日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Low overlap of transcription factor DNA binding and regulatory targets

转录因子DNA结合位点与调控靶点的重叠度较低

Mahendrawada, Lakshmi; Warfield, Linda; Donczew, Rafal; Hahn, Steven

Transcriptional noise, gene activation, and roles of SAGA and Mediator Tail measured using nucleotide recoding single-cell RNA-seq.

利用核苷酸重编码单细胞 RNA-seq 测量转录噪声、基因激活以及 SAGA 和 Mediator Tail 的作用

Schofield Jeremy A, Hahn Steven

Mediator subunit Med15 dictates the conserved "fuzzy" binding mechanism of yeast transcription activators Gal4 and Gcn4

介导亚基Med15决定了酵母转录激活因子Gal4和Gcn4的保守“模糊”结合机制。

Tuttle, Lisa M; Pacheco, Derek; Warfield, Linda; Wilburn, Damien B; Hahn, Steven; Klevit, Rachel E

A High-Throughput Screen for Transcription Activation Domains Reveals Their Sequence Features and Permits Prediction by Deep Learning

高通量筛选转录激活域揭示其序列特征并允许通过深度学习进行预测

Erijman, Ariel; Kozlowski, Lukasz; Sohrabi-Jahromi, Salma; Fishburn, James; Warfield, Linda; Schreiber, Jacob; Noble, William S; Söding, Johannes; Hahn, Steven

ATM Loss Confers Greater Sensitivity to ATR Inhibition Than PARP Inhibition in Prostate Cancer

在前列腺癌中,ATM 缺失使 ATR 抑制比 PARP 抑制具有更高的敏感性

Shahrzad Rafiei, Kenyon Fitzpatrick, David Liu, Mu-Yan Cai, Haitham A Elmarakeby, Jihye Park, Cora Ricker, Bose S Kochupurakkal, Atish D Choudhury, William C Hahn, Steven P Balk, Justin H Hwang, Eliezer M Van Allen, Kent W Mouw

Characteristics and Outcomes of In-Hospital Cardiac Arrest Events During the COVID-19 Pandemic: A Single-Center Experience From a New York City Public Hospital

COVID-19 大流行期间院内心脏骤停事件的特征和结果:纽约市一家公立医院的单中心经验

Miles, Jeremy A; Mejia, Mateo; Rios, Saul; Sokol, Seth I; Langston, Matthew; Hahn, Steven; Leiderman, Ephraim; Salgunan, Reka; Soghier, Israa; Gulani, Perminder; Joshi, Keval; Chung, Virginia; Morante, Joaquin; Maggiore, Diane; Uppal, Dipan; Friedman, Ari; Katamreddy, Adarsh; Abittan, Nathaniel; Ramani, Gokul; Irfan, Wakil; Liaqat, Wasla; Grushko, Michael; Krouss, Mona; Cho, Hyung J; Bradley, Steven M; Faillace, Robert T

Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma

双重 BET/HDAC 抑制剂治疗胰腺导管腺癌的表征

Xin Zhang, Tim Zegar, Tim Weiser, Feda H Hamdan, Benedict-Tilman Berger, Romain Lucas, Dimitrios-IIias Balourdas, Swetlana Ladigan, Phyllis F Cheung, Sven-Thorsten Liffers, Marija Trajkovic-Arsic, Bjoern Scheffler, Andreas C Joerger, Stephan A Hahn, Steven A Johnsen, Stefan Knapp, Jens T Siveke

Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex

Gcn4-介导因子特异性由一个大型且动态的模糊蛋白-蛋白复合物介导。

Tuttle, Lisa M; Pacheco, Derek; Warfield, Linda; Luo, Jie; Ranish, Jeff; Hahn, Steven; Klevit, Rachel E

Mechanistic Differences in Transcription Initiation at TATA-Less and TATA-Containing Promoters

无TATA盒启动子和含TATA盒启动子转录起始机制的差异

Donczew, Rafal; Hahn, Steven

Transcription Activation Domains of the Yeast Factors Met4 and Ino2: Tandem Activation Domains with Properties Similar to the Yeast Gcn4 Activator

酵母因子 Met4 和 Ino2 的转录激活结构域:具有与酵母 Gcn4 激活因子相似特性的串联激活结构域

Pacheco, Derek; Warfield, Linda; Brajcich, Michelle; Robbins, Hannah; Luo, Jie; Ranish, Jeff; Hahn, Steven