日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural basis for collagen recognition by the Streptococcus pyogenes M3 protein and its involvement in biofilm

化脓性链球菌M3蛋白识别胶原蛋白的结构基础及其在生物膜形成中的作用

Wojnowska, Marta; Wajima, Takeaki; Yelland, Tamas; Ludewig, Hannes; Hagan, Robert M; McCurry, Olivia F; Watt, Grant; Hamaia, Samir W; Bihan, Dominique; Malcor, Jean-Daniel; Bonna, Arkadiusz; Bergsten, Helena; Palma Medina, Laura Marcela; Svensson, Mattias; Oppegaard, Oddvar; Skrede, Steinar; Arnell, Per; Hyldegaard, Ole; Farndale, Richard W; Norrby-Teglund, Anna; Schwarz-Linek, Ulrich

Isoform-specific N-linked glycosylation of NaV channel α-subunits alters β-subunit binding sites

NaV通道α亚基的亚型特异性N-连接糖基化会改变β亚基的结合位点。

Beaudoin, Christopher A; Kohli, Manas; Salvage, Samantha C; Liu, Hengrui; Arundel, Samuel J; Hamaia, Samir W; Lei, Ming; Huang, Christopher L-H; Jackson, Antony P

In silico analysis of mutations near S1/S2 cleavage site in SARS-CoV-2 spike protein reveals increased propensity of glycosylation in Omicron strain

对SARS-CoV-2刺突蛋白S1/S2切割位点附近突变的计算机模拟分析表明,Omicron毒株的糖基化倾向增加。

Beaudoin, Christopher A; Pandurangan, Arun P; Kim, So Yeon; Hamaia, Samir W; Huang, Christopher L-H; Blundell, Tom L; Vedithi, Sundeep Chaitanya; Jackson, Antony P

Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion

Multimerin 1 在体内支持血小板功能,并与纤维状胶原蛋白中的特定 GPAGPOGPX 基序结合,从而增强血小板黏附。

Leatherdale, Alexander; Parker, D'Andra; Tasneem, Subia; Wang, Yiming; Bihan, Dominique; Bonna, Arkadiusz; Hamaia, Samir W; Gross, Peter L; Ni, Heyu; Doble, Bradley W; Lillicrap, David; Farndale, Richard W; Hayward, Catherine P M

Can the SARS-CoV-2 Spike Protein Bind Integrins Independent of the RGD Sequence?

SARS-CoV-2 刺突蛋白能否在不依赖 RGD 序列的情况下结合整合素?

Beaudoin, Christopher A; Hamaia, Samir W; Huang, Christopher L-H; Blundell, Tom L; Jackson, Antony P

The synthesis and coupling of photoreactive collagen-based peptides to restore integrin reactivity to an inert substrate, chemically-crosslinked collagen.

合成和偶联光反应性胶原蛋白基肽,以恢复整合素对惰性底物(化学交联胶原蛋白)的反应性

Malcor Jean-Daniel, Bax Daniel, Hamaia Samir W, Davidenko Natalia, Best Serena M, Cameron Ruth E, Farndale Richard W, Bihan Dominique

Intrinsic local destabilization of the C-terminus predisposes integrin α1 I domain to a conformational switch induced by collagen binding

C端固有的局部不稳定使整合素α1 I结构域易于发生由胶原蛋白结合诱导的构象转变。

Nunes, Ana Monica; Zhu, Jie; Jezioro, Jacqueline; Minetti, Conceição A S A; Remeta, David P; Farndale, Richard W; Hamaia, Samir W; Baum, Jean

Optimisation of UV irradiation as a binding site conserving method for crosslinking collagen-based scaffolds

优化紫外线照射作为一种保留结合位点的胶原基支架交联方法

Davidenko, Natalia; Bax, Daniel V; Schuster, Carlos F; Farndale, Richard W; Hamaia, Samir W; Best, Serena M; Cameron, Ruth E

The recognition of collagen and triple-helical toolkit peptides by MMP-13: sequence specificity for binding and cleavage

MMP-13对胶原蛋白和三螺旋工具包肽的识别:结合和切割的序列特异性

Howes, Joanna-Marie; Bihan, Dominique; Slatter, David A; Hamaia, Samir W; Packman, Len C; Knauper, Vera; Visse, Robert; Farndale, Richard W