日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Differential roles of Na(V)1.2 and Na(V)1.6 in neocortical pyramidal cell excitability.

Na(V)1.2 和 Na(V)1.6 在新皮层锥体细胞兴奋性中的不同作用

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.105696
Garcia Joshua D, Wang Chenyu, Alexander Ryan P D, Banks Emmie, Fenton Timothy, DeKeyser Jean-Marc, Abramova Tatiana V, George Alfred L Jr, Ben-Shalom Roy, Hackos David H, Bender Kevin J
细胞生物学
发表日期：2025
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Differential roles of Na (V) 1.2 and Na (V) 1.6 in neocortical pyramidal cell excitability

Na(V)1.2 和 Na(V)1.6 在新皮层锥体细胞兴奋性中的不同作用

期刊:
影响因子:
doi:10.1101/2024.12.17.629038
Garcia, Joshua D; Wang, Chenyu; Alexander, Ryan P D; Banks, Emmie; Fenton, Timothy; DeKeyser, Jean-Marc; Abramova, Tatiana V; George, Alfred L; Ben-Shalom, Roy; Hackos, David H; Bender, Kevin J
细胞生物学
发表日期：2025
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Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy

临床试验中的全基因组测序发现，GPR68基因中的罕见编码变异与化疗引起的周围神经病变相关。

期刊:Genome Medicine
影响因子:11.2
doi:10.1186/s13073-023-01193-4
Khan, Zia; Jung, Min; Crow, Megan; Mohindra, Rajat; Maiya, Vidya; Kaminker, Joshua S; Hackos, David H; Chandler, G Scott; McCarthy, Mark I; Bhangale, Tushar
发表日期：2023
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Cryo-EM reveals an unprecedented binding site for Na(V)1.7 inhibitors enabling rational design of potent hybrid inhibitors

冷冻电镜揭示了Na(V)1.7抑制剂前所未有的结合位点，从而能够合理设计高效的混合抑制剂。

期刊:Elife
影响因子:6.4
doi:10.7554/eLife.84151
Kschonsak, Marc; Jao, Christine C; Arthur, Christopher P; Rohou, Alexis L; Bergeron, Philippe; Ortwine, Daniel F; McKerrall, Steven J; Hackos, David H; Deng, Lunbin; Chen, Jun; Li, Tianbo; Dragovich, Peter S; Volgraf, Matthew; Wright, Matthew R; Payandeh, Jian; Ciferri, Claudio; Tellis, John C
发表日期：2023
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GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models.

GluN2A NMDA 受体增强可改善 Dravet 综合征和阿尔茨海默病模型中的脑振荡、同步性和认知功能

期刊:Cell Reports
影响因子:6.9
doi:10.1016/j.celrep.2019.12.030
Hanson Jesse E, Ma Keran, Elstrott Justin, Weber Martin, Saillet Sandrine, Khan Abdullah S, Simms Jeffrey, Liu Benjamin, Kim Thomas A, Yu Gui-Qiu, Chen Yelin, Wang Tzu-Ming, Jiang Zhiyu, Liederer Bianca M, Deshmukh Gauri, Solanoy Hilda, Chan Connie, Sellers Benjamin D, Volgraf Matthew, Schwarz Jacob B, Hackos David H, Weimer Robby M, Sheng Morgan, Gill T Michael, Scearce-Levie Kimberly, Palop Jorge J
神经科学
发表日期：2020
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TRPA1 modulation by piperidine carboxamides suggests an evolutionarily conserved binding site and gating mechanism

哌啶甲酰胺对TRPA1的调节作用表明其结合位点和门控机制在进化上是保守的。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1913929116
Chernov-Rogan, Tania; Gianti, Eleonora; Liu, Chang; Villemure, Elisia; Cridland, Andrew P; Hu, Xiaoyu; Ballini, Elisa; Lange, Wienke; Deisemann, Heike; Li, Tianbo; Ward, Stuart I; Hackos, David H; Magnuson, Steven; Safina, Brian; Klein, Michael L; Volgraf, Matthew; Carnevale, Vincenzo; Chen, Jun
RPA1
TRPA1
发表日期：2019
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TRPA1 as a drug target--promise and challenges

TRPA1作为药物靶点——前景与挑战

期刊:Naunyn-Schmiedebergs Archives of Pharmacology
影响因子:3.1
doi:10.1007/s00210-015-1088-3
Chen, Jun; Hackos, David H
RPA1
TRPA1
发表日期：2015
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