TRIM64 promotes ox-LDL-induced foam cell formation, pyroptosis, and inflammation in THP-1-derived macrophages by activating a feedback loop with NF-κB via IκBα ubiquitination
TRIM64通过IκBα泛素化激活与NF-κB的反馈环路，促进ox-LDL诱导的THP-1来源巨噬细胞的泡沫细胞形成、细胞焦亡和炎症。
期刊:Cell Biology and Toxicology
影响因子:5.3
doi:10.1007/s10565-022-09768-4
Chao Zhu #,Wei Chen #,Haiming Cui,Zhigang Huang,Ru Ding,Na Li,Qinqin Wang,Feng Wu,Yanmin Zhao,Xiaoliang Cong
细胞生物学
炎症/感染
表观遗传
巨噬细胞
NF-κB
炎症
巨噬细胞
泛素化
焦亡
