日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Subcellular Cartography of the Phosphoinositide Multiverse

磷脂酰肌醇多元宇宙的亚细胞图谱

Ricci, Morgan M C; Weckerly, Claire C; Hammond, Gerald R V

In Cellulo pharmacological profiling and genomic editing reveals paralog-specific targets for PA generation during PLC signaling.

在 Cellulo 中,药理学分析和基因组编辑揭示了 PLC 信号传导过程中 PA 生成的旁系同源特异性靶点。

Weckerly Claire C, Murtagh Olivia L, Swayhoover Tiernan, Pemberton Joshua G, Hsu Ku-Lung, Hammond Gerald R V

MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids.

MTMR通过控制质膜磷脂水平来调节KRAS功能

Lange Taylor E, Naji Ali, van der Hoeven Ransome, Liang Hong, Zhou Yong, Hammond Gerald R V, Hancock John F, Cho Kwang-Jin

Single-molecule lipid biosensors mitigate inhibition of endogenous effector proteins.

单分子脂质生物传感器可减轻内源性效应蛋白的抑制作用

Holmes Victoria L, Ricci Morgan M C, Weckerly Claire C, Worcester Michael, Hammond Gerald R V

Quantitative comparison of PI(3,5)P(2) biosensors reveals SnxA is the most sensitive and unbiased

对PI(3,5)P(2)生物传感器的定量比较表明,SnxA是最灵敏且无偏的。

Swayhoover, Tiernan; Weckerly, Claire C; Hammond, Gerald R V

Stereoselective Degradation of Diacylglycerol Kinases Potentiate T cell Activation and Tumor Cell Cytotoxicity

二酰甘油激酶的立体选择性降解可增强T细胞活化和肿瘤细胞毒性

Shaikh, Minhaj; Mookherjee, Surya Pravo; Weckerly, Claire C; Libby, Adam H; Xiao, Aizhen; Zhao, Yunge; Vaidya, Sagar D; Kim, AeRyon; Li, Zhihong; Ware, Madeleine L; Marants, Michelle; Murtagh, Olivia L; Wolfe, Wesley J; Bullock, Timothy Nj; Purow, Benjamin W; Hammond, Gerald R V; Hsu, Ku-Lung

PIP4K attenuates PIP5K lipid kinase activity by disrupting membrane-mediated dimerization.

PIP4K 通过破坏膜介导的二聚化作用来减弱 PIP5K 脂质激酶活性。

Duewell Benjamin R, Chirumbolo Michael J, Fernandez-Ortiz Samantha M, Hammond Gerald R V, Hansen Scott D

Beyond PI3Ks: targeting phosphoinositide kinases in disease

超越PI3K:靶向疾病中的磷脂酰肌醇激酶

Burke, John E; Triscott, Joanna; Emerling, Brooke M; Hammond, Gerald R V

Molding a PI(3,5)P2 biosensor

PI(3,5)P2生物传感器的成型

Weckerly, Claire C; Hammond, Gerald R V

PI(4,5)P2: signaling the plasma membrane

PI(4,5)P2:传递质膜信号

Wills, Rachel C; Hammond, Gerald R V