Senescence-induced p21(high) macrophages contributed to CD8(+) T cells-related immune hyporesponsiveness in kidney transplantation via Zfp36/IL-27 axis
衰老诱导的p21(high)巨噬细胞通过Zfp36/IL-27轴导致肾移植中CD8(+) T细胞相关的免疫低反应性。
期刊:Cell Discovery
影响因子:12.5
doi:10.1038/s41421-025-00784-2
Zhu, Tingting; Shen, Qixia; Shen, Lingling; Wang, Yucheng; Zhu, Bochen; Ma, Lifeng; Feng, Shi; Wang, Cuili; Yan, Sijing; Li, Jingyi; Chen, Zhimin; Zhou, Jingyi; Huang, Hongfeng; Li, Bingjue; Shen, Zhouji; Wang, Qian; Wang, Jianwei; Gwinner, Wilfried; Scheffner, Irina; Rong, Song; Yang, Bing; Wang, Junwen; Haller, Hermann; Han, Xiaoping; Guo, Guoji; Yin, Zhinan; Jin, Jin; Lan, Hui-Yao; Chen, Jianghua; Jiang, Hong
巨噬细胞
T细胞
巨噬细胞
Senescence
IL-27
CD8
T细胞
衰老
IL-2
细胞生物学
免疫/内分泌
