Therapeutic IgG- and IgM-specific proteases disarm the acetylcholine receptor autoantibodies that drive myasthenia gravis pathology
治疗性IgG和IgM特异性蛋白酶可消除驱动重症肌无力病理的乙酰胆碱受体自身抗体。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2505984122
Bayer, Alexandra C; Sanmarco, Liliana M; Pellerin, Alex; Masi, Gianvito; Plasencia, Agustin; Anderson, Jordan M; Nowak, Richard J; Damato, Valentina; Massacesi, Luca; Pham, Minh C; Khani-Habibabadi, Fatemeh; Vital, Heather; Higginson-Scott, Nathan; Otipoby, Kevin L; Xing, Yi; Mascanfroni, Ivan D; O'Connor, Kevin C