日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

High-Throughput In Vivo Screening Using Barcoded mRNA Identifies Lipid Nanoparticles With Extrahepatic Tropism for In Situ Immunoengineering

利用条形码mRNA进行高通量体内筛选，鉴定出具有肝外趋向性的脂质纳米颗粒，用于原位免疫工程

期刊:Advanced Materials
影响因子:26.8
doi:10.1002/adma.202514370
Hamilton, Alex G; Thatte, Ajay S; Xu, Junchao; Luo, Zhangyi; Safford, Hannah C; Swingle, Kelsey L; Muscat-Rivera, Jenna; Kegel, Michael; Han, Xuexiang; Joseph, Ryann A; Murray, Amanda M; Geisler, Hannah C; Whitaker, Ricardo C; Xue, Lulu; Spektor, Roman; Melamed, Jilian R; Weissman, Drew; Mitchell, Michael J
免疫/内分泌
发表日期：2026
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Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

用于递送 CRISPR 基因编辑组分的脂质纳米颗粒

期刊:Small Methods
影响因子:9.1
doi:10.1002/smtd.202401632
Wu, Fan; Li, Nei; Xiao, Yudian; Palanki, Rohan; Yamagata, Hannah; Mitchell, Michael J; Han, Xuexiang
发表日期：2026
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Placenta-tropic VEGF mRNA lipid nanoparticles ameliorate murine pre-eclampsia.

胎盘趋向性 VEGF mRNA 脂质纳米颗粒可改善小鼠先兆子痫

期刊:Nature
影响因子:48.5
doi:10.1038/s41586-024-08291-2
Swingle Kelsey L, Hamilton Alex G, Safford Hannah C, Geisler Hannah C, Thatte Ajay S, Palanki Rohan, Murray Amanda M, Han Emily L, Mukalel Alvin J, Han Xuexiang, Joseph Ryann A, Ghalsasi Aditi A, Alameh Mohamad-Gabriel, Weissman Drew, Mitchell Michael J
其它
发表日期：2025
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Author Correction: Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering

作者更正：分支内体破坏剂（BEND）脂质介导mRNA和CRISPR-Cas9核糖核蛋白复合物的递送，用于肝脏基因编辑和T细胞工程。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-64899-6
Padilla, Marshall S; Mrksich, Kaitlin; Wang, Yiming; Haley, Rebecca M; Li, Jacqueline J; Han, Emily L; El-Mayta, Rakan; Kim, Emily H; Dias, Sofia; Gong, Ningqiang; Teerdhala, Sridatta V; Han, Xuexiang; Chowdhary, Vivek; Xue, Lulu; Siddiqui, Zain; Yamagata, Hannah M; Kim, Dongyoon; Yoon, Il-Chul; Wilson, James M; Radhakrishnan, Ravi; Mitchell, Michael J
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2025
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Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering

分支内体破坏剂（BEND）脂质介导mRNA和CRISPR-Cas9核糖核蛋白复合物的递送，用于肝脏基因编辑和T细胞工程。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-55137-6
Padilla, Marshall S; Mrksich, Kaitlin; Wang, Yiming; Haley, Rebecca M; Li, Jacqueline J; Han, Emily L; El-Mayta, Rakan; Kim, Emily H; Dias, Sofia; Gong, Ningqiang; Teerdhala, Sridatta V; Han, Xuexiang; Chowdhary, Vivek; Xue, Lulu; Siddiqui, Zain; Yamagata, Hannah M; Kim, Dongyoon; Yoon, Il-Chul; Wilson, James M; Radhakrishnan, Ravi; Mitchell, Michael J
细胞生物学
T细胞
T细胞
免疫/内分泌
发表日期：2025
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Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen

利用多臂辅助设计树枝状可降解电离脂质体，促进mRNA向脾脏的系统性递送

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.4c10265
Xue, Lulu; Xiong, Xinhong; Zhao, Gan; Molina-Arocho, William; Palanki, Rohan; Xiao, Zebin; Han, Xuexiang; Yoon, Il-Chul; Figueroa-Espada, Christian G; Xu, Junchao; Gong, Ningqiang; Shi, Qiangqiang; Chen, Qinyuan; Alameh, Mohamad-Gabriel; Vaughan, Andrew E; Haldar, Malay; Wang, Karin; Weissman, Drew; Mitchell, Michael J
发表日期：2025
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Circular RNA lipid nanoparticle vaccine against SARS-CoV-2

针对SARS-CoV-2的环状RNA脂质纳米颗粒疫苗

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2505718122
Swingle, Kelsey L; Hamilton, Alex G; Han, Xuexiang; Liao, Kuo-Chieh; Safford, Hannah C; Thatte, Ajay S; Geisler, Hannah C; Xu, Junchao; Saw, Tzuen Yih; Wan, Yue; Mitchell, Michael J
SARS-CoV-2
发表日期：2025
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Ionizable lipid nanoparticles with functionalized PEG-lipids increase retention in the tumor microenvironment

具有功能化PEG-脂质的可电离脂质纳米颗粒可增加其在肿瘤微环境中的滞留。

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2025.101457
Jester, Matthew; Haley, Rebecca M; Billingsley, Margaret M; Figueroa-Espada, Christian; Joseph, Ryann A; Han, Xuexiang; Mitchell, Michael J
肿瘤
肿瘤微环境
肿瘤免疫
发表日期：2025
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Lipid nanoparticles: Composition, formulation, and application

脂质纳米颗粒：组成、配方和应用

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:4.7
doi:10.1016/j.omtm.2025.101463
Xu, Sijia; Hu, Zhenzhen; Song, Fenglin; Xu, Ying; Han, Xuexiang
发表日期：2025
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Platelet-Mimicking Nanosponges for Functional Reversal of Antiplatelet Agents

用于逆转抗血小板药物功能的血小板模拟纳米海绵

期刊:Circulation Research
影响因子:16.2
doi:10.1161/CIRCRESAHA.122.321034
Xu, Junchao; Yan, Na; Wang, Chunling; Gao, Chao; Han, Xuexiang; Yang, Chengzhi; Xu, Jiaqi; Wang, Kun; Mitchell, Michael J; Zhang, Yinlong; Nie, Guangjun
血小板
发表日期：2023
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