日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genome-wide CRISPR screen identifies Menin and SUZ12 as regulators of human developmental timing

全基因组 CRISPR 筛选鉴定出 Menin 和 SUZ12 是人类发育时序的调控因子。

Nan Xu ,Hyein S Cho ,James O S Hackland ,Silvia Benito-Kwiecinski ,Nathalie Saurat ,Oliver Harschnitz ,Marco Vincenzo Russo ,Ralph Garippa ,Gabriele Ciceri ,Lorenz Studer

Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity

幼年特发性关节炎滑膜组织图谱揭示了与疾病严重程度相关的致病微环境

Bolton, Chrissy; Mahony, Christopher B; Clay, Elizabeth; Nisa, Patricia Reis; Lomholt, Søren; Hackland, Annie; Chin, Paulynn S; Smith, Charlotte G; Alexiou, Vicky; Nguyen, Huong D; Thyagarajan, Manigandan; Sheikh, Zishan; Davis, Penny; Chippington, Samantha; Compeyrot-Lacassagne, Sandrine; Davda, Sunit; Foley, Charlene; Turtsevich, Inga; Ingledow, Benjamin; Kupiec, Klaudia; Kelly, James; Hanlon, Megan M; DiCarlo, Edward; Jones, Luke J; Smith, Samantha L; Eyre, Stephen; Neag, Georgiana; Kemble, Samuel; Madhu, Roopa; Palshikar, Mukta G; Korsunsky, Ilya; Gao, Ce; Tran, Miles; Dendrou, Calliope; Buckley, Christopher D; Coles, Mark C; Raza, Karim; Gravallese, Ellen; Filer, Andrew; Wei, Kevin; Al-Abadi, Eslam; Rosser, Elizabeth C; Wedderburn, Lucy R; Croft, Adam P

hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease

人多能干细胞衍生的骶神经嵴能够挽救严重的先天性巨结肠症模型。

Yujie Fan ,James Hackland ,Arianna Baggiolini ,Lin Y Hung ,Huiyong Zhao ,Paul Zumbo ,Polina Oberst ,Andrew P Minotti ,Emiliano Hergenreder ,Sarah Najjar ,Zixing Huang ,Nelly M Cruz ,Aaron Zhong ,Mega Sidharta ,Ting Zhou ,Elisa de Stanchina ,Doron Betel ,Richard M White ,Michael Gershon ,Kara Gross Margolis ,Lorenz Studer

OA32 Minimally invasive, ultrasound-guided tissue biopsies of synovial tissue in children with Juvenile Idiopathic Arthritis for research: a feasibility study

OA32 微创超声引导下滑膜组织活检在幼年特发性关节炎患儿研究中的应用:一项可行性研究

Thomas, M J; Adebajo, A; Chapel, H M; Webley, M; Bolton, C; Smith, C G; McNeece, A; Sultan, S; Alexiou, V; Hackland, A; Crook, J; Nguyen, H D; Champions, Cluster; Thyagarajan, M; Shiekh, Z; Cotter, C; Nisa, P Reis; Al-Abadi, E; Chippington, S; Compeyrot-Lacassagne, S; Filer, A; Wedderburn, L; Croft, Adam

Retinoic Acid Accelerates the Specification of Enteric Neural Progenitors from In-Vitro-Derived Neural Crest

视黄酸加速体外神经嵴中肠神经祖细胞的分化

Thomas J R Frith, Antigoni Gogolou, James O S Hackland, Zoe A Hewitt, Harry D Moore, Ivana Barbaric, Nikhil Thapar, Alan J Burns, Peter W Andrews, Anestis Tsakiridis, Conor J McCann

FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision

FGF调节躯干hPSC衍生神经嵴的轴向特性,但不影响颅-躯干分化。

James O S Hackland,Patrick B Shelar,Nabjot Sandhu,Maneeshi S Prasad,Rebekah M Charney,Gustavo A Gomez,Thomas J R Frith,Martín I García-Castro

WNT/β-catenin modulates the axial identity of embryonic stem cell-derived human neural crest

WNT/β-catenin 调节胚胎干细胞衍生的人类神经嵴的轴向特征

Gustavo A Gomez, Maneeshi S Prasad, Man Wong, Rebekah M Charney, Patrick B Shelar, Nabjot Sandhu, James O S Hackland, Jacqueline C Hernandez, Alan W Leung, Martín I García-Castro

Case report: Laparoscopic totally extraperitoneal repair of an obturator hernia with self-gripping mesh under spinal anaesthesia

病例报告:在脊髓麻醉下,采用自粘网片进行腹腔镜下完全腹膜外闭孔疝修补术

Petrushnko, Wilson; Isaacs, Anna; Hackland, Tony; Ghusn, Michael

Human axial progenitors generate trunk neural crest cells in vitro

人类轴突祖细胞在体外产生躯干神经嵴细胞

Thomas Jr Frith, Ilaria Granata, Matthew Wind, Erin Stout, Oliver Thompson, Katrin Neumann, Dylan Stavish, Paul R Heath, Daniel Ortmann, James Os Hackland, Konstantinos Anastassiadis, Mina Gouti, James Briscoe, Valerie Wilson, Stuart L Johnson, Marysia Placzek, Mario R Guarracino, Peter W Andrews, A

Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells

人类胚胎干细胞中内胚层偏向性多能性亚状态的鉴定和单细胞功能表征

Allison, Thomas F; Smith, Andrew J H; Anastassiadis, Konstantinos; Sloane-Stanley, Jackie; Biga, Veronica; Stavish, Dylan; Hackland, James; Sabri, Shan; Langerman, Justin; Jones, Mark; Plath, Kathrin; Coca, Daniel; Barbaric, Ivana; Gokhale, Paul; Andrews, Peter W