S; Sonny, Abraham; Hodgin, Jeffrey B; Berthier, Celine C; Guthridge, Joel M; Fava, Andrea; Clancy, Robert M; Putterman, Chaim; Izmirly, Peter M; Belmont, H Michael; Kalunian, Kenneth; Kamen, Diane; Wofsy, David; Buyon, Jill P; James, Judith A; Petri, Michelle; Diamond, Betty; Raychaudhuri, Soumya; Shen-Orr, Shai S; Hacohen, Nir; Davidson, Anne

Identification of Sjögren's disease-associated T cell receptor motifs through deep sequencing

通过深度测序鉴定干燥综合征相关T细胞受体基序

Jupudi, Ananth Aditya; Joachims, Michelle L; Lawrence, Christina; Lopez-Davis, Charmaine; Khatri, Bhuwan; Rasmussen, Astrid; Grundahl, Kiely; Scofield, R Hal; James, Judith A; Guthridge, Joel M; Lessard, Christopher J; Thompson, Linda F; Farris, A Darise

Prospective SARS-CoV-2 additional vaccination in immunosuppressant-treated individuals with autoimmune diseases in a randomized controlled trial

在一项随机对照试验中,对接受免疫抑制剂治疗的自身免疫性疾病患者进行SARS-CoV-2额外疫苗接种的预期效果

Mackay, Meggan; Wagner, Catriona A; Pinckney, Ashley; Cohen, Jeffrey A; Wallace, Zachary S; Khosroshahi, Arezou; Sparks, Jeffrey A; Lord, Sandra; Saxena, Amit; Caricchio, Roberto; Kim, Alfred Hj; Kamen, Diane L; Koumpouras, Fotios; Askanase, Anca D; Smith, Kenneth; Guthridge, Joel M; Pardo, Gabriel; Mao-Draayer, Yang; Macwana, Susan; McCarthy, Sean; Sherman, Matthew A; Daneshfar Hamrah, Sanaz; Veri, Maria; Walker, Sarah; York, Kate; Tedeschi, Sara K; Wang, Jennifer; Dziubla, Gabrielle E; Castro, Mike; Carroll, Robin; Narpala, Sandeep R; Lin, Bob C; Serebryannyy, Leonid; McDermott, Adrian B; Barry, William T; Goldmuntz, Ellen; McNamara, James; Payne, Aimee S; Bar-Or, Amit; Khanna, Dinesh; James, Judith A

Digitally Quantifying Growth and Verdancy of Lolium Plants In Vitro

利用数字化方法量化黑麦草植物体外生长和绿度

Depetris, Mara B; Dimech, Adam M; Guthridge, Kathryn M

Dysregulated soluble immune mediators and lupus-associated autoantibody specificities inform the development of immune indexes that characterise classified SLE transition and SLE disease activity

失调的可溶性免疫介质和狼疮相关自身抗体的特异性为构建免疫指标提供了信息,这些免疫指标可以表征系统性红斑狼疮(SLE)的疾病进展和活动性。

Munroe, Melissa E; Young, Kendra; Lu, Rufei; Guthridge, Joel M; Kamen, Diane L; Gilkeson, Gary S; Weisman, Michael H; Ishimori, Mariko L; Wallace, Daniel J; Karp, David R; Tsokos, George C; Keith, Michael P; Harley, John B; Norris, Jill M; James, Judith A