日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Interferon gamma applied ex vivo restores function to neutrophils from critically ill patients.

体外应用γ干扰素可恢复危重病人中性粒细胞的功能。

Lake Cameron J, Scott Jonathan, Ruchaud-Sparagano Marie-Hélène, Thompson John H, Dewar Fiona, Yarova Polina, Funston Wendy, Davidson Richard Ch, Musgrave Kathryn M, Wright Stephen E, Clement Ian, Roy Alistair I, Sendama Wezi, Powell Jason, Brooks Daniel, Lin Chung Mun Alice, Davies Kristen, Hellyer Thomas P, Rostron Anthony J, Simpson A John

SHORTER trial: protocol for a pragmatic, multicentre, randomised controlled trial of short-duration antibiotic therapy for critically ill patients with sepsis

SHORTER试验:一项针对脓毒症危重患者的短期抗生素治疗的实用性、多中心、随机对照试验方案

Mawson, Phil; Morton, Miranda; Walmsley, Zoe; Wafer, Rebecca; Hancock, Helen C; Mossop, Helen; Al-Ashmori, Sarah; Emerson, Lydia M; Smith, Jamie; Colquhoun, Gosha; Wu, Hangjian; Fernandez-Garcia, Cristina; Ternent, Laura; Kumar, Rashmi; Ogden, Margaret; Loraine, Laura; Taylor, Leia; Ndlovu, Sipho; Hall, Phil; Gordon, Anthony C; Rostron, Anthony; McMullan, Ronan; Felton, Tim; Walsh, Timothy; McAuley, Daniel Francis; Dark, Paul; Simpson, A John; Hellyer, Thomas P

Primary Pulmonary NUT Carcinoma: A Case Illustration of Therapeutic Challenges and Review of Emerging Targeted Therapies

原发性肺NUT癌:治疗挑战的病例分析及新兴靶向疗法综述

Bae, Jessica Y; Gao, Xiang Yu; Dermawan, Josephine K; Hellyer, Jessica A

Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis: The ADAPT-Sepsis Randomized Clinical Trial

生物标志物指导疑似脓毒症住院患者的抗生素疗程:ADAPT-脓毒症随机临床试验

Dark, Paul; Hossain, Anower; McAuley, Daniel F; Brealey, David; Carlson, Gordon; Clayton, Jonathan C; Felton, Timothy W; Ghuman, Belinder K; Gordon, Anthony C; Hellyer, Thomas P; Lone, Nazir I; Manazar, Uzma; Richards, Gillian; McCullagh, Iain J; McMullan, Ronan; McNamee, James J; McNeil, Hannah C; Mouncey, Paul R; Naisbitt, Micheal J; Parker, Robert J; Poole, Ruth L; Rostron, Anthony J; Singer, Mervyn; Stevenson, Matt D; Walsh, Tim S; Welters, Ingeborg D; Whitehouse, Tony; Whiteley, Simon; Wilson, Peter; Young, Keith K; Perkins, Gavin D; Lall, Ranjit

Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction

新冠肺炎患者出院一年后出现的认知功能障碍是普遍存在的,并且与脑损伤标志物升高和灰质体积减少有关。

Wood, Greta K; Sargent, Brendan F; Ahmad, Zain-Ul-Abideen; Tharmaratnam, Kukatharmini; Dunai, Cordelia; Egbe, Franklyn N; Martin, Naomi H; Facer, Bethany; Pendered, Sophie L; Rogers, Henry C; Hübel, Christopher; van Wamelen, Daniel J; Bethlehem, Richard A I; Giunchiglia, Valentina; Hellyer, Peter J; Trender, William; Kalsi, Gursharan; Needham, Edward; Easton, Ava; Jackson, Thomas A; Cunningham, Colm; Upthegrove, Rachel; Pollak, Thomas A; Hotopf, Matthew; Solomon, Tom; Pett, Sarah L; Shaw, Pamela J; Wood, Nicholas; Harrison, Neil A; Miller, Karla L; Jezzard, Peter; Williams, Guy; Duff, Eugene P; Williams, Steven; Zelaya, Fernando; Smith, Stephen M; Keller, Simon; Broome, Matthew; Kingston, Nathalie; Husain, Masud; Vincent, Angela; Bradley, John; Chinnery, Patrick; Menon, David K; Aggleton, John P; Nicholson, Timothy R; Taylor, John-Paul; David, Anthony S; Carson, Alan; Bullmore, Ed; Breen, Gerome; Hampshire, Adam; Michael, Benedict D; Paddick, Stella-Maria; Leek, E Charles

Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

作者更正:CTLA4阻断可消除KEAP1/STK11相关的PD-(L)1抑制剂耐药性

Skoulidis, Ferdinandos; Araujo, Haniel A; Do, Minh Truong; Qian, Yu; Sun, Xin; Cobo, Ana Galan; Le, John T; Montesion, Meagan; Palmer, Rachael; Jahchan, Nadine; Juan, Joseph M; Min, Chengyin; Yu, Yi; Pan, Xuewen; Arbour, Kathryn C; Vokes, Natalie; Schmidt, Stephanie T; Molkentine, David; Owen, Dwight H; Memmott, Regan; Patil, Pradnya D; Marmarelis, Melina E; Awad, Mark M; Murray, Joseph C; Hellyer, Jessica A; Gainor, Justin F; Dimou, Anastasios; Bestvina, Christine M; Shu, Catherine A; Riess, Jonathan W; Blakely, Collin M; Pecot, Chad V; Mezquita, Laura; Tabbó, Fabrizio; Scheffler, Matthias; Digumarthy, Subba; Mooradian, Meghan J; Sacher, Adrian G; Lau, Sally C M; Saltos, Andreas N; Rotow, Julia; Johnson, Rocio Perez; Liu, Corinne; Stewart, Tyler; Goldberg, Sarah B; Killam, Jonathan; Walther, Zenta; Schalper, Kurt; Davies, Kurtis D; Woodcock, Mark G; Anagnostou, Valsamo; Marrone, Kristen A; Forde, Patrick M; Ricciuti, Biagio; Venkatraman, Deepti; Van Allen, Eliezer M; Cummings, Amy L; Goldman, Jonathan W; Shaish, Hiram; Kier, Melanie; Katz, Sharyn; Aggarwal, Charu; Ni, Ying; Azok, Joseph T; Segal, Jeremy; Ritterhouse, Lauren; Neal, Joel W; Lacroix, Ludovic; Elamin, Yasir Y; Negrao, Marcelo V; Le, Xiuning; Lam, Vincent K; Lewis, Whitney E; Kemp, Haley N; Carter, Brett; Roth, Jack A; Swisher, Stephen; Lee, Richard; Zhou, Teng; Poteete, Alissa; Kong, Yifan; Takehara, Tomohiro; Paula, Alvaro Guimaraes; Parra Cuentas, Edwin R; Behrens, Carmen; Wistuba, Ignacio I; Zhang, Jianjun; Blumenschein, George R; Gay, Carl; Byers, Lauren A; Gibbons, Don L; Tsao, Anne; Lee, J Jack; Bivona, Trever G; Camidge, D Ross; Gray, Jhannelle E; Leighl, Natasha B; Levy, Benjamin; Brahmer, Julie R; Garassino, Marina C; Gandara, David R; Garon, Edward B; Rizvi, Naiyer A; Scagliotti, Giorgio Vittorio; Wolf, Jürgen; Planchard, David; Besse, Benjamin; Herbst, Roy S; Wakelee, Heather A; Pennell, Nathan A; Shaw, Alice T; Jänne, Pasi A; Carbone, David P; Hellmann, Matthew D; Rudin, Charles M; Albacker, Lee; Mann, Helen; Zhu, Zhou; Lai, Zhongwu; Stewart, Ross; Peters, Solange; Johnson, Melissa L; Wong, Kwok K; Huang, Alan; Winslow, Monte M; Rosen, Michael J; Winters, Ian P; Papadimitrakopoulou, Vassiliki A; Cascone, Tina; Jewsbury, Philip; Heymach, John V

Large-scale online assessment uncovers a distinct Multiple Sclerosis subtype with selective cognitive impairment

大规模在线评估揭示了一种具有选择性认知障碍的独特多发性硬化症亚型。

Lerede, Annalaura; Moura, Alexandra; Giunchiglia, Valentina; Carta, Elisa; Trender, William; Tuite-Dalton, Katherine; Witts, James; Craig, Elaine; Knowles, Sarah; Rodgers, Jeff; Cocco, Eleonora; Hellyer, Peter J; Middleton, Rod; Nicholas, Richard; Hampshire, Adam

Remote cognitive tests predict neurodegenerative biomarkers in the Insight 46 cohort

远程认知测试可预测 Insight 46 队列中的神经退行性生物标志物

Giovane, Martina Del; Giunchiglia, Valentina; Cai, Ziyuan; Leoni, Marguerite; Street, Rebecca; Lu, Kirsty; Wong, Andrew; Popham, Maria; Nicholas, Jennifer M; Trender, William; Hellyer, Peter J; Parker, Thomas D; Murray-Smith, Heidi; Cash, David M; Barnes, Josephine; Sudre, Carole H; Malhotra, Paresh A; Crutch, Sebastian J; Richards, Marcus; Hampshire, Adam; Schott, Jonathan M

Mitigating the impact of motor impairment on self-administered digital tests: a longitudinal cohort study in stroke

减轻运动障碍对中风患者自我管理式数字测试的影响:一项纵向队列研究

Gruia, Dragos-Cristian; Giunchiglia, Valentina; Braban, Andra; Parkinson, Niamh; Banerjee, Soma; Kwan, Joseph; Hellyer, Peter J; Hampshire, Adam; Geranmayeh, Fatemeh

Structure-based discovery of positive allosteric modulators of the A(1) adenosine receptor

基于结构的A(1)腺苷受体正向变构调节剂的发现

Nguyen, Anh T N; Panel, Nicolas; Vo, Duc Duy; Thai, Bui San; Chia, Ling Yeong; Lu, Cam Sinh; Hellyer, Shane D; Langiu, Monica; Jörg, Manuela; Gregory, Karen J; Kihlberg, Jan; White, Paul J; Scammells, Peter J; Christopoulos, Arthur; Carlsson, Jens; May, Lauren T