Haljasorg相关文献与解析，生知库 | 链接生命科学的每一步

Peptide-Drug Conjugate for Therapeutic Reprogramming of Tumor-Associated Macrophages in Breast Cancer.

用于乳腺癌肿瘤相关巨噬细胞治疗性重编程的肽-药物偶联物

doi:10.1002/advs.202410288

Lepland Anni, Peranzoni Elisa, Haljasorg Uku, Asciutto Eliana K, CrespÃ-Amer Maria, Modesti Lorenzo, Kilk Kalle, Lombardia Manuel, Acosta Gerardo, Royo Miriam, Peterson PÃ¤rt, Marigo Ilaria, Teesalu Tambet, Scodeller Pablo

The Development of Cell-Penetrating Peptides for Efficient and Selective In Vivo Expression of mRNA in Spleen Tissue

开发细胞穿透肽以实现脾脏组织中mRNA的高效选择性体内表达

期刊:Pharmaceutics

影响因子:5.5

doi:10.3390/pharmaceutics15030952

Porosk, Ly; Härk, Heleri Heike; Arukuusk, Piret; Haljasorg, Uku; Peterson, Pärt; Kurrikoff, Kaido

细胞生物学

发表日期：2023

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Conjugates of adenosine mimetics and arginine-rich peptides serve as inhibitors and fluorescent probes but not as long-lifetime photoluminescent probes for protein arginine methyltransferases

腺苷模拟物和富含精氨酸的肽的结合物可用作抑制剂和荧光探针，但不能用作蛋白质精氨酸甲基转移酶的长寿命光致发光探针

期刊:Journal of Peptide Science

影响因子:1.8

doi:10.1002/psc.3456

Darja Lavogina, Naila Nasirova, Tanel Sõrmus, Taavo Tähtjärv, Erki Enkvist, Kaido Viht, Tõiv Haljasorg, Koit Herodes, Jana Jaal, Asko Uri

信号转导

发表日期：2023

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Protective antibodies and T cell responses to Omicron variant after the booster dose of BNT162b2 vaccine

接种BNT162b2疫苗加强剂后，针对Omicron变异株的保护性抗体和T细胞反应

期刊:Cell Reports Medicine

影响因子:11.7

doi:10.1016/j.xcrm.2022.100716

Paul Naaber ，Liina Tserel ，Kadri Kangro ，Marite Punapart ，Epp Sepp ，Virge Jürjenson ，Jaanika Kärner ，Liis Haljasmägi ，Uku Haljasorg ，Marilin Kuusk ，Eve Sankovski ，Anu Planken ，Mart Ustav ，Eva Žusinaite ，Joachim M Gerhold ，Kai Kisand ，Pärt Peterson

Depletion of Mannose Receptor-Positive Tumor-associated Macrophages via a Peptide-targeted Star-shaped Polyglutamate Inhibits Breast Cancer Progression in Mice

通过靶向星形聚谷氨酸肽耗竭甘露糖受体阳性肿瘤相关巨噬细胞可抑制小鼠乳腺癌进展

期刊:Cancer Research Communications

影响因子:2

doi:10.1158/2767-9764.CRC-22-0043

Anni Lepland ，Alessio Malfanti ，Uku Haljasorg ，Eliana K Asciutto ，Monica Pickholz ，Mauro Bringas ，Snežana Đorđević ，Liis Salumäe ，Pärt Peterson ，Tambet Teesalu ，María J Vicent ，Pablo Scodeller

Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation

对小鼠模型中显性AIRE突变的机制解析揭示了AIRE的自身调节

期刊:Journal of Experimental Medicine

影响因子:12.6

doi:10.1084/jem.20201076

Yael Goldfarb ，Tal Givony ，Noam Kadouri ，Jan Dobeš ，Cristina Peligero-Cruz ，Itay Zalayat ，Golda Damari ，Bareket Dassa ，Shifra Ben-Dor ，Yael Gruper ，Bergithe E Oftedal ，Eirik Bratland ，Martina M Erichsen ，Amund Berger ，Ayelet Avin ，Shir Nevo ，Uku Haljasorg ，Yael Kuperman ，Adi Ulman ，Rebecca Haffner-Krausz ，Ziv Porat ，Ulus Atasoy ，Dena Leshkowitz ，Eystein S Husebye # ，Jakub Abramson #

AIRE

发表日期：2021

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miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis

miR-146b可能辅助miRNA-146a抑制银屑病中的角质形成细胞增殖和炎症反应

期刊:Journal of Investigative Dermatology

影响因子:5.7

doi:10.1016/j.jid.2017.05.012

Hermann, Helen; Runnel, Toomas; Aab, Alar; Baurecht, Hansjörg; Rodriguez, Elke; Magilnick, Nathaniel; Urgard, Egon; Šahmatova, Liisi; Prans, Ele; Maslovskaja, Julia; Abram, Kristi; Karelson, Maire; Kaldvee, Bret; Reemann, Paula; Haljasorg, Uku; Rückert, Beate; Wawrzyniak, Paulina; Weichenthal, Michael; Mrowietz, Ulrich; Franke, Andre; Gieger, Christian; Barker, Jonathan; Trembath, Richard; Tsoi, Lam C; Elder, James T; Tkaczyk, Eric R; Kisand, Kai; Peterson, Pärt; Kingo, Külli; Boldin, Mark; Weidinger, Stephan; Akdis, Cezmi A; Rebane, Ana

DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes

DNA断裂和染色质结构变化增强自身免疫调节靶基因的转录

期刊:Journal of Biological Chemistry

影响因子:4

doi:10.1074/jbc.M116.764704

Mithu Guha, Mario Saare, Julia Maslovskaja, Kai Kisand, Ingrid Liiv, Uku Haljasorg, Tõnis Tasa, Andres Metspalu, Lili Milani, Pärt Peterson

A Selective Biligand Inhibitor of CK2 Increases Caspase-3 Activity in Cancer Cells and Inhibits Platelet Aggregation

CK2 的选择性双配体抑制剂可增加癌细胞中的 Caspase-3 活性并抑制血小板聚集

期刊:ChemMedChem

影响因子:3.6

doi:10.1002/cmdc.201700457

Hedi Rahnel, Kaido Viht, Darja Lavogina, Olga Mazina, Tõiv Haljasorg, Erki Enkvist, Asko Uri

Laser Ablation APCI-HRMS Method for the Analysis of Cultural Heritage Materials

激光烧蚀APCI-HRMS法分析文化遗产材料

Peptide-Drug Conjugate for Therapeutic Reprogramming of Tumor-Associated Macrophages in Breast Cancer.

用于乳腺癌肿瘤相关巨噬细胞治疗性重编程的肽-药物偶联物

The Development of Cell-Penetrating Peptides for Efficient and Selective In Vivo Expression of mRNA in Spleen Tissue

开发细胞穿透肽以实现脾脏组织中mRNA的高效选择性体内表达

Conjugates of adenosine mimetics and arginine-rich peptides serve as inhibitors and fluorescent probes but not as long-lifetime photoluminescent probes for protein arginine methyltransferases

腺苷模拟物和富含精氨酸的肽的结合物可用作抑制剂和荧光探针，但不能用作蛋白质精氨酸甲基转移酶的长寿命光致发光探针

Protective antibodies and T cell responses to Omicron variant after the booster dose of BNT162b2 vaccine

接种BNT162b2疫苗加强剂后，针对Omicron变异株的保护性抗体和T细胞反应

Depletion of Mannose Receptor-Positive Tumor-associated Macrophages via a Peptide-targeted Star-shaped Polyglutamate Inhibits Breast Cancer Progression in Mice

通过靶向星形聚谷氨酸肽耗竭甘露糖受体阳性肿瘤相关巨噬细胞可抑制小鼠乳腺癌进展

Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation

对小鼠模型中显性AIRE突变的机制解析揭示了AIRE的自身调节

miR-146b Probably Assists miRNA-146a in the Suppression of Keratinocyte Proliferation and Inflammatory Responses in Psoriasis

miR-146b可能辅助miRNA-146a抑制银屑病中的角质形成细胞增殖和炎症反应

DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes

DNA断裂和染色质结构变化增强自身免疫调节靶基因的转录

A Selective Biligand Inhibitor of CK2 Increases Caspase-3 Activity in Cancer Cells and Inhibits Platelet Aggregation

CK2 的选择性双配体抑制剂可增加癌细胞中的 Caspase-3 活性并抑制血小板聚集