日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions

线粒体通透性转换孔的特性、结构和功能:争议、共识、最新进展和未来方向

Bernardi, Paolo; Gerle, Christoph; Halestrap, Andrew P; Jonas, Elizabeth A; Karch, Jason; Mnatsakanyan, Nelli; Pavlov, Evgeny; Sheu, Shey-Shing; Soukas, Alexander A

The roles of cytosolic and intramitochondrial Ca(2+) and the mitochondrial Ca(2+)-uniporter (MCU) in the stimulation of mammalian oxidative phosphorylation

胞质和线粒体内Ca(2+)以及线粒体Ca(2+)单向转运蛋白(MCU)在刺激哺乳动物氧化磷酸化中的作用

Rutter, Guy A; McCormack, James G; Halestrap, Andrew P; Denton, Richard M

The role of succinate and ROS in reperfusion injury - A critical appraisal

琥珀酸和活性氧在再灌注损伤中的作用——一项批判性评价

Andrienko, Tatyana N; Pasdois, Philippe; Pereira, Gonçalo C; Ovens, Matthew J; Halestrap, Andrew P

The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters

抗肿瘤药物洛尼达明是线粒体丙酮酸载体和质膜单羧酸转运体的强效抑制剂。

Nancolas, Bethany; Guo, Lili; Zhou, Rong; Nath, Kavindra; Nelson, David S; Leeper, Dennis B; Blair, Ian A; Glickson, Jerry D; Halestrap, Andrew P

Quantification of active mitochondrial permeability transition pores using GNX-4975 inhibitor titrations provides insights into molecular identity

利用GNX-4975抑制剂滴定法对活性线粒体通透性转换孔进行定量分析,有助于深入了解分子特性。

Richardson, Andrew P; Halestrap, Andrew P

Identification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity

鉴定出 MCT1 与 AR-C155858 的关键结合位点残基,揭示了其亚型选择性的分子基础。

Nancolas, Bethany; Sessions, Richard B; Halestrap, Andrew P

The 'mitoflash' probe cpYFP does not respond to superoxide

“mitoflash”探针cpYFP对超氧化物没有反应。

Schwarzländer, Markus; Wagner, Stephan; Ermakova, Yulia G; Belousov, Vsevolod V; Radi, Rafael; Beckman, Joseph S; Buettner, Garry R; Demaurex, Nicolas; Duchen, Michael R; Forman, Henry J; Fricker, Mark D; Gems, David; Halestrap, Andrew P; Halliwell, Barry; Jakob, Ursula; Johnston, Iain G; Jones, Nick S; Logan, David C; Morgan, Bruce; Müller, Florian L; Nicholls, David G; Remington, S James; Schumacker, Paul T; Winterbourn, Christine C; Sweetlove, Lee J; Meyer, Andreas J; Dick, Tobias P; Murphy, Michael P

Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion

临床上,异丙肾上腺素和腺苷的连续治疗能够保护衰竭的心脏免受缺血和再灌注损伤。

Khaliulin, Igor; Halestrap, Andrew P; Bryant, Simon M; Dudley, Declan J; James, Andrew F; Suleiman, M-Saadeh

The C Ring of the F1Fo ATP Synthase Forms the Mitochondrial Permeability Transition Pore: A Critical Appraisal

F1Fo ATP合酶的C环形成线粒体通透性转换孔:一项批判性评价

Halestrap, Andrew P

Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury

喂食非致肥胖高脂饮食的小鼠心脏,其氧化状态、钙离子和线粒体均发生改变,同时对再灌注损伤的敏感性也增加。

Littlejohns, Ben; Pasdois, Philippe; Duggan, Simon; Bond, Andrew R; Heesom, Kate; Jackson, Christopher L; Angelini, Gianni D; Halestrap, Andrew P; Suleiman, M-Saadeh