Gynther相关文献与解析，生知库 | 链接生命科学的每一步

Sex-specific changes in protein expression of membrane transporters in the brain cortex of 5xFAD mouse model of Alzheimer's disease

5xFAD 阿尔茨海默病小鼠模型大脑皮层膜转运蛋白表达的性别特异性变化

期刊:Frontiers in Pharmacology

影响因子:4.4

doi:10.3389/fphar.2024.1365051

Elena Puris, Liudmila Saveleva, Seppo Auriola, Mikko Gynther, Katja M Kanninen, Gert Fricker

The Role of Solute Carrier Transporters in Efficient Anticancer Drug Delivery and Therapy

溶质载体转运蛋白在高效抗癌药物递送和治疗中的作用

期刊:Pharmaceutics

影响因子:5.5

doi:10.3390/pharmaceutics15020364

Puris, Elena; Fricker, Gert; Gynther, Mikko

Monoacylglycerol Lipase Inhibitor JJKK048 Ameliorates ABCG2 Transporter-Mediated Regorafenib Resistance Induced by Hypoxia in Triple Negative Breast Cancer Cells

单酰甘油脂肪酶抑制剂 JJKK048 改善三阴性乳腺癌细胞中缺氧诱导的 ABCG2 转运蛋白介导的瑞戈非尼耐药性

期刊:Journal of Pharmaceutical Sciences

影响因子:3.7

doi:10.1016/j.xphs.2023.05.012

Elena Puris, Sabrina Petralla, Seppo Auriola, Heidi Kidron, Gert Fricker, Mikko Gynther

Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer's Disease

家族性阿尔茨海默病小鼠模型中，慢性脂多糖给药导致大脑皮质 cPLA2 表达和活性增加

期刊:Pharmaceutics

影响因子:4.9

doi:10.3390/pharmaceutics14112438

Mikko Gynther, Mariana Leal Estrada, Sanna Loppi, Paula Korhonen, Katja M Kanninen, Tarja Malm, Jari Koistinaho, Seppo Auriola, Gert Fricker, Elena Puris

Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?

靶向转运蛋白向大脑输送药物：我们能否做得更好？

期刊:Pharmaceutical Research

影响因子:4.3

doi:10.1007/s11095-022-03241-x

Puris, Elena; Fricker, Gert; Gynther, Mikko

神经科学

发表日期：2022

文献求助收藏

Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice

转基因 APdE9 小鼠中脂多糖诱发的全身炎症引发的代谢组学和脂质组学变化

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-021-92602-4

Elena Puris #, Štěpán Kouřil #, Lukáš Najdekr, Sanna Loppi, Paula Korhonen, Katja M Kanninen, Tarja Malm, Jari Koistinaho, David Friedecký, Mikko Gynther

代谢

发表日期：2021

文献求助收藏

The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality

OATP1B1 跨膜结构域中单核苷酸变异对体外功能的影响

期刊:Pharmaceutical Research

影响因子:3.5

doi:10.1007/s11095-021-03107-8

Wilma Kiander, Kati-Sisko Vellonen, Melina M Malinen, Mikko Gynther, Marja Hagström, Madhushree Bhattacharya, Seppo Auriola, Jan B Koenderink, Heidi Kidron

信号转导

发表日期：2021

文献求助收藏

L-Type Amino Acid Transporter 1-Utilizing Prodrugs of Ketoprofen Can Efficiently Reduce Brain Prostaglandin Levels

型氨基酸转运体 1-利用酮洛芬的前体药物可有效降低脑前列腺素水平

期刊:Pharmaceutics

影响因子:4.9

doi:10.3390/pharmaceutics12040344

Ahmed Montaser, Marko Lehtonen, Mikko Gynther, Kristiina M Huttunen

信号转导

发表日期：2020

文献求助收藏

L-Type amino acid transporter 1 as a target for drug delivery

L型氨基酸转运蛋白1作为药物递送靶点

期刊:Pharmaceutical Research

影响因子:4.3

doi:10.1007/s11095-020-02826-8

Puris, Elena; Gynther, Mikko; Auriola, Seppo; Huttunen, Kristiina M

发表日期：2020

文献求助收藏

Editorial: New approaches to overcome the blood-brain barrier for the treatment of CNS disorders

社论：克服血脑屏障治疗中枢神经系统疾病的新方法

Sex-specific changes in protein expression of membrane transporters in the brain cortex of 5xFAD mouse model of Alzheimer's disease

5xFAD 阿尔茨海默病小鼠模型大脑皮层膜转运蛋白表达的性别特异性变化

The Role of Solute Carrier Transporters in Efficient Anticancer Drug Delivery and Therapy

溶质载体转运蛋白在高效抗癌药物递送和治疗中的作用

Monoacylglycerol Lipase Inhibitor JJKK048 Ameliorates ABCG2 Transporter-Mediated Regorafenib Resistance Induced by Hypoxia in Triple Negative Breast Cancer Cells

单酰甘油脂肪酶抑制剂 JJKK048 改善三阴性乳腺癌细胞中缺氧诱导的 ABCG2 转运蛋白介导的瑞戈非尼耐药性

Increased Expression and Activity of Brain Cortical cPLA2 Due to Chronic Lipopolysaccharide Administration in Mouse Model of Familial Alzheimer's Disease

家族性阿尔茨海默病小鼠模型中，慢性脂多糖给药导致大脑皮质 cPLA2 表达和活性增加

Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?

靶向转运蛋白向大脑输送药物：我们能否做得更好？

Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice

转基因 APdE9 小鼠中脂多糖诱发的全身炎症引发的代谢组学和脂质组学变化

The Effect of Single Nucleotide Variations in the Transmembrane Domain of OATP1B1 on in vitro Functionality

OATP1B1 跨膜结构域中单核苷酸变异对体外功能的影响

L-Type Amino Acid Transporter 1-Utilizing Prodrugs of Ketoprofen Can Efficiently Reduce Brain Prostaglandin Levels

型氨基酸转运体 1-利用酮洛芬的前体药物可有效降低脑前列腺素水平

L-Type amino acid transporter 1 as a target for drug delivery

L型氨基酸转运蛋白1作为药物递送靶点