日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Depletion of Akt1 and Akt2 Impairs the Repair of Radiation-Induced DNA Double Strand Breaks via Homologous Recombination

Akt1 和 Akt2 的耗竭会损害通过同源重组修复辐射诱导的 DNA 双链断裂

Tahereh Mohammadian Gol, H Peter Rodemann, Klaus Dittmann

Nanog Signaling Mediates Radioresistance in ALDH-Positive Breast Cancer Cells

Nanog 信号介导 ALDH 阳性乳腺癌细胞的放射抗性

Mozhgan Dehghan Harati, H Peter Rodemann, Mahmoud Toulany

Stress-Induced Phosphorylation of Nuclear YB-1 Depends on Nuclear Trafficking of p90 Ribosomal S6 Kinase

应激诱导的核 YB-1 磷酸化依赖于 p90 核糖体 S6 激酶的核运输

Aadhya Tiwari, Simone Rebholz, Eva Maier, Mozhgan Dehghan Harati, Daniel Zips, Christine Sers, H Peter Rodemann, Mahmoud Toulany

Akt1 and Akt3 but not Akt2 through interaction with DNA-PKcs stimulate proliferation and post-irradiation cell survival of K-RAS-mutated cancer cells

Akt1 和 Akt3(而非 Akt2)通过与 DNA-PKcs 相互作用刺激 K-RAS 突变癌细胞的增殖和照射后细胞存活

Mahmoud Toulany, Julia Maier, Mari Iida, Simone Rebholz, Marina Holler, Astrid Grottke, Manfred Jüker, Deric L Wheeler, Ulrich Rothbauer, H Peter Rodemann

New roles for nuclear EGFR in regulating the stability and translation of mRNAs associated with VEGF signaling

核 EGFR 在调节与 VEGF 信号传导相关的 mRNA 的稳定性和翻译中的新作用

Klaus Dittmann, Claus Mayer, Stefan Czemmel, Stephan M Huber, H Peter Rodemann

Akt1 Stimulates Homologous Recombination Repair of DNA Double-Strand Breaks in a Rad51-Dependent Manner

Akt1 以 Rad51 依赖的方式刺激 DNA 双链断裂的同源重组修复

Katharina Mueck, Simone Rebholz, Mozhgan Dehghan Harati, H Peter Rodemann, Mahmoud Toulany

Dual Targeting of Akt and mTORC1 Impairs Repair of DNA Double-Strand Breaks and Increases Radiation Sensitivity of Human Tumor Cells

Akt 和 mTORC1 的双重靶向作用会损害 DNA 双链断裂的修复并增加人类肿瘤细胞的放射敏感性

Marina Holler, Astrid Grottke, Katharina Mueck, Julia Manes, Manfred Jücker, H Peter Rodemann, Mahmoud Toulany

Dual targeting of PI3K and MEK enhances the radiation response of K-RAS mutated non-small cell lung cancer

PI3K 和 MEK 的双重靶向作用可增强 K-RAS 突变非小细胞肺癌的放射反应

Mahmoud Toulany, Mari Iida, Simone Keinath, Firdevs F Iyi, Katharina Mueck, Birgit Fehrenbacher, Wael Y Mansour, Martin Schaller, Deric L Wheeler, H Peter Rodemann

Nuclear EGFR renders cells radio-resistant by binding mRNA species and triggering a metabolic switch to increase lactate production

核EGFR通过结合mRNA物种并触发代谢转换来增加乳酸的产生,从而使细胞具有放射抗性

Klaus Dittmann, Claus Mayer, Angela Paasch, Stephan Huber, Birgit Fehrenbacher, Martin Schaller, H Peter Rodemann

ERK2-dependent reactivation of Akt mediates the limited response of tumor cells with constitutive K-RAS activity to PI3K inhibition

ERK2 依赖的 Akt 再激活介导具有组成性 K-RAS 活性的肿瘤细胞对 PI3K 抑制的有限反应

Mahmoud Toulany, Minjmaa Minjgee, Mohammad Saki, Marina Holler, Friedegund Meier, Wolfgang Eicheler, H Peter Rodemann