日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery of small molecules against porcine reproductive and respiratory syndrome virus replication by targeting NendoU activity.

通过靶向 NendoU 活性发现针对猪繁殖与呼吸综合征病毒复制的小分子

Zhu Jiaqi, Lai Yunqiang, Cheng Mengqi, Dash Radha Charan, Guo Shuangshuang, Guo Jintong, Su Yue, Wolek Andrew, Issacs Brianna, Liu Zhenming, Li Qi, Mishra Neha, Garmendia Antonio, Hadden M Kyle, Tian X Cindy, He Xin, Tang Young

Probing hot spots of protein-protein interactions mediated by the safety-belt region of REV7.

探究由 REV7 安全带区域介导的蛋白质-蛋白质相互作用热点

Dash Radha Charan, Arianna Gianluca A, Patel Seema M, Rizzo Alessandro A, Harrahill Noah J, Korzhnev Dmitry M, Hadden M Kyle

Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction.

REV1-CT/RIR 跨损伤合成蛋白-蛋白相互作用的小分子抑制剂先导化合物分析

Zaino Angela M, Dash Radha Charan, James Stephy J, MacGilvary Nathan, Crompton Andrew, McPherson Kerry S, Stanzione Marcello, Korzhnev Dmitry M, Dyson Nicholas J, Chatterjee Nimrat, Cantor Sharon B, Hadden M Kyle

Translesion synthesis inhibitors as a new class of cancer chemotherapeutics

跨损伤合成抑制剂作为一类新型癌症化疗药物

Patel, Seema M; Dash, Radha Charan; Hadden, M Kyle

Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis

基于结构的菲那吡啶衍生物药物设计及其作为Rev1相互作用抑制剂在跨损伤合成中的应用

McPherson, Kerry Silva; Zaino, Angela M; Dash, Radha C; Rizzo, Alessandro A; Li, Yunfeng; Hao, Bing; Bezsonova, Irina; Hadden, M Kyle; Korzhnev, Dmitry M

Formulation and evaluation of itraconazole liposomes for Hedgehog pathway inhibition

伊曲康唑脂质体的制备及Hedgehog信号通路抑制的评价

Pace, Jennifer R; Jog, Rajan; Burgess, Diane J; Hadden, M Kyle

Virtual Pharmacophore Screening Identifies Small-Molecule Inhibitors of the Rev1-CT/RIR Protein-Protein Interaction

虚拟药效团筛选鉴定出Rev1-CT/RIR蛋白-蛋白相互作用的小分子抑制剂

Dash, Radha C; Ozen, Zuleyha; McCarthy, Kaitlyn R; Chatterjee, Nimrat; Harris, Cynthia A; Rizzo, Alessandro A; Walker, Graham C; Korzhnev, Dmitry M; Hadden, M Kyle

Identification of Small Molecule Translesion Synthesis Inhibitors That Target the Rev1-CT/RIR Protein-Protein Interaction

鉴定靶向 Rev1-CT/RIR 蛋白-蛋白相互作用的小分子跨损伤合成抑制剂

Sail, Vibhavari; Rizzo, Alessandro A; Chatterjee, Nimrat; Dash, Radha C; Ozen, Zuleyha; Walker, Graham C; Korzhnev, Dmitry M; Hadden, M Kyle

Cytotoxic small molecule dimers and their inhibitory activity against human breast cancer cells

细胞毒性小分子二聚体及其对人乳腺癌细胞的抑制活性

Hadden, M Kyle; Blagg, Brian S J