日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Broad repression of DNA repair genes in senescent cells identified by integration of transcriptomic data

通过整合转录组数据,发现衰老细胞中DNA修复基因普遍受到抑制。

Frey, Yann; Haj, Majd; Ziv, Yael; Elkon, Ran; Shiloh, Yosef

ZC3H4 safeguards genome integrity by preventing transcription-replication conflicts at noncoding RNA loci.

ZC3H4 通过防止非编码 RNA 位点的转录-复制冲突来保护基因组完整性

Frey Yann, Goehring Liana, Haj Majd, Rona Gergely, Fijen Carel, Pagano Michele, Huang Tony T, Rothenberg Eli, Ziv Yael, Shiloh Yosef

The cGAS-STING, p38 MAPK, and p53 pathways link genome instability to accelerated cellular senescence in ATM-deficient murine lung fibroblasts

cGAS-STING、p38 MAPK 和 p53 通路将基因组不稳定性与 ATM 缺陷小鼠肺成纤维细胞的加速衰老联系起来。

Haj, Majd; Frey, Yann; Levon, Amit; Maliah, Avishai; Ben-Yishay, Tal; Slutsky, Rachel; Smoom, Riham; Tzfati, Yehuda; Ben-David, Uri; Levy, Carmit; Elkon, Ran; Ziv, Yael; Shiloh, Yosef

Accelerated replicative senescence of ataxia-telangiectasia skin fibroblasts is retained at physiologic oxygen levels, with unique and common transcriptional patterns

共济失调毛细血管扩张症皮肤成纤维细胞的加速复制性衰老在生理氧水平下仍然存在,并具有独特和共同的转录模式。

Haj, Majd; Levon, Amit; Frey, Yann; Hourvitz, Noa; Campisi, Judith; Tzfati, Yehuda; Elkon, Ran; Ziv, Yael; Shiloh, Yosef