日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment

代谢灵活性决定了人类 NK 细胞在肿瘤微环境中的功能命运

Sophie M Poznanski, Kanwaldeep Singh, Tyrah M Ritchie, Jennifer A Aguiar, Isabella Y Fan, Ana L Portillo, Eduardo A Rojas, Fatemeh Vahedi, Abdullah El-Sayes, Sansi Xing, Martin Butcher, Yu Lu, Andrew C Doxey, Jonathan D Schertzer, Hal W Hirte, Ali A Ashkar

Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors

口服MDM2拮抗剂idasanutlin每日和每周给药方案治疗晚期肿瘤患者的I期研究

Italiano, Antoine; Miller, Wilson H Jr; Blay, Jean-Yves; Gietema, Jourik A; Bang, Yung-Jue; Mileshkin, Linda R; Hirte, Hal W; Higgins, Brian; Blotner, Steven; Nichols, Gwen L; Chen, Lin Chi; Petry, Claire; Yang, Qi Joy; Schmitt, Christophe; Jamois, Candice; Siu, Lillian L

A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer

一项随机II期临床试验,研究表观遗传学启动联合卡铂治疗铂耐药复发性卵巢癌的疗效

Oza, Amit M; Matulonis, Ursula A; Alvarez Secord, Angeles; Nemunaitis, John; Roman, Lynda D; Blagden, Sarah P; Banerjee, Susana; McGuire, William P; Ghamande, Sharad; Birrer, Michael J; Fleming, Gini F; Markham, Merry Jennifer; Hirte, Hal W; Provencher, Diane M; Basu, Bristi; Kristeleit, Rebecca; Armstrong, Deborah K; Schwartz, Benjamin; Braly, Patricia; Hall, Geoff D; Nephew, Kenneth P; Jueliger, Simone; Oganesian, Aram; Naim, Sue; Hao, Yong; Keer, Harold; Azab, Mohammad; Matei, Daniela

Phase II Trial of Cabozantinib in Recurrent/Metastatic Endometrial Cancer: A Study of the Princess Margaret, Chicago, and California Consortia (NCI9322/PHL86)

卡博替尼治疗复发/转移性子宫内膜癌的 II 期试验:玛格丽特公主、芝加哥和加利福尼亚联盟的研究 (NCI9322/PHL86)

Dhani, Neesha C; Hirte, Hal W; Wang, Lisa; Burnier, Julia V; Jain, Angela; Butler, Marcus O; Welch, Stephen; Fleming, Gini F; Hurteau, Jean; Matsuo, Koji; Matei, Daniela; Jimenez, Waldo; Johnston, Carolyn; Cristea, Mihaela; Tonkin, Katia; Ghatage, Prafull; Lheureux, Stephanie; Mehta, Anjali; Quintos, Judy; Tan, Qian; Kamel-Reid, Suzanne; Ludkovski, Olga; Tsao, Ming-Sound; Wright, John J; Oza, Amit M

Bullous vesicant-type reaction to docetaxel along the venous tract: A case report

多西他赛沿静脉通路引起的疱疹样反应:病例报告

Su, Jane; Bernard, Laurence; Colantonio, Sophia; Norgaard, Alexander; Hirte, Hal W; Eiriksson, Lua

Randomized, Open-Label, Crossover Studies Evaluating the Effect of Food and Liquid Formulation on the Pharmacokinetics of the Novel Focal Adhesion Kinase (FAK) Inhibitor BI 853520

随机、开放标签、交叉研究,评估食物和液体制剂对新型黏着斑激酶 (FAK) 抑制剂 BI 853520 药代动力学的影响

Verheijen, Remy B; van der Biessen, Diane A J; Hotte, Sebastien J; Siu, Lillian L; Spreafico, Anna; de Jonge, Maja J A; Pronk, Linda C; De Vos, Filip Y F L; Schnell, David; Hirte, Hal W; Steeghs, Neeltje; Lolkema, Martijn P

Phase I Study of BI 853520, an Inhibitor of Focal Adhesion Kinase, in Patients with Advanced or Metastatic Nonhematologic Malignancies

BI 853520(一种局灶性黏附激酶抑制剂)治疗晚期或转移性非血液系统恶性肿瘤患者的I期研究

de Jonge, Maja J A; Steeghs, Neeltje; Lolkema, Martijn P; Hotte, Sebastien J; Hirte, Hal W; van der Biessen, Diane A J; Abdul Razak, Albiruni R; De Vos, Filip Y F L; Verheijen, Remy B; Schnell, David; Pronk, Linda C; Jansen, Monique; Siu, Lillian L

Association of Ipilimumab With Safety and Antitumor Activity in Women With Metastatic or Recurrent Human Papillomavirus-Related Cervical Carcinoma

伊匹木单抗与转移性或复发性人乳头瘤病毒相关宫颈癌女性患者的安全性和抗肿瘤活性之间的关联

Lheureux, Stephanie; Butler, Marcus O; Clarke, Blaise; Cristea, Mihaela C; Martin, Lainie P; Tonkin, Katia; Fleming, Gini F; Tinker, Anna V; Hirte, Hal W; Tsoref, Daliah; Mackay, Helen; Dhani, Neesha C; Ghatage, Prafull; Weberpals, Johanne; Welch, Stephen; Pham, Nhu-An; Motta, Vinicius; Sotov, Valentin; Wang, Lisa; Karakasis, Katherine; Udagani, Smitha; Kamel-Reid, Suzanne; Streicher, Howard Z; Shaw, Patricia; Oza, Amit M

Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model

卵巢癌患者体内扩增的 CD56superbrightCD16+ NK 细胞在患者来源的异种移植小鼠模型中对自体肿瘤具有细胞毒性

Sophie M Poznanski, Tina Nham, Marianne V Chew, Amanda J Lee, Joanne A Hammill, Isabella Y Fan, Martin Butcher, Jonathan L Bramson, Dean A Lee, Hal W Hirte, Ali A Ashkar

Profile of erlotinib and its potential in the treatment of advanced ovarian carcinoma

厄洛替尼的概况及其在晚期卵巢癌治疗中的潜力

Hirte, Hal W