Halls Michelle L相关文献与解析，生知库 | 链接生命科学的每一步

Bayly-Jones Charles, Lupton Christopher J, D'Andrea Laura, Chang Yong-Gang, Jones Gareth D, Steele Joel R, Venugopal Hari, Schittenhelm Ralf B, Halls Michelle L, Ellisdon Andrew M

其它

Human

发表日期：2024

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Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations

预组装的GPCR信号复合物介导细胞对超低配体浓度的不同反应

期刊:Science Signaling

影响因子:6.6

doi:10.1126/scisignal.aan1188

Civciristov, Srgjan; Ellisdon, Andrew M; Suderman, Ryan; Pon, Cindy K; Evans, Bronwyn A; Kleifeld, Oded; Charlton, Steven J; Hlavacek, William S; Canals, Meritxell; Halls, Michelle L

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

神经激肽1受体在内体中的信号传导介导持续性伤害感受，是延长疼痛缓解的有效治疗靶点。

期刊:Science Translational Medicine

影响因子:14.6

doi:10.1126/scitranslmed.aal3447

Jensen, Dane D; Lieu, TinaMarie; Halls, Michelle L; Veldhuis, Nicholas A; Imlach, Wendy L; Mai, Quynh N; Poole, Daniel P; Quach, Tim; Aurelio, Luigi; Conner, Joshua; Herenbrink, Carmen Klein; Barlow, Nicholas; Simpson, Jamie S; Scanlon, Martin J; Graham, Bimbil; McCluskey, Adam; Robinson, Phillip J; Escriou, Virginie; Nassini, Romina; Materazzi, Serena; Geppetti, Pierangelo; Hicks, Gareth A; Christie, Macdonald J; Porter, Christopher J H; Canals, Meritxell; Bunnett, Nigel W

信号转导

发表日期：2017

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Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

降钙素基因相关肽受体的内体信号传导介导疼痛传递

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1706656114

Yarwood, Rebecca E; Imlach, Wendy L; Lieu, TinaMarie; Veldhuis, Nicholas A; Jensen, Dane D; Klein Herenbrink, Carmen; Aurelio, Luigi; Cai, Zhijian; Christie, MacDonald J; Poole, Daniel P; Porter, Christopher J H; McLean, Peter; Hicks, Gareth A; Geppetti, Pierangelo; Halls, Michelle L; Canals, Meritxell; Bunnett, Nigel W

信号转导

发表日期：2017

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β2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer

肿瘤细胞上的β2-肾上腺素受体在乳腺癌小鼠模型中应激增强的转移过程中起着关键作用

期刊:Brain Behavior and Immunity

影响因子:7.6

doi:10.1016/j.bbi.2016.06.011

Chang, Aeson; Le, Caroline P; Walker, Adam K; Creed, Sarah J; Pon, Cindy K; Albold, Sabine; Carroll, Dominic; Halls, Michelle L; Lane, J Robert; Riedel, Bernhard; Ferrari, Davide; Sloan, Erica K

International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides

国际基础与临床药理学联合会。第95届年会。松弛素家族肽受体1-4（松弛素家族肽的受体）的药理学和生物学作用的最新进展。

期刊:Pharmacological Reviews

影响因子:17.3

doi:10.1124/pr.114.009472

Halls, Michelle L; Bathgate, Ross A D; Sutton, Steve W; Dschietzig, Thomas B; Summers, Roger J

信号转导

发表日期：2015

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Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas GÎ²Î³ subunits exert opposing effects depending on the G-protein source.

毒蕈碱受体通过新的磷酸化位点刺激 AC2，而 Gββ 亚基则根据 G 蛋白的来源发挥相反的作用

期刊:Biochemical Journal

影响因子:4.3

doi:10.1042/BJ20120279

Shen Jia X, Wachten Sebastian, Halls Michelle L, Everett Katy L, Cooper Dermot M F

A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex

AC8 中的一个关键磷酸化位点通过 AC8-AKAP79-PKA 信号复合物介导 Ca(2+) 依赖性 cAMP 动态的调控。

期刊:Journal of Cell Science

影响因子:3.6

doi:10.1242/jcs.111427

Willoughby, Debbie; Halls, Michelle L; Everett, Katy L; Ciruela, Antonio; Skroblin, Philipp; Klussmann, Enno; Cooper, Dermot M F

Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu.

腺苷酸环化酶 AC8 通过在富含胆固醇的环境中募集肌动蛋白细胞骨架来直接控制其微环境

期刊:Journal of Cell Science

影响因子:3.6

doi:10.1242/jcs.091090

Ayling Laura J, Briddon Stephen J, Halls Michelle L, Hammond Gerald R V, Vaca Luis, Pacheco Jonathan, Hill Stephen J, Cooper Dermot M F

细胞生物学

发表日期：2012

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Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex

预组装的 RXFP1、AKAP79、AC2、β-arrestin 2、PDE4D3 复合物介导亚皮摩尔级松弛素信号传导。

期刊:EMBO Journal

影响因子:8.3

doi:10.1038/emboj.2010.168

Halls, Michelle L; Cooper, Dermot M F

信号转导

发表日期：2010

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Structure of the human TSC:WIPI3 lysosomal recruitment complex.

人类 TSC:WIPI3 溶酶体募集复合物的结构

Preassembled GPCR signaling complexes mediate distinct cellular responses to ultralow ligand concentrations

预组装的GPCR信号复合物介导细胞对超低配体浓度的不同反应

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

神经激肽1受体在内体中的信号传导介导持续性伤害感受，是延长疼痛缓解的有效治疗靶点。

Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

降钙素基因相关肽受体的内体信号传导介导疼痛传递

β2-Adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer

肿瘤细胞上的β2-肾上腺素受体在乳腺癌小鼠模型中应激增强的转移过程中起着关键作用

International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides

国际基础与临床药理学联合会。第95届年会。松弛素家族肽受体1-4（松弛素家族肽的受体）的药理学和生物学作用的最新进展。

Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas GÎ²Î³ subunits exert opposing effects depending on the G-protein source.

毒蕈碱受体通过新的磷酸化位点刺激 AC2，而 Gββ 亚基则根据 G 蛋白的来源发挥相反的作用

A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex

AC8 中的一个关键磷酸化位点通过 AC8-AKAP79-PKA 信号复合物介导 Ca(2+) 依赖性 cAMP 动态的调控。

Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu.

腺苷酸环化酶 AC8 通过在富含胆固醇的环境中募集肌动蛋白细胞骨架来直接控制其微环境

Sub-picomolar relaxin signalling by a pre-assembled RXFP1, AKAP79, AC2, beta-arrestin 2, PDE4D3 complex

预组装的 RXFP1、AKAP79、AC2、β-arrestin 2、PDE4D3 复合物介导亚皮摩尔级松弛素信号传导。