日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Structural exposure of different microtubule binding domains determines the propagation and toxicity of pathogenic tau conformers in Alzheimer's disease.

不同微管结合域的结构暴露决定了阿尔茨海默病中致病性 tau 构象体的传播和毒性

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1012926
Hromadkova Lenka, Kim Chae, Haldiman Tracy, Siddiqi Mohammad Khursheed, Surewicz Krystyna, Urquhart Kiley, Sadruddin Dur-E-Nayab, Peng Lihua, Zhu Xiongwei, Surewicz Witold K, Cohen Mark L, Chance Mark R, de Silva Rohan, Kiselar Janna, Safar Jiri G
其它
发表日期：2025
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Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-generation real-time quaking-induced conversion assay

利用第二代实时震动诱导转化试验检测匹配的死后皮肤和脑脊液样本中的朊病毒

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-024-56789-6
Baranová, Soňa; Moško, Tibor; Brůžová, Magdalena; Haldiman, Tracy; Kim, Chae; Safar, Jiri G; Matěj, Radoslav; Holada, Karel
微生物学
神经科学
发表日期：2024
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Propagation of distinct tau strains in neuronal systems with physiological tau expression

在具有生理性tau蛋白表达的神经元系统中，不同tau蛋白毒株的传播

期刊:
影响因子:
doi:10.1101/2024.05.14.594246
Voskobiynyk, Yuliya; Li, Zhiyong; Cochran, J Nicholas; Davis, M Natalie; Carullo, Nancy V N; Creed, Rose B; Buckingham, Susan C; Hall, Alicia M; Wilson, Scott M; Roberson, Erik D; Hromadkova, Lenka; Urquhart, Kiley; Kim, Chae; Haldiman, Tracy; Safar, Jiri
神经科学
发表日期：2024
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Distinct populations of highly potent TAU seed conformers in rapidly progressing Alzheimer's disease

在快速进展的阿尔茨海默病中存在不同的、高活性TAU种子构象体群体

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.abg0253
Kim, Chae; Haldiman, Tracy; Kang, Sang-Gyun; Hromadkova, Lenka; Han, Zhuang Zhuang; Chen, Wei; Lissemore, Frances; Lerner, Alan; de Silva, Rohan; Cohen, Mark L; Westaway, David; Safar, Jiri G
阿尔茨海默症
TAU
发表日期：2022
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Correction to: Diverse, evolving conformer populations drive distinct phenotypes in frontotemporal lobar degeneration caused by the same MAPT‑P301L mutation

更正：由同一 MAPT-P301L 突变引起的额颞叶变性中，多样化的、不断演化的构象异构体群体驱动着不同的表型

期刊:Acta Neuropathologica
影响因子:9.3
doi:10.1007/s00401-021-02262-x
Daude, Nathalie; Kim, Chae; Kang, Sang-Gyun; Eskandari-Sedighi, Ghazaleh; Haldiman, Tracy; Yang, Jing; Fleck, Shelaine C; Gomez-Cardona, Erik; Han, Zhuang Zhuang; Borrego-Ecija, Sergi; Wohlgemuth, Serene; Julien, Olivier; Wille, Holger; Molina-Porcel, Laura; Gelpi, Ellen; Safar, Jiri G; Westaway, David
发表日期：2021
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Structurally distinct external solvent-exposed domains drive replication of major human prions

结构不同的外部溶剂暴露区域驱动着主要人类朊病毒的复制。

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1009642
Siddiqi, Mohammad Khursheed; Kim, Chae; Haldiman, Tracy; Kacirova, Miroslava; Wang, Benlian; Bohon, Jen; Chance, Mark R; Kiselar, Janna; Safar, Jiri G
微生物学
发表日期：2021
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Diverse, evolving conformer populations drive distinct phenotypes in frontotemporal lobar degeneration caused by the same MAPT-P301L mutation

由同一 MAPT-P301L 突变引起的额颞叶变性中，多样化且不断演化的构象异构体群体驱动着不同的表型。

期刊:Acta Neuropathologica
影响因子:9.3
doi:10.1007/s00401-020-02148-4
Daude, Nathalie; Kim, Chae; Kang, Sang-Gyun; Eskandari-Sedighi, Ghazaleh; Haldiman, Tracy; Yang, Jing; Fleck, Shelaine C; Gomez-Cardona, Erik; Han, Zhuang Zhuang; Borrego-Ecija, Sergi; Wohlgemuth, Serene; Julien, Olivier; Wille, Holger; Molina-Porcel, Laura; Gelpi, Ellen; Safar, Jiri G; Westaway, David
发表日期：2020
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Artificial strain of human prions created in vitro

体外培养的人类朊病毒人工毒株

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-018-04584-z
Kim, Chae; Xiao, Xiangzhu; Chen, Shugui; Haldiman, Tracy; Smirnovas, Vitautas; Kofskey, Diane; Warren, Miriam; Surewicz, Krystyna; Maurer, Nicholas R; Kong, Qingzhong; Surewicz, Witold; Safar, Jiri G
微生物学
发表日期：2018
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Rapidly progressive Alzheimer's disease features distinct structures of amyloid-β

快速进展型阿尔茨海默病具有独特的β-淀粉样蛋白结构。

期刊:Brain
影响因子:11.7
doi:10.1093/brain/awv006
Cohen, Mark L; Kim, Chae; Haldiman, Tracy; ElHag, Mohamed; Mehndiratta, Prachi; Pichet, Termsarasab; Lissemore, Frances; Shea, Michelle; Cohen, Yvonne; Chen, Wei; Blevins, Janis; Appleby, Brian S; Surewicz, Krystyna; Surewicz, Witold K; Sajatovic, Martha; Tatsuoka, Curtis; Zhang, Shulin; Mayo, Ping; Butkiewicz, Mariusz; Haines, Jonathan L; Lerner, Alan J; Safar, Jiri G
阿尔茨海默症
发表日期：2015
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Structural determinants of phenotypic diversity and replication rate of human prions

人类朊病毒表型多样性和复制速率的结构决定因素

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1004832
Safar, Jiri G; Xiao, Xiangzhu; Kabir, Mohammad E; Chen, Shugui; Kim, Chae; Haldiman, Tracy; Cohen, Yvonne; Chen, Wei; Cohen, Mark L; Surewicz, Witold K
微生物学
发表日期：2015
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