日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Nanoparticle-formulated mRNA encoding engineered multivalent SIRPα-Fc fusion proteins shows robust anti-cancer activity in preclinical models.

纳米颗粒制剂的 mRNA 编码工程化的多价 SIRPα-Fc 融合蛋白在临床前模型中显示出强大的抗癌活性

Lal Shruti, Sallets Adrienne, Bandi Srinivasa R, Adusumilli Gowrisudha, Liu Weiqun, Low Ray, Ferry Kimmy, MacDonough Chris, ElAzzouny Mahmoud, Haabeth Ole A W, McKinlay Colin J, Hsu Pei-Ken, Sharma Anushtha, Dhungel Pragyesh, Triplett Jenna, Leong Meredith, McCartney-Melstad Evan, Deutsch Samuel, Gunasekaran Kannan

Lysine-Derived Charge-Altering Releasable Transporters: Targeted Delivery of mRNA and siRNA to the Lungs

赖氨酸衍生的电荷改变可释放转运蛋白:将mRNA和siRNA靶向递送至肺部

Blake, Timothy R; Haabeth, Ole A W; Sallets, Adrienne; McClellan, Rebecca L; Del Castillo, Trevor J; Vilches-Moure, Jose G; Ho, Wilson C; Wender, Paul A; Levy, Ronald; Waymouth, Robert M

Fingolimod-Conjugated Charge-Altering Releasable Transporters Efficiently and Specifically Deliver mRNA to Lymphocytes In Vivo and In Vitro.

芬戈莫德偶联的电荷改变可释放转运体能够高效、特异性地将mRNA递送至体内和体外的淋巴细胞

Testa Stefano, Haabeth Ole A W, Blake Timothy R, Del Castillo Trevor J, Czerwinski Debra K, Rajapaksa Ranjani, Wender Paul A, Waymouth Robert M, Levy Ronald

An mRNA SARS-CoV-2 vaccine employing Charge-Altering Releasable Transporters with a TLR-9 agonist induces neutralizing antibodies and T cell memory

一种采用电荷改变释放转运体和TLR-9激动剂的mRNA SARS-CoV-2疫苗可诱导中和抗体和T细胞记忆。

Haabeth, Ole A W; Lohmeyer, Julian J K; Sallets, Adrienne; Blake, Timothy R; Sagiv-Barfi, Idit; Czerwinski, Debra K; McCarthy, Blaine; Powell, Abigail E; Wender, Paul A; Waymouth, Robert M; Levy, Ronald

Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial

自体肿瘤细胞疫苗可诱导套细胞淋巴瘤患者产生抗肿瘤T细胞免疫反应:一项I/II期试验

Frank, Matthew J; Khodadoust, Michael S; Czerwinski, Debra K; Haabeth, Ole A W; Chu, Michael P; Miklos, David B; Advani, Ranjana H; Alizadeh, Ash A; Gupta, Neel K; Maeda, Lauren S; Reddy, Sunil A; Laport, Ginna G; Meyer, Everett H; Negrin, Robert S; Rezvani, Andrew R; Weng, Wen-Kai; Sheehan, Kevin; Faham, Malek; Okada, Ami; Moore, A Holliston; Phillips, Destiny L; Wapnir, Irene L; Brody, Joshua D; Levy, Ronald

Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens

抗原呈递分析揭示了淋巴瘤免疫球蛋白新抗原的识别

Khodadoust, Michael S; Olsson, Niclas; Wagar, Lisa E; Haabeth, Ole A W; Chen, Binbin; Swaminathan, Kavya; Rawson, Keith; Liu, Chih Long; Steiner, David; Lund, Peder; Rao, Samhita; Zhang, Lichao; Marceau, Caleb; Stehr, Henning; Newman, Aaron M; Czerwinski, Debra K; Carlton, Victoria E H; Moorhead, Martin; Faham, Malek; Kohrt, Holbrook E; Carette, Jan; Green, Michael R; Davis, Mark M; Levy, Ronald; Elias, Joshua E; Alizadeh, Ash A