日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting the Membrane-Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

靶向膜内菱形蛋白酶GlpG：一种用于抑制剂发现和机制研究的多模式策略

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202514067
Bohg, Claudia; Dubanych, Yurii; Kosteletos, Spyridon; Xiao, Taoran; Neuenschwander, Martin; Utesch, Tillmann; Lisurek, Michael; Öster, Carl; Oder, Andreas; Seyffarth, Carola; Bach, Kathrin; Leone, Denise-Liù Gracias; Filandr, František; Wegert, Marc; Lange, Sascha; Sawczyc, Henry; von Kries, Jens Peter; Hackenberger, Christian P R; Specker, Edgar; Sun, Han; Stříšovský, Kvido; Lange, Adam
发表日期：2026
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Unsaturated Phosphorus Electrophiles to Probe Protein Tyrosine Phosphatases

利用不饱和磷亲电试剂探测蛋白质酪氨酸磷酸酶

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202521902
Poulou, Eleftheria; Ruwolt, Max; Stieger, Christian E; Kemnitz-Hassanin, Kristin; Hackenberger, Christian P R
发表日期：2026
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Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates

通过自裂解磷酰胺递送含羟基药物，扩大抗体药物偶联物的有效载荷范围

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68605-y
Ochtrop, Philipp; Jagtap, Anil P; Felber, Jan G; Vogt, Simon; Herterich, Sarah; Mai, Isabelle; Cyprys, Philipp; Schmitt, Saskia; Payer, Sarah; Kitowski, Annabel; Wunder, Swetlana; Machui, Paul; Brandmeier, Julia; Leonardi, Natascia; Poliak, Elizaveta; Hackenberger, Christian P R; Marcq, Olivier; Schumacher, Dominik; Helma, Jonas; Vogl, Annette M; Kasper, Marc-André
发表日期：2026
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Modular Vinyl Phosphonamidates for Cysteine-Directed Protein Targeting

用于半胱氨酸导向蛋白靶向的模块化乙烯基膦酰胺

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c22349
Stieger, Christian E; Völkel, Charlotte; Bertelsen, Mathias B; Lisurek, Michael; Arafiles, Jan Vincent V; Franke, Jonathan; Crocker, Leander; Schuppe, Karl; Lim, Yunjae; Groneberg, Christiane; Christmann, Mathias; Sun, Han; Hackenberger, Christian P R
发表日期：2026
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Comparative Outcomes of Two Non-Crosslinked Porcine Acellular Dermal Matrices in Complex Abdominal Wall Reconstruction: A Randomized Controlled Trial and an Observational Cohort Study

两种非交联猪源脱细胞真皮基质在复杂腹壁重建中的疗效比较：一项随机对照试验和一项观察性队列研究

期刊:World Journal of Surgery
影响因子:2.5
doi:10.1002/wjs.70271
Elemosho, Abdulaziz; Sarac, Benjamin A; Olson, Molly A; Khansa, Ibrahim; Hackenberger, Paige N; Narula, Vimal; Eiferman, Daniel S; Janis, Jeffrey E
细胞生物学
Porcine
发表日期：2026
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An engineered nanobody inhibitor for molecular-to-circuit control of opioid receptor function

一种用于从分子到回路控制阿片受体功能的工程化纳米抗体抑制剂

期刊:
影响因子:
doi:10.64898/2026.01.12.698943
Valbret, Zoé; Lamothe-Molina, Paul J; Papadogkonaki, Sofia; Koehl, Antoine; Arafiles, Jan Vincent V; Tuchman, Ziva Shapiro; Fisher, Nicole M; Radoux-Mergault, Arthur; Canziani, Annika; Huang, Gaoyang; von Zastrow, Mark; Kosloff, Mickey; Hackenberger, Christian P R; Manglik, Aashish; Patriarchi, Tommaso; Stoeber, Miriam
信号转导
发表日期：2026
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Nucleoside diphosphate kinase A (NME1) catalyses its own oligophosphorylation

核苷二磷酸激酶A (NME1) 催化自身的寡磷酸化

期刊:Nature Chemistry
影响因子:20.2
doi:10.1038/s41557-025-01915-8
Celik, Arif; Schöpf, Felix; Stieger, Christian E; Lampe, Sarah; Hanf, Björn; Morgan, Jeremy A M; Ruwolt, Max; Liu, Fan; Hackenberger, Christian P R; Roderer, Daniel; Fiedler, Dorothea
信号转导
磷酸化
发表日期：2025
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Energy-transfer photoproximity labelling in live cells using an organic cofactor

利用有机辅因子在活细胞中进行能量转移光邻近标记

期刊:Nature Chemistry
影响因子:19.2
doi:10.1038/s41557-025-01931-8.
Leander B Crocker #,Jan Vincent V Arafiles #,Judith M Müchler,Max Ruwolt,Kristin Kemnitz-Hassanin,Kilian Roßmann,Christian E Stieger,Fan Liu,Nataliya Archipowa,Roger Jan Kutta,Christian P R Hackenberger
细胞生物学
发表日期：2025
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Unsaturated Phosphine Oxides for Modular Antibody Rebridging and Single Reagent Peptide-Cyclization-Bioconjugation

用于模块化抗体重桥接和单试剂肽环化生物偶联的不饱和膦氧化物

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202508656
Stieger, Christian E; McMillan, Alastair J; de Geus, Mark A R; Arafiles, Jan Vincent V; Franz, Luise; Hackenberger, Christian P R
发表日期：2025
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Intracellular Delivery of Native Proteins by BioReversible Arginine Modification (BioRAM) on Amino Groups

通过氨基上的生物可逆精氨酸修饰（BioRAM）实现天然蛋白质的细胞内递送

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202506802
Franke, Jonathan; Arafiles, Jan Vincent V; Leis, Christian; Hackenberger, Christian P R
细胞生物学
发表日期：2025
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