日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Phase I study of BMS-986299, an NLRP3 agonist, as monotherapy and in combination with nivolumab and ipilimumab in patients with advanced solid tumors

BMS-986299（一种 NLRP3 激动剂）单药治疗以及与纳武利尤单抗和伊匹木单抗联合治疗晚期实体瘤患者的 I 期研究

期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-010013
Nelson, Blessie E; O'Brien, Shaun; Sheth, Rahul A; Hong, David S; Naing, Aung; Zhang, Xiaoping; Xu, Amy; Hamuro, Lora; Suryawanshi, Rasika; McKinley, Derrick; Novosiadly, Ruslan D; Piha-Paul, Sarina A
NLRP3
LRP3
多发性硬化症
发表日期：2025
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IQ Survey Results on Current Industry Practices: Part 2-Quantitative Evaluations of Immunogenicity Assessment

IQ调查结果：当前行业实践——第二部分：免疫原性评估的定量评价

期刊:Clinical Pharmacology & Therapeutics
影响因子:5.5
doi:10.1002/cpt.3573
Richards, Susan; Winzenborg, Insa; Luedtke, Doreen; Niu, Tao; Hamuro, Lora; Kowalski, Karey; Leu, Jocelyn H; Yang, Jianning; Ganti, Vaishnavi; Bhattacharya, Indranil; Gueorguieva, Ivelina; Mostafa, Nael; Grimaldi, Christine; Wu, Benjamin
免疫/内分泌
发表日期：2025
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Administration of nivolumab plus ipilimumab: Infusion of the fixed-ratio combination versus sequential infusions in two randomized controlled trials of metastatic melanoma (CheckMate 742) and renal cell carcinoma (CheckMate 800)

纳武利尤单抗联合伊匹木单抗的给药：在两项转移性黑色素瘤（CheckMate 742）和肾细胞癌（CheckMate 800）的随机对照试验中，比较固定比例组合输注与序贯输注的效果

期刊:Cancer
影响因子:5.1
doi:10.1002/cncr.35962
Menzies, Alexander M; Salman, Pamela; Frontera, Osvaldo Arén; Pook, David; Hocking, Christopher M; Zakharia, Yousef; Gurney, Howard; Gedye, Craig; Goh, Jeffrey C; Telivala, Bijoy; Grob, Jean-Jacques; Lebbé, Céleste; de la Cruz Merino, Luis; Machet, Laurent; Neidhardt, Eve-Marie; Qureshi, Anila; Hosein, Fareeda; Hamuro, Lora; Simsek, Burcin; Amin, Asim
黑色素瘤
肿瘤
肿瘤免疫
肾癌
细胞生物学
发表日期：2025
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JNJ-78306358, a first-in-class bispecific T cell engaging antibody targeting CD3 and HLA-G

JNJ-78306358 是一种首创的双特异性 T 细胞接合抗体，靶向 CD3 和 HLA-G。

期刊:iScience
影响因子:4.6
doi:10.1016/j.isci.2025.111876
Nataša Obermajer ，Adam Zwolak ，Kelly van de Ven ，Shana Versmissen ，Krista Menard ，Katharine Rogers ，Ted Petley ，Dan Weinstock ，Jason Aligo ，Jaymala Patel ，Ken Tian ，Lorraine Angelillo ，Fang Yi ，Stephen Jarantow ，Keith Schutsky ，Yoshitomo Hamuro ，Diana Alvarez Arias ，Kristel Buyens ，Tsun-Wen Sheena Yao ，Vince Torti ，Aleksandra Brajic ，Brian Geist ，Marjolein van Heerden ，Gerald Chu ，Bie Verbist ，Maté Ongenaert ，Julien Häsler ，Kathryn Packman ，Jacintha Shenton ，Laurie Lenox ，Jacalyn Clawson ，Regina J Brown ，Josh Lauring ，James G Greger ，Dirk Brehmer ，Sanjaya Singh ，Matthew V Lorenzi ，Sylvie Laquerre
CD3
细胞生物学
T细胞
发表日期：2025
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A Novel Empirical Autoinduction Model to Characterize the Population Pharmacokinetics and Recommend Dose for Repotrectinib in Adult and Adolescents With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

一种新型经验性自诱导模型，用于表征携带ALK、ROS1或NTRK1-3重排的晚期实体瘤成人和青少年患者的瑞波替尼群体药代动力学并推荐剂量

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.70036
Du, Shengnan; Hu, Zheyi; Shen, Jun; Hamuro, Lora; Lam, Justine; Lu, Ming; Zhu, Li; Roy, Amit; Kondic, Anna
ALK
NTRK1
发表日期：2025
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Exposure-Response Analysis of Repotrectinib to Support the Dose Recommendation for Patients With ROS1-Positive NSCLC or NTRK-Positive Solid Tumors

对瑞波替尼进行暴露-反应分析，以支持ROS1阳性非小细胞肺癌或NTRK阳性实体瘤患者的剂量推荐

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.70102
Du, Shengnan; Hu, Zheyi; Shen, Jun; Zhu, Li; Roy, Amit; Lam, Justine; Lu, Ming; Kondic, Anna; Hamuro, Lora
肺癌
细胞生物学
肿瘤
肿瘤免疫
发表日期：2025
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Pharmacokinetic and Exposure-Response Modeling Support Body Surface Area-Based Dosing of Farletuzumab Ecteribulin in Japanese Patients with Solid Tumors

药代动力学和暴露-反应模型支持基于体表面积的法妥珠单抗依克立布林给药方案用于日本实体瘤患者

期刊:Journal of Clinical Pharmacology
影响因子:2.3
doi:10.1002/jcph.6187
Hayato, Seiichi; Hamuro, Lora; Shimizu, Toshio; Yonemori, Kan; Nishio, Shin; Yunokawa, Mayu; Yoshida, Tatsuya; Nishio, Makoto; Matsumoto, Koji; Takehara, Kazuhiro; Hasegawa, Kosei; Kozuki, Toshiyuki; Hirashima, Yasuyuki; Kato, Hidenori; Miura, Takuma; Nomoto, Maiko; Zhao, Yue; Zhu, Li; Yasuda, Sanae
发表日期：2025
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Real-World Comparative Effectiveness of Ferric Derisomaltose Versus Conventional Iron Treatment in Postpartum Hemorrhage-Related Anemia

产后出血相关性贫血中，铁麦芽糖与传统铁剂治疗的真实世界疗效比较

期刊:Cureus Journal of Medical Science
影响因子:1.3
doi:10.7759/cureus.93490
Misugi, Takuya; Nakamoto, Emi; Kurihara, Yasushi; Kitada, Kohei; Hamuro, Akihiro; Tahara, Mie; Nakano, Akemi; Tachibana, Daisuke
贫血
代谢
发表日期：2025
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Guttae Morphology After Cultured Corneal Endothelial Cell Transplant in Fuchs Endothelial Corneal Dystrophy

Fuchs内皮性角膜营养不良患者接受体外培养的角膜内皮细胞移植后，角膜滴状突起的形态

期刊:Jama Ophthalmology
影响因子:9.2
doi:10.1001/jamaophthalmol.2024.2718
Tomioka, Yasufumi; Ueno, Morio; Yamamoto, Akihisa; Numa, Kohsaku; Tanaka, Hiroshi; Kitazawa, Koji; Toda, Munetoyo; Koizumi, Noriko; Tanaka, Motomu; Hamuro, Junji; Sotozono, Chie; Kinoshita, Shigeru
信号转导
细胞生物学
内皮细胞
发表日期：2024
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Clustered ARPE-19 cells distinct in mitochondrial membrane potential may play a pivotal role in cell differentiation

聚集的 ARPE-19 细胞在线粒体膜电位方面具有独特性，可能在细胞分化中发挥关键作用

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-73145-w
Takafumi Miyatani, Hiroshi Tanaka, Kosaku Numa, Asako Uehara, Yohei Otsuki, Junji Hamuro, Shigeru Kinoshita, Chie Sotozono
细胞生物学
其它细胞
发表日期：2024
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