Phosphorylation of PP2Ac by PKC is a key regulatory step in the PP2A-switch-dependent AKT dephosphorylation that leads to apoptosis
PKC 对 PP2Ac 的磷酸化是 PP2A 开关依赖性 AKT 去磷酸化的关键调节步骤,可导致细胞凋亡
期刊:Cell Communication and Signaling
影响因子:8.2
doi:10.1186/s12964-024-01536-7
Guy Nadel #, Zhong Yao #, Avital Hacohen-Lev-Ran, Ehud Wainstein, Galia Maik-Rachline, Tamar Ziv, Zvi Naor, Arie Admon, Rony Seger
信号转导
细胞生物学
表观遗传
其它细胞
Apoptosis
PI3K/Akt