Targeting both tumour-associated CXCR2(+) neutrophils and CCR2(+) macrophages disrupts myeloid recruitment and improves chemotherapeutic responses in pancreatic ductal adenocarcinoma
靶向肿瘤相关CXCR2(+)中性粒细胞和CCR2(+)巨噬细胞可破坏髓系细胞募集，并改善胰腺导管腺癌的化疗反应。
期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2017-313738
Nywening, Timothy M; Belt, Brian A; Cullinan, Darren R; Panni, Roheena Z; Han, Booyeon J; Sanford, Dominic E; Jacobs, Ryan C; Ye, Jian; Patel, Ankit A; Gillanders, William E; Fields, Ryan C; DeNardo, David G; Hawkins, William G; Goedegebuure, Peter; Linehan, David C
CXCR2
粒细胞
免疫/内分泌
巨噬细胞
CR2
中性粒细胞
肿瘤
细胞生物学
肿瘤免疫
巨噬细胞
