日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant.

Profilin 基因的剪接缺陷改变了裂殖酵母 SMN 突变体中的肌动蛋白动力学

Antoine Marie, Patrick Kristin L, Soret Johann, Duc Pauline, Rage Florence, Cacciottolo Rebecca, Nissen Kelly E, Cauchi Ruben J, Krogan Nevan J, Guthrie Christine, Gachet Yannick, Bordonné Rémy

Prp8 positioning of U5 snRNA is linked to 5' splice site recognition

U5 snRNA的Prp8定位与5'剪接位点识别相关

MacRae, Andrew J; Mayerle, Megan; Hrabeta-Robinson, Eva; Chalkley, Robert J; Guthrie, Christine; Burlingame, Alma L; Jurica, Melissa S

Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency

Prp8 的 RNaseH 结构域中的结构开关有助于平衡剪接保真度和催化效率。

Mayerle, Megan; Raghavan, Madhura; Ledoux, Sarah; Price, Argenta; Stepankiw, Nicholas; Hadjivassiliou, Haralambos; Moehle, Erica A; Mendoza, Senén D; Pleiss, Jeffrey A; Guthrie, Christine; Abelson, John

The histone variant H2A.Z promotes splicing of weak introns

组蛋白变体H2A.Z促进弱内含子的剪接

Nissen, Kelly E; Homer, Christina M; Ryan, Colm J; Shales, Michael; Krogan, Nevan J; Patrick, Kristin L; Guthrie, Christine

Genetics and biochemistry remain essential in the structural era of the spliceosome

在剪接体的结构时代,遗传学和生物化学仍然至关重要。

Mayerle, Megan; Guthrie, Christine

The crystal structure of S. cerevisiae Sad1, a catalytically inactive deubiquitinase that is broadly required for pre-mRNA splicing

酿酒酵母Sad1的晶体结构,Sad1是一种催化失活的去泛素化酶,广泛参与前体mRNA剪接。

Hadjivassiliou, Haralambos; Rosenberg, Oren S; Guthrie, Christine

Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: exploring the applications of high-resolution genetic interaction mapping of point mutations

基因互作分析点突变能够以残基水平的分辨率探究基因功能:探索高分辨率基因互作图谱在点突变中的应用

Braberg, Hannes; Moehle, Erica A; Shales, Michael; Guthrie, Christine; Krogan, Nevan J

From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II

从结构到系统:RNA聚合酶II的高分辨率定量遗传分析

Braberg, Hannes; Jin, Huiyan; Moehle, Erica A; Chan, Yujia A; Wang, Shuyi; Shales, Michael; Benschop, Joris J; Morris, John H; Qiu, Chenxi; Hu, Fuqu; Tang, Leung K; Fraser, James S; Holstege, Frank C P; Hieter, Philip; Guthrie, Christine; Kaplan, Craig D; Krogan, Nevan J

Diverse forms of RPS9 splicing are part of an evolving autoregulatory circuit

RPS9剪接的多种形式是不断演化的自身调节回路的一部分。

Plocik, Alex M; Guthrie, Christine

Regulation of the Dbp5 ATPase cycle in mRNP remodeling at the nuclear pore: a lively new paradigm for DEAD-box proteins

核孔处mRNP重塑过程中Dbp5 ATPase循环的调控:DEAD-box蛋白的一个充满活力的新范式

Ledoux, Sarah; Guthrie, Christine