Spatial dissection of tumour microenvironments in gastric cancers reveals the immunosuppressive crosstalk between CCL2+ fibroblasts and STAT3-activated macrophages
对胃癌肿瘤微环境的空间解剖揭示了CCL2+成纤维细胞和STAT3激活的巨噬细胞之间的免疫抑制性相互作用
期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2024-332901
Lee, Sung Hak; Lee, Dagyeong; Choi, Junyong; Oh, Hye Jeong; Ham, In-Hye; Ryu, Daeun; Lee, Seo-Yeong; Han, Dong-Jin; Kim, Sunmin; Moon, Youngbeen; Song, In-Hye; Song, Kyo Young; Lee, Hyeseong; Lee, Seungho; Hur, Hoon; Kim, Tae-Min
胃癌
巨噬细胞
成纤维细胞
肿瘤
肿瘤免疫
JAK/STAT
CCL2
巨噬细胞
STAT3
细胞生物学
肿瘤微环境
免疫/内分泌