日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Programming tumor evolution with selection gene drives to proactively combat drug resistance

利用选择基因驱动程序控制肿瘤进化,以主动对抗耐药性

Scott M Leighow ,Joshua A Reynolds ,Ivan Sokirniy ,Shun Yao ,Zeyu Yang ,Haider Inam ,Dominik Wodarz ,Marco Archetti ,Justin R Pritchard

A side-by-side comparison of variant function measurements using deep mutational scanning and base editing

使用深度突变扫描和碱基编辑对变异功能测量进行并排比较

Ivan Sokirniy, Haider Inam, Marta Tomaszkiewicz, Joshua Reynolds, David McCandlish, Justin Pritchard

Excessive concentrations of kinase inhibitors in translational studies impede effective drug repurposing

转化研究中激酶抑制剂浓度过高阻碍了有效的药物再利用

Chuan Liu, Scott M Leighow, Kyle McIlroy, Mengrou Lu, Kady A Dennis, Kerry Abello, Donovan J Brown, Connor J Moore, Anushka Shah, Haider Inam, Victor M Rivera, Justin R Pritchard

Genomic and experimental evidence that ALKATI does not predict single agent sensitivity to ALK inhibitors

基因组学和实验证据表明 ALKATI 不能预测单药对 ALK 抑制剂的敏感性

Haider Inam, Ivan Sokirniy, Yiyun Rao, Anushka Shah, Farnaz Naeemikia, Edward O'Brien, Cheng Dong, David M McCandlish, Justin R Pritchard

Multi-scale Predictions of Drug Resistance Epidemiology Identify Design Principles for Rational Drug Design

耐药流行病学的多尺度预测确定合理药物设计的设计原则

Scott M Leighow, Chuan Liu, Haider Inam, Boyang Zhao, Justin R Pritchard