日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural mechanisms of allosteric regulation in the human cis-prenyltransferase complex

人类顺式异戊二烯基转移酶复合物变构调节的结构机制

Giladi, Moshe; Kredi, Shiri; Guardiani, Carlo; Aviram, Lyr; Vaňková, Pavla; Gaizinger, Yarin; Man, Petr; Giacomello, Alberto; Haitin, Yoni

Identifying and quantifying membrane interactions of the protein human cis-prenyltransferase

鉴定和定量人顺式异戊二烯基转移酶蛋白的膜相互作用

Boren, Duncan M; Kredi, Shiri; Positselskaya, Ekaterina; Giladi, Moshe; Haitin, Yoni; Vermaas, Josh V

Mono-allelic p.R37H Dehydrodolichyl Diphosphate Synthase variants lead to protein glycosylation defects, aberrant lipid profiles and interneuron scarcity in a novel mouse model of progressive epileptic encephalopathy

单等位基因 p.R37H 脱氢多萜醇二磷酸合成酶变体导致进行性癫痫性脑病的新型小鼠模型出现蛋白质糖基化缺陷、异常脂质谱和中间神经元稀少。

Da Silva, Afitz; Tene Tadoum, Samuel Boris; Muffels, Irena J J; Budhraja, Rohit; Sturiale, Luisa; Messina, Angela; Giladi, Moshe; Taherzadeh, Mahsa; Fazeli, Mehrnaz; Bonneil, Éric; Khan, Shaukat; Te Vruchte, Danielle; Yamanaka, Yojiro; Di Cristo, Graziella; Hamdan, Fadi F; Platt, Frances M; Tomatsu, Shunji; Haitin, Yoni; Kozicz, Tamas; Thibault, Pierre; Garozzo, Domenico; Pandey, Akilesh; Morava, Eva; Rossignol, Elsa; Pshezhetsky, Alexey V

A somatic multiple myeloma mutation unravels a mechanism of oligomerization-mediated product inhibition in GGPPS

体细胞多发性骨髓瘤突变揭示了GGPPS中寡聚化介导的产物抑制机制

Yehia, Ruba; Portašiková, Jasmína Mária; Mor Yosef, Rut; Da'adoosh, Benny; Kádek, Alan; Man, Petr; Giladi, Moshe; Haitin, Yoni

Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels

活细胞定量监测揭示了Gβγ对GIRK2和GIRK1/2通道的不同高亲和力调控作用

Handklo-Jamal, Reem; Raifman, Tal Keren; Shalomov, Boris; Hofer, Patrick; Kahanovitch, Uri; Friesacher, Theres; Tabak, Galit; Tsemakhovich, Vladimir; Reddy, Haritha P; Chomsky-Hecht, Orna; Tripathy, Debi Ranjan; Zuhlke, Kerstin; Dessauer, Carmen W; Klussmann, Enno; Haitin, Yoni; Hirsch, Joel A; Stary-Weinzinger, Anna; Yakubovich, Daniel; Dascal, Nathan

Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels

活细胞定量监测揭示了Gβγ对GIRK2和GIRK1/2通道的不同高亲和力调控作用

Handklo-Jamal, Reem; Raifman, Tal Keren; Shalomov, Boris; Hofer, Patrick; Kahanovitch, Uri; Friesacher, Theres; Tabak, Galit; Tsemakhovich, Vladimir; Reddy, Haritha P; Chomsky-Hecht, Orna; Tripathy, Debi Ranjan; Zuhlke, Kerstin; Dessauer, Carmen W; Klussmann, Enno; Haitin, Yoni; Hirsch, Joel A; Stary-Weinzinger, Anna; Yakubovich, Daniel; Dascal, Nathan

Identification of a magnesium-binding site at the primary allosteric calcium sensor of the sodium-calcium exchanger: Implications for physiological regulation

鉴定钠钙交换器主要变构钙传感器上的镁结合位点:对生理调节的意义

Manori, Bar; Da'adoosh, Benny; Haitin, Yoni; Giladi, Moshe

Structural basis for long-chain isoprenoid synthesis by cis-prenyltransferases

顺式异戊二烯基转移酶合成长链异戊二烯的结构基础

Giladi, Moshe; Lisnyansky Bar-El, Michal; Vaňková, Pavla; Ferofontov, Alisa; Melvin, Emelia; Alkaderi, Suha; Kavan, Daniel; Redko, Boris; Haimov, Elvira; Wiener, Reuven; Man, Petr; Haitin, Yoni

Ultrasensitive chemiluminescent neuraminidase probe for rapid screening and identification of small-molecules with antiviral activity against influenza A virus in mammalian cells

用于快速筛选和鉴定哺乳动物细胞中具有抗甲型流感病毒活性的小分子的超灵敏化学发光神经氨酸酶探针

Shelef, Omri; Gutkin, Sara; Feder, Daniel; Ben-Bassat, Ariel; Mandelboim, Michal; Haitin, Yoni; Ben-Tal, Nir; Bacharach, Eran; Shabat, Doron

TTYH family members form tetrameric complexes at the cell membrane

TTYH 家族成员在细胞膜上形成四聚体复合物

Emelia Melvin, Zuzana Kalaninová, Elia Shlush, Petr Man, Moshe Giladi, Yoni Haitin