HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation
HDAC3 抑制剂 RGFP966 通过下调 P2X7R/STAT3/NF-κB65/NLRP3 活性改善了 Cuprizone 诱导的脱髓鞘小鼠模型和 LPS 刺激的 BV2 细胞中的神经炎症
期刊:ACS Chemical Neuroscience
影响因子:4.1
doi:10.1021/acschemneuro.1c00826
Wei Sun, Ning Zhang, Bingyi Liu, Junrong Yang, Gabriele Loers, Hans-Christian Siebert, Min Wen, Xuexing Zheng, Zhengping Wang, Jun Han, Ruiyan Zhang
信号转导
免疫
神经
神经炎症
其它细胞
NF-κB
Mouse
