日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Four Decades of Cytochrome P450 2B Research: From Protein Adducts to Protein Structures and Beyond

细胞色素P450 2B研究四十年:从蛋白质加合物到蛋白质结构及其他

Roberts, Arthur G; Stevens, Jeffrey C; Szklarz, Grazyna D; Scott, Emily E; Kumar, Santosh; Shah, Manish B; Halpert, James R

So many roads traveled: A career in science and administration

走过的路太多了:科学与行政管理方面的职业生涯

Halpert, James R

Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog

CYP2B6 与依非韦伦类似物复合物的晶体结构

Shah, Manish B; Zhang, Qinghai; Halpert, James R

Halogen-π Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity

细胞色素P450活性位点中的卤素-π相互作用:对人类CYP2B6底物选择性的结构解析

Shah, Manish B; Liu, Jingbao; Zhang, Qinghai; Stout, C David; Halpert, James R

Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations

香豆素衍生物作为哺乳动物细胞色素P450 2B4和2B6的底物探针:评估7-烷氧基链长、卤素取代和非活性位点突变的重要性

Liu, Jingbao; Shah, Manish B; Zhang, Qinghai; Stout, C David; Halpert, James R; Wilderman, P Ross

Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry

利用X射线晶体衍射和氘交换质谱分析去垢剂结合对细胞色素P450 2B4结构的影响

Shah, Manish B; Jang, Hyun-Hee; Wilderman, P Ross; Lee, David; Li, Sheng; Zhang, Qinghai; Stout, C David; Halpert, James R

Interactions among cytochromes P450 in microsomal membranes: oligomerization of cytochromes P450 3A4, 3A5, and 2E1 and its functional consequences

微粒体膜中细胞色素P450之间的相互作用:细胞色素P450 3A4、3A5和2E1的寡聚化及其功能后果

Davydov, Dmitri R; Davydova, Nadezhda Y; Sineva, Elena V; Halpert, James R

Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida

对沙漠林鼠(Neotoma lepida)细胞色素P450 2B的功能表征

Wilderman, P Ross; Jang, Hyun-Hee; Malenke, Jael R; Salib, Mariam; Angermeier, Elisabeth; Lamime, Sonia; Dearing, M Denise; Halpert, James R

Pivotal role of P450-P450 interactions in CYP3A4 allostery: the case of α-naphthoflavone

P450-P450相互作用在CYP3A4变构中的关键作用:以α-萘黄酮为例

Davydov, Dmitri R; Davydova, Nadezhda Y; Sineva, Elena V; Kufareva, Irina; Halpert, James R

CYP261 enzymes from deep sea bacteria: a clue to conformational heterogeneity in cytochromes P450

来自深海细菌的CYP261酶:揭示细胞色素P450构象异质性的线索

Davydov, Dmitri R; Sineva, Elena V; Davydova, Nadezhda Y; Bartlett, Douglas H; Halpert, James R