Functional differences between CLL- and ALL-derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL-10 as potential modulatory targets.
CLL 和 ALL 来源的 CAR T 细胞在 3D 肿瘤微环境中的功能差异凸显了 CXCR4 和 IL-10 作为潜在的调节靶点。
期刊:Hemasphere
影响因子:14.6
doi:10.1002/hem3.70279
Dingfelder Janin, Aigner Michael, Lindacher Jana, Lukas Pascal, Flamann Cindy, Nusser Gina, Zimmermann Katharina, Schambach Axel, Graw Frederik, Völkl Simon, Bruns Heiko, Krumbholz Manuela, Haibach Martina, Wilke Jochen, Mackensen Andreas, Lutzny-Geier Gloria
