日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of novel PROS1 variants through systematic analysis of patients with suspected hereditary protein S deficiency

通过对疑似遗传性蛋白S缺乏症患者的系统分析,鉴定出新的PROS1变异体。

Magosi, Lerato E; Tchetgen, Eric Tchetgen; Novitsky, Vlad; Pretorius Holme, Molly; Moore, Janet; Bachanas, Pam; Lebelonyane, Refeletswe; Fraser, Christophe; Moyo, Sikhulile; Hurwitz, Kathleen E; Gaolathe, Tendani; Goyal, Ravi; Makhema, Joseph; Lockman, Shahin; Essex, Max; De Gruttola, Victor; Lipsitch, Marc; Bartylla, Malte M; Achenbach, Susanne; Hackstein, Holger; Schneider, Sabine

NK cell-mediated tumor cell killing by bispecific innate cell engagers induces ADCC-mediated activation of primary human dendritic cells

双特异性固有免疫细胞衔接器介导的NK细胞杀伤肿瘤细胞可诱导ADCC介导的原代人树突状细胞活化。

Heger, Lukas; Kaszubowski, Tomasz; Amon, Lukas; Lehmann, Christian H K; Wingert, Susanne; Medina-Echeverz, José; Koch, Joachim; Hackstein, Holger; Purbojo, Ariawan; Hartmann, Arndt; Alexiou, Christoph; Cesnjevar, Robert; Pahl, Jens; Dudziak, Diana

Precursors of exhausted T cells are pre-emptively formed in acute infection

在急性感染中,耗竭T细胞的前体细胞会预先形成。

Chu, Talyn; Wu, Ming; Hoellbacher, Barbara; de Almeida, Gustavo P; Wurmser, Christine; Berner, Jacqueline; Donhauser, Lara V; Gerullis, Ann-Katrin; Lin, Siran; Cepeda-Mayorga, J Diego; Kilb, Iman I; Bongers, Lukas; Toppeta, Fabio; Strobl, Philipp; Youngblood, Ben; Schulz, Anna M; Zippelius, Alfred; Knolle, Percy A; Heinig, Matthias; Hackstein, Carl-Philipp; Zehn, Dietmar

Rapid clinical effects of convalescent plasma therapy in severe COVID-19 acute respiratory distress syndrome (ARDS)

康复者血浆疗法对重症 COVID-19 急性呼吸窘迫综合征 (ARDS) 的快速临床疗效

Bihlmaier, Karl; Willam, Carsten; Herbst, Larissa; Hackstein, Holger; Schiffer, Mario

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines.

MAIT 和其他先天样 T 细胞整合适应性免疫反应,以调节对 mRNA 疫苗的间隔依赖性反应原性。

Amini Ali, Garner Lucy C, Shaw Robert H, Kelly Neil Wrigley, Adele Sandra, Skelly Donal T, Dejnirattisai Wanwisa, Greenland Melanie, Liu Xinxue, Heslington Amelia, Hackstein Carl-Philipp, Murray Sam M, Vano Cristina Riquelme, Stafford Lizzie, Johnson Sile, Sayaf Katia, Pudjohartono Maria Fransiska, Clutterbuck Elizabeth A, Bibi Sagida, Conlon Christopher P, James Tim, Jeffery Katie, Kronsteiner Barbara, Mentzer Alexander J, O'Shea Donal, Ramasamy Maheshi N, Screaton Gavin R, Snape Matthew D, Hogan Andrew E, Barnes Eleanor, Lambe Teresa, Dunachie Susanna J, Provine Nicholas M, Klenerman Paul

SwitchTFI: identifying transcription factors driving cell differentiation

SwitchTFI:识别驱动细胞分化的转录因子

Martini, Paul; Hartebrodt, Anne; de Almeida, Gustavo P; Hackstein, Carl-Philipp; Zehn, Dietmar; Blumenthal, David B

Extracorporeal photopheresis reduces the T cell stimulatory capacity of human primary blood conventional dendritic cells type 1

体外光疗降低了人原代血液常规树突状细胞1型T细胞的刺激能力

Lukas Heger ,Carola Berking ,Holger Hackstein

CD40 blockade hampers IgG class-switch while enhancing Granzyme B production by transitional B cells

CD40阻断会抑制IgG类别转换,同时增强过渡B细胞产生颗粒酶B。

Felix Werner ,Jens Wittner ,Christian H K Lehmann ,Mandy Wahlbuhl ,Ida Allabauer ,Adrian Hoffmann ,Alexander Schnell ,Tobias Krickau ,Holger Hackstein ,Barbara Dietel-Schor ,James S Rush ,Catherine H Regnier ,Hans-Martin Jäck ,Joachim Woelfle ,Wolfgang Schuh ,André Hoerning

Influence of the Immune Checkpoint Inhibitors on the Hemostatic Potential of Blood Plasma

免疫检查点抑制剂对血浆止血潜能的影响

Patalakh, Irina; Wandersee, Alexandra; Schlüter, Julian; Erdmann, Michael; Hackstein, Holger; Cunningham, Sarah

HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation

HLA-C*04:09N 在细胞表面表达,并触发肽特异性 T 细胞活化。

Carlotta Welters ,Marthe-Lina Welters ,Serena Stadler ,Lars Bullinger ,Julian Strobel ,Holger Hackstein ,Arunraj Dhamodaran ,Thomas Blankenstein ,Leo Hansmann