日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy

发现一种新型 NAMPT 抑制剂,可选择性靶向 NAPRT 缺陷型 EMT 亚型癌细胞并缓解化疗引起的周围神经病变

Minjee Kim, Hyeyoung Kim, Bu-Gyeong Kang, Jooyoung Lee, Taegun Kim, Hwanho Lee, Jane Jung, Myung Joon Oh, Seungyoon Seo, Myung-Jeom Ryu, Yeojin Sung, Yunji Lee, Jeonghun Yeom, Gyoonhee Han, Sun-Shin Cha, Hosung Jung, Hyun Seok Kim

CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD2

CXXC5 通过 PGD2 介导 DHT 诱导的雄激素性脱发

Yeong Chan Ryu, Jiyeon Park, You-Rin Kim, Sehee Choi, Geon-Uk Kim, Eunhwan Kim, Yumi Hwang, Heejene Kim, Gyoonhee Han, Soung-Hoon Lee, Kang-Yell Choi

Combination of the LARS1 Inhibitor, BC-LI-0186 with a MEK1/2 Inhibitor Enhances the Anti-Tumor Effect in Non-Small Cell Lung Cancer

LARS1 抑制剂 BC-LI-0186 与 MEK1/2 抑制剂联合使用可增强非小细胞肺癌的抗肿瘤作用

Sang Hoon Lee, Eun Young Kim, Jung Min Han, Gyoonhee Han, Yoon Soo Chang

A newly developed PLD1 inhibitor ameliorates rheumatoid arthritis by regulating pathogenic T and B cells and inhibiting osteoclast differentiation

新开发的 PLD1 抑制剂通过调节致病性 T 细胞和 B 细胞以及抑制破骨细胞分化来改善类风湿性关节炎

Jin-Sil Park, SeungCheon Yang, Doona Song, Sung-Min Kim, JeongWon Choi, Hye Yeon Kang, Ha Yeon Jeong, Gyoonhee Han, Do Sik Min, Mi-La Cho, Sung-Hwan Park

Inhibition of phospholipase D1 induces immunogenic cell death and potentiates cancer immunotherapy in colorectal cancer

抑制磷脂酶 D1 可诱导免疫原性细胞死亡并增强结直肠癌的癌症免疫治疗

Won Chan Hwang #, Doona Song #, Hyesung Lee #, Changmok Oh, Seong Hun Lim, Hyeon Jeong Bae, Nam Doo Kim, Gyoonhee Han, Do Sik Min

Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/Reperfusion Injury in Rat Hearts by Modulating NRF2

Brite 脂肪细胞 FGF21 通过调节 NRF2 减轻大鼠心脏缺血/再灌注损伤

Hanbyeol Moon, Jung-Won Choi, Byeong-Wook Song, Il-Kwon Kim, Soyeon Lim, Seahyoung Lee, Gyoonhee Han, Ki-Chul Hwang, Sang Woo Kim

Pyruvate Kinase M2 Promotes Hair Regeneration by Connecting Metabolic and Wnt/β-Catenin Signaling

丙酮酸激酶 M2 通过连接代谢和 Wnt/β-Catenin 信号促进毛发再生

Yeong Chan Ryu, You-Rin Kim, Jiyeon Park, Sehee Choi, Won-Ji Ryu, Geon-Uk Kim, Eunhwan Kim, Yumi Hwang, Heejene Kim, Gyoonhee Han, Soung-Hoon Lee, Kang-Yell Choi

Novel positive allosteric modulator of protease-activated receptor 1 promotes skin wound healing in hairless mice

蛋白酶激活受体 1 的新型正变构调节剂促进无毛小鼠的皮肤伤口愈合

Yohan Seo, Yunkyung Heo, Sungwoo Jo, So-Hyeon Park, Chulho Lee, Jiwon Chang, Dong-Kyu Jeon, Tae Gun Kim, Gyoonhee Han, Wan Namkung

Suppressing Pyroptosis Augments Post-Transplant Survival of Stem Cells and Cardiac Function Following Ischemic Injury

抑制细胞焦亡可增强干细胞移植后的存活率和缺血性损伤后的心脏功能

Chang Youn Lee, Seahyoung Lee, Seongtae Jeong, Jiyun Lee, Hyang-Hee Seo, Sunhye Shin, Jun-Hee Park, Byeong-Wook Song, Il-Kwon Kim, Jung-Won Choi, Sang Woo Kim, Gyoonhee Han, Soyeon Lim, Ki-Chul Hwang

PRMT5 promotes DNA repair through methylation of 53BP1 and is regulated by Src-mediated phosphorylation

PRMT5 通过 53BP1 甲基化促进 DNA 修复,并受 Src 介导的磷酸化调控

Jee Won Hwang, Su-Nam Kim, Nayeon Myung, Doona Song, Gyoonhee Han, Gyu-Un Bae, Mark T Bedford, Yong Kee Kim