Han Xuejie相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

SIRT1 deficiency promotes age-related heart failure through enhancing ferroptosis via GATA4-HADHA-GPX4 axis.

SIRT1 缺陷通过 GATA4-HADHA-GPX4 轴增强铁死亡，从而促进与年龄相关的心力衰竭。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-026-08634-z

Duan Yu, Luo Yingchun, Han Xuejie, Yu Hui, Liu Hanwen, Zhou Yun, Gao Yunlong, Xu Qian, Wei Ying, Min Ruoxin, Hong Yong, Ji Xuanrui, Jia Haibo, Li Yue, Zhang Yun

发表日期：2026

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Gut microbiota dysbiosis promotes chronic kidney disease-associated atrial fibrillation through activation of the NLRP3 inflammasome

肠道菌群失调通过激活NLRP3炎症小体促进慢性肾脏病相关性房颤的发生。

期刊:Europace

影响因子:7.4

doi:10.1093/europace/euag037

Han, Xuejie; Yu, Hui; Gao, Qianhui; Wang, Xiaoyu; Zhang, Linwei; Zhao, Qian; Yu, Luyang; Zhang, Yun; Sui, Manshu; Li, Yue

免疫/内分泌

发表日期：2026

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Yixin Yangshen Granules Target HIF-1 Signaling to Modulate the Neuroimmune Microenvironment in Alzheimer's Disease: Insights from Integrative Multi-Omics and Deep Learning.

益心养生颗粒靶向 HIF-1 信号通路调节阿尔茨海默病神经免疫微环境：来自整合多组学和深度学习的见解。

期刊:Pharmaceuticals

影响因子:4.8

doi:10.3390/ph19030502

Wang Zhihao, Wang Linshuang, Zhang Yusheng, Yang Sixia, Shi Bo, Liu Dasheng, Zhang Han, Xiao Wan, Zhang Junying, Han Xuejie, Wei Dongfeng

发表日期：2026

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Integrative analysis of transcriptome and single-cell sequencing combined with experimental validation identifies biomarkers associated with T cell and senescence in sepsis

转录组和单细胞测序的整合分析结合实验验证，鉴定出与脓毒症中T细胞和衰老相关的生物标志物。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-026-38559-8

Yang, Kairui; Hu, Yunlong; Ma, Chunhui; Wang, Jianing; Wang, Yang; Han, Xuejie; Lv, Jiafeng; Zhang, Xiaolei; Cui, Yunliang

细胞生物学

免疫/内分泌

发表日期：2026

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Faecalibacterium prausnitzii prevents age-related heart failure by suppressing ferroptosis in cardiomyocytes through butyrate-mediated LCN2 regulation.

粪杆菌通过丁酸介导的 LCN2 调节抑制心肌细胞中的铁死亡，从而预防与年龄相关的心力衰竭

期刊:Gut Microbes

影响因子:11

doi:10.1080/19490976.2025.2505119

Zhang Yun, Wei Ying, Han Xuejie, Shi Ling, Yu Hui, Ji Xuanrui, Gao Yunlong, Gao Qianhui, Zhang Linwei, Duan Yu, Li Wenpeng, Yuan Yue, Shi Jing, Cheng Liang, Li Yue

细胞生物学

发表日期：2025

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Atrial Fibroblasts-Derived Extracellular Vesicles Exacerbate Atrial Arrhythmogenesis

心房成纤维细胞来源的细胞外囊泡加剧心房心律失常的发生

期刊:Advanced Science

doi:10.1002/advs.202507627

Yuan, Yue; Zhao, Xinbo; Han, Xuejie; Cao, Yukai; Jin, Xuexin; Shi, Ling; Bi, Xin; Li, Desheng; Zhang, Yun; Ma, Wenbo; Song, Jiahui; Pan, Zhenwei; Zhang, Zhiren; Li, Yue

成纤维细胞

细胞生物学

发表日期：2025

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Circulating exosome long non-coding RNAs are associated with atrial structural remodeling by increasing systemic inflammation in atrial fibrillation patients

循环外泌体长链非编码RNA通过增加房颤患者的全身炎症反应，与心房结构重塑相关。

期刊:Journal of Translational Internal Medicine

影响因子:7.4

doi:10.2478/jtim-2023-0129

Yuan, Yue; Han, Xuejie; Zhao, Xinbo; Zhang, Haiyu; Vinograd, Asiia; Bi, Xin; Duan, Xiaoxu; Cao, Yukai; Gao, Qiang; Song, Jia; Sheng, Li; Li, Yue

发表日期：2024

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Chinese patent medicine combined with calcium channel blockers in the treatment of essential hypertension:a Bayes network meta-analysis and systematic review

中成药联合钙通道阻滞剂治疗原发性高血压：贝叶斯网络荟萃分析和系统评价

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2024.1321405

Cui, Liangyu; Liu, Xingfang; Li, Yukun; Jing, Tianyue; Liu, Dasheng; Ren, Cong; Yin, Tong; Wang, Yu; Zhao, Zhiwei; Wang, Jiaheng; Han, Xuejie; Wang, Liying

发表日期：2024

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Elucidating the anti-hypertensive mechanisms of Uncaria rhynchophylla-Alisma plantago-aquatica L: an integrated network pharmacology, cluster analysis, and molecular docking approach

阐明钩藤-泽泻抗高血压机制：一种整合网络药理学、聚类分析和分子对接的方法

期刊:Frontiers in Chemistry

影响因子:4.2

doi:10.3389/fchem.2024.1356458

Yin, Tong; Zhang, Han; Liu, Xingfang; Wei, Dongfeng; Ren, Cong; Cui, Liangyu; Li, Yukun; Wang, Linshuang; Wang, Jiaheng; Zhao, Zhiwei; Liu, Dasheng; Wang, Liying; Han, Xuejie

发表日期：2024

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Cortical lipid metabolic pathway alteration of early Alzheimer's disease and candidate drugs screen

早期阿尔茨海默病皮质脂质代谢通路改变及候选药物筛选

期刊:European Journal of Medical Research

影响因子:3.4

doi:10.1186/s40001-024-01730-w

Wang, Linshuang; Qu, Fengxue; Yu, Xueyun; Yang, Sixia; Zhao, Binbin; Chen, Yaojing; Li, Pengbo; Zhang, Zhanjun; Zhang, Junying; Han, Xuejie; Wei, Dongfeng

阿尔茨海默症

发表日期：2024

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