日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Efficacy of the Antibody-Drug Conjugate W0101 in Preclinical Models of IGF-1 Receptor Overexpressing Solid Tumors

抗体-药物偶联物 W0101 在 IGF-1 受体过度表达实体瘤临床前模型中的疗效

Barbara Akla, Matthieu Broussas, Noureddine Loukili, Alain Robert, Charlotte Beau-Larvor, Martine Malissard, Nicolas Boute, Thierry Champion, Jean-Francois Haeuw, Alain Beck, Michel Perez, Cyrille Dreyfus, Mariya Pavlyuk, Eric Chetaille, Nathalie Corvaia

A sensitive multidimensional method for the detection, characterization, and quantification of trace free drug species in antibody-drug conjugate samples using mass spectral detection

一种利用质谱检测技术对抗体-药物偶联物样品中痕量游离药物进行检测、表征和定量分析的灵敏多维方法

Birdsall, Robert E; McCarthy, Sean M; Janin-Bussat, Marie Claire; Perez, Michel; Haeuw, Jean-François; Chen, Weibin; Beck, Alain

Antibody-drug conjugate model fast characterization by LC-MS following IdeS proteolytic digestion

利用IdeS蛋白酶消化后通过LC-MS快速表征抗体-药物偶联物模型

Wagner-Rousset, Elsa; Janin-Bussat, Marie-Claire; Colas, Olivier; Excoffier, Melissa; Ayoub, Daniel; Haeuw, Jean-François; Rilatt, Ian; Perez, Michel; Corvaïa, Nathalie; Beck, Alain

Protective levels of polysaccharide-specific maternal antibodies may enhance the immune response elicited by pneumococcal conjugates in neonatal and infant mice

母体中多糖特异性抗体的保护水平可能增强新生小鼠和幼鼠对肺炎球菌结合物的免疫反应。

Richter, Margret Y; Jakobsen, Havard; Haeuw, Jean-François; Power, Ultan F; Jonsdottir, Ingileif

Immunization of female mice with glycoconjugates protects their offspring against encapsulated bacteria

用糖缀合物免疫雌性小鼠可保护其后代免受荚膜细菌的感染。

Richter, Margret Y; Jakobsen, Håvard; Birgisdottir, Alda; Haeuw, Jean-François; Power, Ultan F; Del Giudice, Giuseppe; Bartoloni, Antonella; Jonsdottir, Ingileif

Identification of B- and T-cell epitopes of BB, a carrier protein derived from the G protein of Streptococcus strain G148.

鉴定链球菌 G148 株 G 蛋白衍生的载体蛋白 BB 的 B 细胞和 T 细胞表位

Goetsch Liliane, Haeuw Jean Francois, Champion Thierry, Lacheny Christine, N'Guyen Thien, Beck Alain, Corvaia Nathalie

CD4(+) T-cell-mediated antiviral protection of the upper respiratory tract in BALB/c mice following parenteral immunization with a recombinant respiratory syncytial virus G protein fragment

重组呼吸道合胞病毒 G 蛋白片段肠外免疫后 BALB/c 小鼠上呼吸道 CD4(+) T 细胞介导的抗病毒保护作用

H Plotnicky-Gilquin, A Robert, L Chevalet, J F Haeuw, A Beck, J Y Bonnefoy, C Brandt, C A Siegrist, T N Nguyen, U F Power

Identification of multiple protective epitopes (protectopes) in the central conserved domain of a prototype human respiratory syncytial virus G protein

在人类呼吸道合胞病毒原型G蛋白的中心保守结构域中鉴定出多个保护性表位(保护表位)

Plotnicky-Gilquin, H; Goetsch, L; Huss, T; Champion, T; Beck, A; Haeuw, J F; Nguyen, T N; Bonnefoy, J Y; Corvaïa, N; Power, U F

The core-specific lysosomal alpha(1-6)-mannosidase activity depends on aspartamidohydrolase activity

核心特异性溶酶体α(1-6)-甘露糖苷酶活性依赖于天冬酰胺水解酶活性。

Haeuw, J F; Grard, T; Alonso, C; Strecker, G; Michalski, J C