日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Imidazole as a Pendant Reactivation Ligand Increases Efficacy Scope for Reactivation and Resurrection of Organophosphorus-Inhibited/Aged Cholinesterases by Quinone Methide Precursors

咪唑作为侧链复活配体可提高醌甲化物前体对有机磷抑制/老化胆碱酯酶的复活和活化的功效范围

Lovins, Alex R; Miller, Kevin A; Homoelle, Rose K; Hoover, Hayden J; McElroy, Craig A; Callam, Christopher S; Hadad, Christopher M

Dendritic Pillar[6]Arenes with Fixed Planar Chirality for Stereoselective Inclusions in Water: A Case of Facile Differentiation of Cocaine Adulterants, Levamisole and Dexamisole

具有固定平面手性的树枝状柱状[6]芳烃在水中的立体选择性包合:可卡因掺杂物左旋咪唑和右旋咪唑简易鉴别的案例

Kumar, Nitesh; Karmakar, Pratik; Politeski, Matthew D; Hansen, Alexandar R; Ward, Carson E; Mortensen, Christopher; Hadad, Christopher M; Pratumyot, Kornkanya; Badjić, Jovica D

Correction: Molecular bowls for inclusion complexation of toxic anticancer drug methotrexate

更正:用于包合有毒抗癌药物甲氨蝶呤的分子碗

Karmakar, Pratik; Finnegan, Tyler J; Rostam, Darian C; Taneja, Sagarika; Uçar, Sefa; Hansen, Alexandar L; Moore, Curtis E; Hadad, Christopher M; Pratumyot, Kornkanya; Parquette, Jon R; Badjić, Jovica D

Development and Characterization of pFluor50, a Fluorogenic-Based Kinetic Assay System for High-Throughput Inhibition Screening and Characterization of Time-Dependent Inhibition and Inhibition Type for Six Human CYPs.

pFluor50 的开发和表征,一种基于荧光的动力学分析系统,用于高通量抑制筛选和表征六种人类 CYP 的时间依赖性抑制和抑制类型

Shriwas Pratik, Revnew Andre, Roo Sarah, Bender Alex, Miller Kevin, Hadad Christopher M, Lane Thomas R, Ekins Sean, McElroy Craig A

Human CYP2C9 Metabolism of Organophosphorus Pesticides and Nerve Agent Surrogates

人体CYP2C9对有机磷农药和神经毒剂类似物的代谢

Shriwas, Pratik; Noonchester, Abigail M; Revnew, Andre; Lane, Thomas R; Hadad, Christopher M; Ekins, Sean; McElroy, Craig A

Molecular docking and biological evaluation of a novel IWS1 inhibitor for the treatment of human retroperitoneal liposarcoma.

新型 IWS1 抑制剂治疗人类腹膜后脂肪肉瘤的分子对接和生物学评价

Goryunova Marina, He Yiran, Karakis Carson, Titerina Elizaveta K, Salazar-Puerta Ana I, Tahara Sayumi, Sp Nipin, Thakkar Neil N, Cómbita-Heredia Orlando, Dathathreya Kavya, La Ferlita Alessandro, Xu Yanping, Zhang Zhentao, Pollock Raphael, Gallego-Perez Daniel, Zhu Hua, Hadad Christopher M, Beane Joal D

Aza-peptide aldehydes and ketones: synthesis and evaluation as human 20S proteasome inhibitors

氮杂肽醛和酮:合成及作为人20S蛋白酶体抑制剂的评价

Corrigan, Thomas S; Border, Sarah E; Lotti Diaz, Leilani M; Kasper, Kayla Q; Noonchester, Abigail M; Amer, Rasmiah; Kucway, Kayla S; Fleisher, Michael; Fernandez, Joseph P; Lovins, Alex R; Serrano, Ana K; Caffrey, Conor R; O'Donoghue, Anthony J; Benson, Don M Jr; Hadad, Christopher M; Ekici, Özlem Doğan

Molecular bowls for inclusion complexation of toxic anticancer drug methotrexate

用于包合有毒抗癌药物甲氨蝶呤的分子碗

Karmakar, Pratik; Finnegan, Tyler J; Rostam, Darian C; Taneja, Sagarika; Uçar, Sefa; Hansen, Alexandar L; Moore, Curtis E; Hadad, Christopher M; Pratumyot, Kornkanya; Parquette, Jon R; Badjić, Jovica D

Highly Enantioselective Catalytic Alkynylation of Quinolones: Substrate Scope, Mechanistic Studies, and Applications in the Syntheses of Chiral N-Heterocyclic Alkaloids and Diamines

喹诺酮的高对映选择性催化炔基化反应:底物范围、机理研究及其在手性N-杂环生物碱和二胺合成中的应用

Guan, Yong; Buivydas, Tadas A; Lalisse, Remy F; Laybourn, Kalen B; Stern, Charlotte; Richins, Margaret; Burns, Sean M; Shelby, Arielle; Hadad, Christopher M; Mattson, Anita E

Robust, Enantioselective Construction of Challenging, Biologically Relevant Tertiary Ether Stereocenters

稳健、对映选择性地构建具有挑战性的、具有生物学意义的叔醚立体中心

Guan, Yong; Buivydas, Tadas A; Lalisse, Remy F; Attard, Jonathan W; Ali, Rameez; Stern, Charlotte; Hadad, Christopher M; Mattson, Anita E