日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Multiple tissue-specific epigenetic alterations regulate persistent gene expression changes following developmental DES exposure in mouse reproductive tissues

小鼠生殖组织中,发育期暴露于己烯雌酚后,多种组织特异性表观遗传改变调控着持续存在的基因表达变化。

Jefferson, Tanner B; Wang, Tianyuan; Jefferson, Wendy N; Li, Yin; Hamilton, Katherine J; Wade, Paul A; Williams, Carmen J; Korach, Kenneth S

A Novel Mouse Model to Analyze Non-Genomic ERα Physiological Actions

一种用于分析非基因组ERα生理作用的新型小鼠模型

Arao, Yukitomo; Gruzdev, Artiom; Scott, Gregory J; Ray, Manas K; Donoghue, Lauren J; Neufeld, Thomas I; Lierz, Sydney L; Stefkovich, Megan L; Mathura, Emilie; Jefferson, Tanner; Foley, Julie F; Mahler, Beth W; Asghari, Arvand; Le, Courtney; McConnell, Bradley K; Stephen, Robert; Berridge, Brian R; Hamilton, Katherine J; Hewitt, Sylvia C; Umetani, Michihisa; Korach, Kenneth S

The genomic regulatory elements for estrogen receptor alpha transactivation-function-1 regulated genes

雌激素受体α转录激活功能1调控基因的基因组调控元件

Arao, Yukitomo; Hamilton, Katherine J; Grimm, Sara A; Korach, Kenneth S

DNA methylation and transcriptome aberrations mediated by ERα in mouse seminal vesicles following developmental DES exposure

发育期暴露于己烯雌酚 (DES) 后,小鼠精囊中雌激素受体α (ERα) 介导的DNA甲基化和转录组异常

Li, Yin; Hamilton, Katherine J; Wang, Tianyuan; Coons, Laurel A; Jefferson, Wendy N; Li, Ruifang; Wang, Yu; Grimm, Sara A; Ramsey, J Tyler; Liu, Liwen; Gerrish, Kevin E; Williams, Carmen J; Wade, Paul A; Korach, Kenneth S

N-terminal transactivation function, AF-1, of estrogen receptor alpha controls obesity through enhancement of energy expenditure

雌激素受体α的N端转录激活功能AF-1通过增强能量消耗来控制肥胖。

Arao, Yukitomo; Hamilton, Katherine J; Lierz, Sydney L; Korach, Kenneth S

Experimental models for evaluating non-genomic estrogen signaling

用于评估非基因组雌激素信号的实验模型

Stefkovich, Megan L; Arao, Yukitomo; Hamilton, Katherine J; Korach, Kenneth S

Estrogen Hormone Biology

雌激素生物学

Hamilton, Katherine J; Hewitt, Sylvia C; Arao, Yukitomo; Korach, Kenneth S

Diethylstilbestrol (DES)-stimulated hormonal toxicity is mediated by ERα alteration of target gene methylation patterns and epigenetic modifiers (DNMT3A, MBD2, and HDAC2) in the mouse seminal vesicle

己烯雌酚(DES)刺激的激素毒性是通过雌激素受体α(ERα)改变小鼠精囊中靶基因的甲基化模式和表观遗传修饰因子(DNMT3A、MBD2和HDAC2)介导的。

Li, Yin; Hamilton, Katherine J; Lai, Anne Y; Burns, Katherine A; Li, Leping; Wade, Paul A; Korach, Kenneth S

A single gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts the adult uterine response to estradiol in mice.

小鼠妊娠期单次接触 2,3,7,8-四氯二苯并-对-二恶英会破坏成年子宫对雌二醇的反应

Burns Katherine A, Zorrilla Leah M, Hamilton Katherine J, Reed Casey E, Birnbaum Linda S, Korach Kenneth S

Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators

雌激素受体α AF-2突变导致拮抗剂作用逆转,并揭示雌激素受体调节剂的组织选择性功能。

Arao, Yukitomo; Hamilton, Katherine J; Ray, Manas K; Scott, Gregory; Mishina, Yuji; Korach, Kenneth S