MDM2 antagonist nutlin-3 is a potent inducer of apoptosis in pediatric acute lymphoblastic leukemia cells with wild-type p53 and overexpression of MDM2

MDM2 拮抗剂 nutlin-3 是具有野生型 p53 和 MDM2 过度表达的儿童急性淋巴细胞白血病细胞中细胞凋亡的强效诱导剂