Discovery of highly potent human glutaminyl cyclase (QC) inhibitors as anti-Alzheimer's agents by the combination of pharmacophore-based and structure-based design
通过基于药效团和基于结构的设计相结合,发现高效的人类谷氨酰胺环化酶 (QC) 抑制剂作为抗阿尔茨海默氏症药物
期刊:European Journal of Medicinal Chemistry
影响因子:6
doi:10.1016/j.ejmech.2021.113819
Nguyen Van Manh, Van-Hai Hoang, Van T H Ngo, Jihyae Ann, Tae-Ho Jang, Jung-Hye Ha, Jae Young Song, Hee-Jin Ha, Hee Kim, Young-Ho Kim, Jiyoun Lee, Jeewoo Lee